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Literature summary extracted from

  • Baker, F.C.; MAuchamp, B.; Tsai, L.W.; Schooley, D.A.
    Farnesol and farnesal dehydrogenase(s) in corpora allata of the tobacco hornworm moth, Manduca sexta (1983), J. Lipid Res., 24, 1586-1594.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
1.2.1.94 NAD+
-
 Manduca sexta

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.2.1.94 additional information the enzyme is found in all fractions of the cell Manduca sexta
-
-
1.2.1.94 soluble
-
 Manduca sexta
-
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.1.1.354 (2E,6E)-farnesol + NAD+ Manduca sexta
-
 (2E,6E)-farnesal + NADH + H+
-
 ?
1.2.1.94 (2E,6E)-farnesal + NAD+ + H2O Manduca sexta substrate specificity for the 2E-isomer (2E,6E)-farnesoate + NADH + 2 H+
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.354 Manduca sexta
-
-
-
1.2.1.94 Manduca sexta
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.1.1.354 adult
-
 Manduca sexta
-
1.1.1.354 corpora allata
-
 Manduca sexta
-
1.1.1.354 larva
-
 Manduca sexta
-
1.2.1.94 aorta
-
 Manduca sexta
-
1.2.1.94 corpus allatum
-
 Manduca sexta
-
1.2.1.94 additional information not in corpus cardiacum Manduca sexta
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.354 (2E,6E)-farnesol + NAD+
-
 Manduca sexta (2E,6E)-farnesal + NADH + H+
-
 ?
1.2.1.94 (2E,6E)-farnesal + NAD+ + H2O substrate specificity for the 2E-isomer Manduca sexta (2E,6E)-farnesoate + NADH + 2 H+
-
 ?
1.2.1.94 additional information no activity with the (2Z,6E)-farnesal Manduca sexta ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.2.1.94 farnesal dehydrogenase
-
 Manduca sexta

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.354 NAD+ dependent on NAD+, cannot be replaced by NADP+ Manduca sexta
1.2.1.94 additional information no activity with NADP+ Manduca sexta
1.2.1.94 NAD+ dependent on Manduca sexta