Any feedback?
Literature summary extracted from
- Glutamate decarboxylase of the parasitic arthropods Ctenocephalides felis and Rhipicephalus microplus: gene identification, cloning, expression, assay development, identification of inhibitors by high throughput screening and comparison with the orthologs (2013), Insect Biochem. Mol. Biol., 43, 162-177.
Cloned(Commentary)
| EC Number | Cloned (Comment) | Organism |
|---|---|---|
| 4.1.1.15 | gene gad, DNA and amino acid sequence determination and analysis, cloning in Escherichia coli strain DH5alpha, expression of His-tagged enzyme in Escherichia coli strain M15 | Ctenocephalides felis |
| 4.1.1.15 | gene gad, DNA and amino acid sequence determination and analysis, cloning in Escherichia coli strain DH5alpha, expression of His-tagged enzyme in Escherichia coli strain M15 | Rhipicephalus microplus |
| 4.1.1.15 | gene gad, expression of enzyme as maltose-bindig protein fusion protein in Escherichia coli strain TB1 | Drosophila melanogaster |
| 4.1.1.15 | gene gad65, expression of the enzyme as maltose-bindig protein fusion protein in Escherichia coli strain TB1 | Mus musculus |
| 4.1.1.15 | gene gad67, expression of the isozyme as maltose-bindig protein fusion protein in Escherichia coli strain TB1 | Mus musculus |
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 4.1.1.15 | (4Z,7E)-N,N'-dihydroxy-2,2-dimethyl-5,6-dihydro-2H-benzimidazole-4,7-diimine | - |
Ctenocephalides felis |  |
| 4.1.1.15 | (4Z,7E)-N,N'-dihydroxy-2,2-dimethyl-5,6-dihydro-2H-benzimidazole-4,7-diimine | - |
Drosophila melanogaster | |
| 4.1.1.15 | (4Z,7E)-N,N'-dihydroxy-2,2-dimethyl-5,6-dihydro-2H-benzimidazole-4,7-diimine | - |
Mus musculus | |
| 4.1.1.15 | (4Z,7E)-N,N'-dihydroxy-2,2-dimethyl-5,6-dihydro-2H-benzimidazole-4,7-diimine | - |
Rhipicephalus microplus | |
| 4.1.1.15 | (5Z)-2-amino-5-(2-nitrobenzylidene)-1,3-thiazol-4(5H)-one | - |
Ctenocephalides felis | |
| 4.1.1.15 | (5Z)-2-amino-5-(2-nitrobenzylidene)-1,3-thiazol-4(5H)-one | - |
Drosophila melanogaster | |
| 4.1.1.15 | (5Z)-2-amino-5-(2-nitrobenzylidene)-1,3-thiazol-4(5H)-one | - |
Mus musculus | |
| 4.1.1.15 | (5Z)-2-amino-5-(2-nitrobenzylidene)-1,3-thiazol-4(5H)-one | - |
Rhipicephalus microplus | |
| 4.1.1.15 | 1,4-dioxo-1,2,3,4-tetrahydronaphthalen-2-yl 2,3,4-tri-O-acetylpentopyranoside | - |
Ctenocephalides felis | |
| 4.1.1.15 | 1,4-dioxo-1,2,3,4-tetrahydronaphthalen-2-yl 2,3,4-tri-O-acetylpentopyranoside | - |
Drosophila melanogaster | |
| 4.1.1.15 | 1,4-dioxo-1,2,3,4-tetrahydronaphthalen-2-yl 2,3,4-tri-O-acetylpentopyranoside | - |
Mus musculus | |
| 4.1.1.15 | 1,4-dioxo-1,2,3,4-tetrahydronaphthalen-2-yl 2,3,4-tri-O-acetylpentopyranoside | - |
Rhipicephalus microplus | |
| 4.1.1.15 | 1-(2-nitrobenzyl)-1H-indole-3-carbaldehyde | - |
Ctenocephalides felis | |
| 4.1.1.15 | 1-(2-nitrobenzyl)-1H-indole-3-carbaldehyde | - |
Drosophila melanogaster | |
| 4.1.1.15 | 1-(2-nitrobenzyl)-1H-indole-3-carbaldehyde | - |
Mus musculus | |
| 4.1.1.15 | 1-(2-nitrobenzyl)-1H-indole-3-carbaldehyde | - |
Rhipicephalus microplus | |
| 4.1.1.15 | 10H-indeno[2,1-e]tetrazolo[1,5-b][1,2,4]triazin-10-one | - |
Ctenocephalides felis | |
| 4.1.1.15 | 10H-indeno[2,1-e]tetrazolo[1,5-b][1,2,4]triazin-10-one | - |
Drosophila melanogaster | |
| 4.1.1.15 | 10H-indeno[2,1-e]tetrazolo[1,5-b][1,2,4]triazin-10-one | - |
Mus musculus | |
| 4.1.1.15 | 10H-indeno[2,1-e]tetrazolo[1,5-b][1,2,4]triazin-10-one | - |
Rhipicephalus microplus | |
| 4.1.1.15 | 2,4-bis[2-(4-hydroxyphenyl)propan-2-yl]phenol | - |
Ctenocephalides felis | |
| 4.1.1.15 | 2,4-bis[2-(4-hydroxyphenyl)propan-2-yl]phenol | - |
Drosophila melanogaster | |
| 4.1.1.15 | 2,4-bis[2-(4-hydroxyphenyl)propan-2-yl]phenol | - |
Mus musculus | |
| 4.1.1.15 | 2,4-bis[2-(4-hydroxyphenyl)propan-2-yl]phenol | - |
Rhipicephalus microplus | |
| 4.1.1.15 | 2-(benzylsulfanyl)-3-(morpholin-4-yl)-2,3-dihydronaphthalene-1,4-dione | - |
Ctenocephalides felis | |
| 4.1.1.15 | 2-(benzylsulfanyl)-3-(morpholin-4-yl)-2,3-dihydronaphthalene-1,4-dione | - |
Drosophila melanogaster | |
| 4.1.1.15 | 2-(benzylsulfanyl)-3-(morpholin-4-yl)-2,3-dihydronaphthalene-1,4-dione | - |
Mus musculus | |
| 4.1.1.15 | 2-(benzylsulfanyl)-3-(morpholin-4-yl)-2,3-dihydronaphthalene-1,4-dione | - |
Rhipicephalus microplus | |
| 4.1.1.15 | 2-chloro-N-[5-([2-oxo-2-[(4-sulfamoylphenyl)amino]ethyl]sulfanyl)-1,3,4-thiadiazol-2-yl]acetamide | - |
Ctenocephalides felis | |
| 4.1.1.15 | 2-chloro-N-[5-([2-oxo-2-[(4-sulfamoylphenyl)amino]ethyl]sulfanyl)-1,3,4-thiadiazol-2-yl]acetamide | - |
Drosophila melanogaster | |
| 4.1.1.15 | 2-chloro-N-[5-([2-oxo-2-[(4-sulfamoylphenyl)amino]ethyl]sulfanyl)-1,3,4-thiadiazol-2-yl]acetamide | - |
Mus musculus | |
| 4.1.1.15 | 2-chloro-N-[5-([2-oxo-2-[(4-sulfamoylphenyl)amino]ethyl]sulfanyl)-1,3,4-thiadiazol-2-yl]acetamide | - |
Rhipicephalus microplus | |
| 4.1.1.15 | 2-hydroxy-2-(2-hydroxy-6-oxocyclohex-2-en-1-yl)-1H-indene-1,3(2H)-dione | - |
Ctenocephalides felis | |
| 4.1.1.15 | 2-hydroxy-2-(2-hydroxy-6-oxocyclohex-2-en-1-yl)-1H-indene-1,3(2H)-dione | - |
Drosophila melanogaster | |
| 4.1.1.15 | 2-hydroxy-2-(2-hydroxy-6-oxocyclohex-2-en-1-yl)-1H-indene-1,3(2H)-dione | - |
Mus musculus | |
| 4.1.1.15 | 2-hydroxy-2-(2-hydroxy-6-oxocyclohex-2-en-1-yl)-1H-indene-1,3(2H)-dione | - |
Rhipicephalus microplus | |
| 4.1.1.15 | 2-thioxo-3-[(E)-(3,3,5-trimethylcyclohexylidene)amino]-1,3-thiazolidin-4-one | - |
Ctenocephalides felis | |
| 4.1.1.15 | 2-thioxo-3-[(E)-(3,3,5-trimethylcyclohexylidene)amino]-1,3-thiazolidin-4-one | - |
Drosophila melanogaster | |
| 4.1.1.15 | 2-thioxo-3-[(E)-(3,3,5-trimethylcyclohexylidene)amino]-1,3-thiazolidin-4-one | - |
Mus musculus | |
| 4.1.1.15 | 2-thioxo-3-[(E)-(3,3,5-trimethylcyclohexylidene)amino]-1,3-thiazolidin-4-one | - |
Rhipicephalus microplus | |
| 4.1.1.15 | 2-[(2-chloro-5-nitrobenzoyl)amino]-5-iodobenzoic acid | - |
Ctenocephalides felis | |
| 4.1.1.15 | 2-[(2-chloro-5-nitrobenzoyl)amino]-5-iodobenzoic acid | - |
Drosophila melanogaster | |
| 4.1.1.15 | 2-[(2-chloro-5-nitrobenzoyl)amino]-5-iodobenzoic acid | - |
Mus musculus | |
| 4.1.1.15 | 2-[(2-chloro-5-nitrobenzoyl)amino]-5-iodobenzoic acid | - |
Rhipicephalus microplus | |
| 4.1.1.15 | 2-[(3-formyl-1H-indol-1-yl)methyl]benzonitrile | - |
Ctenocephalides felis | |
| 4.1.1.15 | 2-[(3-formyl-1H-indol-1-yl)methyl]benzonitrile | - |
Drosophila melanogaster | |
| 4.1.1.15 | 2-[(3-formyl-1H-indol-1-yl)methyl]benzonitrile | - |
Mus musculus | |
| 4.1.1.15 | 2-[(3-formyl-1H-indol-1-yl)methyl]benzonitrile | - |
Rhipicephalus microplus | |
| 4.1.1.15 | 3,3'-(4H-1,2,4-triazole-3,5-diyl)bis(4-nitro-1,2,5-oxadiazole) | - |
Ctenocephalides felis | |
| 4.1.1.15 | 3,3'-(4H-1,2,4-triazole-3,5-diyl)bis(4-nitro-1,2,5-oxadiazole) | - |
Drosophila melanogaster | |
| 4.1.1.15 | 3,3'-(4H-1,2,4-triazole-3,5-diyl)bis(4-nitro-1,2,5-oxadiazole) | - |
Mus musculus | |
| 4.1.1.15 | 3,3'-(4H-1,2,4-triazole-3,5-diyl)bis(4-nitro-1,2,5-oxadiazole) | - |
Rhipicephalus microplus | |
| 4.1.1.15 | 3-[(2E)-2-[1-(3,4-dimethoxyphenyl)ethylidene]hydrazinyl]benzoic acid | - |
Ctenocephalides felis | |
| 4.1.1.15 | 3-[(2E)-2-[1-(3,4-dimethoxyphenyl)ethylidene]hydrazinyl]benzoic acid | - |
Drosophila melanogaster | |
| 4.1.1.15 | 3-[(2E)-2-[1-(3,4-dimethoxyphenyl)ethylidene]hydrazinyl]benzoic acid | - |
Mus musculus | |
| 4.1.1.15 | 3-[(2E)-2-[1-(3,4-dimethoxyphenyl)ethylidene]hydrazinyl]benzoic acid | - |
Rhipicephalus microplus | |
| 4.1.1.15 | 3-[(E)-(2,6-difluorobenzylidene)amino]-2-thioxo-1,3-thiazolidin-4-one | - |
Ctenocephalides felis | |
| 4.1.1.15 | 3-[(E)-(2,6-difluorobenzylidene)amino]-2-thioxo-1,3-thiazolidin-4-one | - |
Drosophila melanogaster | |
| 4.1.1.15 | 3-[(E)-(2,6-difluorobenzylidene)amino]-2-thioxo-1,3-thiazolidin-4-one | - |
Mus musculus | |
| 4.1.1.15 | 3-[(E)-(2,6-difluorobenzylidene)amino]-2-thioxo-1,3-thiazolidin-4-one | - |
Rhipicephalus microplus | |
| 4.1.1.15 | 3-[(E)-(4-methoxybenzylidene)amino]-2-thioxo-1,3-thiazolidin-4-one | - |
Ctenocephalides felis | |
| 4.1.1.15 | 3-[(E)-(4-methoxybenzylidene)amino]-2-thioxo-1,3-thiazolidin-4-one | - |
Drosophila melanogaster | |
| 4.1.1.15 | 3-[(E)-(4-methoxybenzylidene)amino]-2-thioxo-1,3-thiazolidin-4-one | - |
Mus musculus | |
| 4.1.1.15 | 3-[(E)-(4-methoxybenzylidene)amino]-2-thioxo-1,3-thiazolidin-4-one | - |
Rhipicephalus microplus | |
| 4.1.1.15 | 4,4'-(phenylmethanediyl)bis[2-(4-chlorophenyl)-5-methyl-2,4-dihydro-3H-pyrazol-3-one] | - |
Ctenocephalides felis | |
| 4.1.1.15 | 4,4'-(phenylmethanediyl)bis[2-(4-chlorophenyl)-5-methyl-2,4-dihydro-3H-pyrazol-3-one] | - |
Drosophila melanogaster | |
| 4.1.1.15 | 4,4'-(phenylmethanediyl)bis[2-(4-chlorophenyl)-5-methyl-2,4-dihydro-3H-pyrazol-3-one] | - |
Mus musculus | |
| 4.1.1.15 | 4,4'-(phenylmethanediyl)bis[2-(4-chlorophenyl)-5-methyl-2,4-dihydro-3H-pyrazol-3-one] | - |
Rhipicephalus microplus | |
| 4.1.1.15 | 4,4'-[(4-hydroxyphenyl)methanediyl]bis(2-heptyl-5-methyl-2,4-dihydro-3H-pyrazol-3-one) | - |
Ctenocephalides felis | |
| 4.1.1.15 | 4,4'-[(4-hydroxyphenyl)methanediyl]bis(2-heptyl-5-methyl-2,4-dihydro-3H-pyrazol-3-one) | - |
Drosophila melanogaster | |
| 4.1.1.15 | 4,4'-[(4-hydroxyphenyl)methanediyl]bis(2-heptyl-5-methyl-2,4-dihydro-3H-pyrazol-3-one) | - |
Mus musculus | |
| 4.1.1.15 | 4,4'-[(4-hydroxyphenyl)methanediyl]bis(2-heptyl-5-methyl-2,4-dihydro-3H-pyrazol-3-one) | - |
Rhipicephalus microplus | |
| 4.1.1.15 | 4-(morpholin-4-yl)naphthalene-1,2-dione | - |
Ctenocephalides felis | |
| 4.1.1.15 | 4-(morpholin-4-yl)naphthalene-1,2-dione | - |
Drosophila melanogaster | |
| 4.1.1.15 | 4-(morpholin-4-yl)naphthalene-1,2-dione | - |
Mus musculus | |
| 4.1.1.15 | 4-(morpholin-4-yl)naphthalene-1,2-dione | - |
Rhipicephalus microplus | |
| 4.1.1.15 | 4-(piperidin-1-yl)naphthalene-1,2-dione | - |
Ctenocephalides felis | |
| 4.1.1.15 | 4-(piperidin-1-yl)naphthalene-1,2-dione | - |
Drosophila melanogaster | |
| 4.1.1.15 | 4-(piperidin-1-yl)naphthalene-1,2-dione | - |
Mus musculus | |
| 4.1.1.15 | 4-(piperidin-1-yl)naphthalene-1,2-dione | - |
Rhipicephalus microplus | |
| 4.1.1.15 | 4-nitro-1,6-dihydrobenzo[1,2-d:3,4-d']bis[1,2,3]triazole | - |
Ctenocephalides felis | |
| 4.1.1.15 | 4-nitro-1,6-dihydrobenzo[1,2-d:3,4-d']bis[1,2,3]triazole | - |
Drosophila melanogaster | |
| 4.1.1.15 | 4-nitro-1,6-dihydrobenzo[1,2-d:3,4-d']bis[1,2,3]triazole | - |
Mus musculus | |
| 4.1.1.15 | 4-nitro-1,6-dihydrobenzo[1,2-d:3,4-d']bis[1,2,3]triazole | - |
Rhipicephalus microplus | |
| 4.1.1.15 | 4-nitro-7-[[(1-phenyl-1H-tetrazol-5-yl)sulfanyl]methyl]-2,1,3-benzothiadiazole | - |
Ctenocephalides felis | |
| 4.1.1.15 | 4-nitro-7-[[(1-phenyl-1H-tetrazol-5-yl)sulfanyl]methyl]-2,1,3-benzothiadiazole | - |
Drosophila melanogaster | |
| 4.1.1.15 | 4-nitro-7-[[(1-phenyl-1H-tetrazol-5-yl)sulfanyl]methyl]-2,1,3-benzothiadiazole | - |
Mus musculus | |
| 4.1.1.15 | 4-nitro-7-[[(1-phenyl-1H-tetrazol-5-yl)sulfanyl]methyl]-2,1,3-benzothiadiazole | - |
Rhipicephalus microplus | |
| 4.1.1.15 | 4-[(1,4-dioxo-1,2,3,4-tetrahydronaphthalen-2-yl)sulfanyl]butanoic acid | - |
Ctenocephalides felis | |
| 4.1.1.15 | 4-[(1,4-dioxo-1,2,3,4-tetrahydronaphthalen-2-yl)sulfanyl]butanoic acid | - |
Drosophila melanogaster | |
| 4.1.1.15 | 4-[(1,4-dioxo-1,2,3,4-tetrahydronaphthalen-2-yl)sulfanyl]butanoic acid | - |
Mus musculus | |
| 4.1.1.15 | 4-[(1,4-dioxo-1,2,3,4-tetrahydronaphthalen-2-yl)sulfanyl]butanoic acid | - |
Rhipicephalus microplus | |
| 4.1.1.15 | 5,6-dichloro-2,1,3-benzothiadiazole-4,7-diol | - |
Ctenocephalides felis | |
| 4.1.1.15 | 5,6-dichloro-2,1,3-benzothiadiazole-4,7-diol | - |
Drosophila melanogaster | |
| 4.1.1.15 | 5,6-dichloro-2,1,3-benzothiadiazole-4,7-diol | - |
Mus musculus | |
| 4.1.1.15 | 5,6-dichloro-2,1,3-benzothiadiazole-4,7-diol | - |
Rhipicephalus microplus | |
| 4.1.1.15 | 5-[(E)-benzylideneamino]-6-[(2-hydroxyethyl)amino]pyrimidine-2,4(1H,3H)-dione | - |
Ctenocephalides felis | |
| 4.1.1.15 | 5-[(E)-benzylideneamino]-6-[(2-hydroxyethyl)amino]pyrimidine-2,4(1H,3H)-dione | - |
Drosophila melanogaster | |
| 4.1.1.15 | 5-[(E)-benzylideneamino]-6-[(2-hydroxyethyl)amino]pyrimidine-2,4(1H,3H)-dione | - |
Mus musculus | |
| 4.1.1.15 | 5-[(E)-benzylideneamino]-6-[(2-hydroxyethyl)amino]pyrimidine-2,4(1H,3H)-dione | - |
Rhipicephalus microplus | |
| 4.1.1.15 | 5-[(E)-[[1-(2-chlorobenzyl)-1H-indol-3-yl]methylidene]amino]-1,3-dihydro-2H-benzimidazol-2-one | - |
Ctenocephalides felis | |
| 4.1.1.15 | 5-[(E)-[[1-(2-chlorobenzyl)-1H-indol-3-yl]methylidene]amino]-1,3-dihydro-2H-benzimidazol-2-one | - |
Drosophila melanogaster | |
| 4.1.1.15 | 5-[(E)-[[1-(2-chlorobenzyl)-1H-indol-3-yl]methylidene]amino]-1,3-dihydro-2H-benzimidazol-2-one | - |
Mus musculus | |
| 4.1.1.15 | 5-[(E)-[[1-(2-chlorobenzyl)-1H-indol-3-yl]methylidene]amino]-1,3-dihydro-2H-benzimidazol-2-one | - |
Rhipicephalus microplus | |
| 4.1.1.15 | 5-[[5-hydroxy-3-methyl-1-(4-methylphenyl)-1H-pyrazol-4-yl]methylidene]-1,3-diphenyl-2-thioxodihydropyrimidine-4,6(1H,5H)-dione | - |
Ctenocephalides felis | |
| 4.1.1.15 | 5-[[5-hydroxy-3-methyl-1-(4-methylphenyl)-1H-pyrazol-4-yl]methylidene]-1,3-diphenyl-2-thioxodihydropyrimidine-4,6(1H,5H)-dione | - |
Drosophila melanogaster | |
| 4.1.1.15 | 5-[[5-hydroxy-3-methyl-1-(4-methylphenyl)-1H-pyrazol-4-yl]methylidene]-1,3-diphenyl-2-thioxodihydropyrimidine-4,6(1H,5H)-dione | - |
Mus musculus | |
| 4.1.1.15 | 5-[[5-hydroxy-3-methyl-1-(4-methylphenyl)-1H-pyrazol-4-yl]methylidene]-1,3-diphenyl-2-thioxodihydropyrimidine-4,6(1H,5H)-dione | - |
Rhipicephalus microplus | |
| 4.1.1.15 | 6,11-dioxo-5a,6,11,11a-tetrahydronaphtho[2',3':4,5][1,3]thiazolo[3,2-a]pyridin-12-ium | - |
Ctenocephalides felis | |
| 4.1.1.15 | 6,11-dioxo-5a,6,11,11a-tetrahydronaphtho[2',3':4,5][1,3]thiazolo[3,2-a]pyridin-12-ium | - |
Drosophila melanogaster | |
| 4.1.1.15 | 6,11-dioxo-5a,6,11,11a-tetrahydronaphtho[2',3':4,5][1,3]thiazolo[3,2-a]pyridin-12-ium | - |
Mus musculus | |
| 4.1.1.15 | 6,11-dioxo-5a,6,11,11a-tetrahydronaphtho[2',3':4,5][1,3]thiazolo[3,2-a]pyridin-12-ium | - |
Rhipicephalus microplus | |
| 4.1.1.15 | 9H-indeno[1,2-b][1,2,5]oxadiazolo[3,4-e]pyrazin-9-one | - |
Ctenocephalides felis | |
| 4.1.1.15 | 9H-indeno[1,2-b][1,2,5]oxadiazolo[3,4-e]pyrazin-9-one | - |
Drosophila melanogaster | |
| 4.1.1.15 | 9H-indeno[1,2-b][1,2,5]oxadiazolo[3,4-e]pyrazin-9-one | - |
Mus musculus | |
| 4.1.1.15 | 9H-indeno[1,2-b][1,2,5]oxadiazolo[3,4-e]pyrazin-9-one | - |
Rhipicephalus microplus | |
| 4.1.1.15 | biphenyl-3,3'-dicarbaldehyde | - |
Ctenocephalides felis | |
| 4.1.1.15 | biphenyl-3,3'-dicarbaldehyde | - |
Drosophila melanogaster | |
| 4.1.1.15 | biphenyl-3,3'-dicarbaldehyde | - |
Mus musculus | |
| 4.1.1.15 | biphenyl-3,3'-dicarbaldehyde | - |
Rhipicephalus microplus | |
| 4.1.1.15 | carboxymethoxylamine | - |
Ctenocephalides felis | |
| 4.1.1.15 | carboxymethoxylamine | - |
Drosophila melanogaster | |
| 4.1.1.15 | carboxymethoxylamine | - |
Mus musculus | |
| 4.1.1.15 | carboxymethoxylamine | - |
Rhipicephalus microplus | |
| 4.1.1.15 | methyl 2-amino-3-oxo-3H-phenothiazine-1-carboxylate | - |
Ctenocephalides felis | |
| 4.1.1.15 | methyl 2-amino-3-oxo-3H-phenothiazine-1-carboxylate | - |
Drosophila melanogaster | |
| 4.1.1.15 | methyl 2-amino-3-oxo-3H-phenothiazine-1-carboxylate | - |
Mus musculus | |
| 4.1.1.15 | methyl 2-amino-3-oxo-3H-phenothiazine-1-carboxylate | - |
Rhipicephalus microplus | |
| 4.1.1.15 | methyl 2-[[(2-methylimidazo[1,2-a]pyridin-3-yl)carbonyl]amino]benzoate | - |
Ctenocephalides felis | |
| 4.1.1.15 | methyl 2-[[(2-methylimidazo[1,2-a]pyridin-3-yl)carbonyl]amino]benzoate | - |
Drosophila melanogaster | |
| 4.1.1.15 | methyl 2-[[(2-methylimidazo[1,2-a]pyridin-3-yl)carbonyl]amino]benzoate | - |
Mus musculus | |
| 4.1.1.15 | methyl 2-[[(2-methylimidazo[1,2-a]pyridin-3-yl)carbonyl]amino]benzoate | - |
Rhipicephalus microplus | |
| 4.1.1.15 | additional information | inhibitor screening, overview | Ctenocephalides felis | |
| 4.1.1.15 | additional information | inhibitor screening, overview | Drosophila melanogaster | |
| 4.1.1.15 | additional information | inhibitor screening, overview; inhibitor screening, overview | Mus musculus | |
| 4.1.1.15 | additional information | inhibitor screening, overview | Rhipicephalus microplus | |
| 4.1.1.15 | N-(2-hydroxy-1,3-dioxo-2,3-dihydro-1H-inden-2-yl)benzamide | - |
Ctenocephalides felis | |
| 4.1.1.15 | N-(2-hydroxy-1,3-dioxo-2,3-dihydro-1H-inden-2-yl)benzamide | - |
Drosophila melanogaster | |
| 4.1.1.15 | N-(2-hydroxy-1,3-dioxo-2,3-dihydro-1H-inden-2-yl)benzamide | - |
Mus musculus | |
| 4.1.1.15 | N-(2-hydroxy-1,3-dioxo-2,3-dihydro-1H-inden-2-yl)benzamide | - |
Rhipicephalus microplus | |
| 4.1.1.15 | N-[4,7-dioxo-6-(phenylamino)-4,7-dihydro-2,1,3-benzoxadiazol-5-yl]acetamide | - |
Ctenocephalides felis | |
| 4.1.1.15 | N-[4,7-dioxo-6-(phenylamino)-4,7-dihydro-2,1,3-benzoxadiazol-5-yl]acetamide | - |
Drosophila melanogaster | |
| 4.1.1.15 | N-[4,7-dioxo-6-(phenylamino)-4,7-dihydro-2,1,3-benzoxadiazol-5-yl]acetamide | - |
Mus musculus | |
| 4.1.1.15 | N-[4,7-dioxo-6-(phenylamino)-4,7-dihydro-2,1,3-benzoxadiazol-5-yl]acetamide | - |
Rhipicephalus microplus | |
| 4.1.1.15 | N-[4,7-dioxo-6-(piperidin-1-yl)-4,7-dihydro-2,1,3-benzoxadiazol-5-yl]acetamide | - |
Ctenocephalides felis | |
| 4.1.1.15 | N-[4,7-dioxo-6-(piperidin-1-yl)-4,7-dihydro-2,1,3-benzoxadiazol-5-yl]acetamide | - |
Drosophila melanogaster | |
| 4.1.1.15 | N-[4,7-dioxo-6-(piperidin-1-yl)-4,7-dihydro-2,1,3-benzoxadiazol-5-yl]acetamide | - |
Mus musculus | |
| 4.1.1.15 | N-[4,7-dioxo-6-(piperidin-1-yl)-4,7-dihydro-2,1,3-benzoxadiazol-5-yl]acetamide | - |
Rhipicephalus microplus | |
| 4.1.1.15 | naphtho[2',3':4,5]imidazo[1,2-a]pyridine-6,11-dione | - |
Ctenocephalides felis | |
| 4.1.1.15 | naphtho[2',3':4,5]imidazo[1,2-a]pyridine-6,11-dione | - |
Drosophila melanogaster | |
| 4.1.1.15 | naphtho[2',3':4,5]imidazo[1,2-a]pyridine-6,11-dione | - |
Mus musculus | |
| 4.1.1.15 | naphtho[2',3':4,5]imidazo[1,2-a]pyridine-6,11-dione | - |
Rhipicephalus microplus | |
| 4.1.1.15 | [(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)oxy]acetic acid | - |
Ctenocephalides felis | |
| 4.1.1.15 | [(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)oxy]acetic acid | - |
Drosophila melanogaster | |
| 4.1.1.15 | [(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)oxy]acetic acid | - |
Mus musculus | |
| 4.1.1.15 | [(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)oxy]acetic acid | - |
Rhipicephalus microplus | |
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 4.1.1.15 | additional information | - |
additional information | Michaelis-Menten kinetics | Mus musculus | |
| 4.1.1.15 | additional information | - |
additional information | Michaelis-Menten kinetics | Ctenocephalides felis | |
| 4.1.1.15 | additional information | - |
additional information | Michaelis-Menten kinetics | Rhipicephalus microplus | |
| 4.1.1.15 | additional information | - |
additional information | Michaelis-Menten kinetics | Drosophila melanogaster | |
| 4.1.1.15 | 5.4 | - |
L-glutamate | pH 8.0, 37°C, recombinant enzyme | Mus musculus | |
| 4.1.1.15 | 6.1 | - |
L-glutamate | pH 8.0, 37°C, recombinant enzyme | Mus musculus | |
| 4.1.1.15 | 8.8 | - |
L-glutamate | pH 8.0, 37°C, recombinant enzyme | Ctenocephalides felis | |
| 4.1.1.15 | 10.1 | - |
L-glutamate | pH 8.0, 37°C, recombinant enzyme | Drosophila melanogaster | |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 4.1.1.15 | L-glutamate | Mus musculus | - |
4-aminobutanoate + CO2 | - |
? | |
| 4.1.1.15 | L-glutamate | Ctenocephalides felis | - |
4-aminobutanoate + CO2 | - |
? | |
| 4.1.1.15 | L-glutamate | Rhipicephalus microplus | - |
4-aminobutanoate + CO2 | - |
? | |
| 4.1.1.15 | L-glutamate | Drosophila melanogaster | - |
4-aminobutanoate + CO2 | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 4.1.1.15 | Ctenocephalides felis | K7WYY0 | gene gad | - |
| 4.1.1.15 | Drosophila melanogaster | P20228 | gene gad | - |
| 4.1.1.15 | Mus musculus | P48318 | isozyme Gad67; gene gad67 encoding isozyme Gad67 | - |
| 4.1.1.15 | Mus musculus | P48320 | isozyme Gad65; gene gad65 encoding isozyme Gad65 | - |
| 4.1.1.15 | Rhipicephalus microplus | K7XPX5 | gene gad | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 4.1.1.15 | L-glutamate | - |
Mus musculus | 4-aminobutanoate + CO2 | - |
? | |
| 4.1.1.15 | L-glutamate | - |
Ctenocephalides felis | 4-aminobutanoate + CO2 | - |
? | |
| 4.1.1.15 | L-glutamate | - |
Rhipicephalus microplus | 4-aminobutanoate + CO2 | - |
? | |
| 4.1.1.15 | L-glutamate | - |
Drosophila melanogaster | 4-aminobutanoate + CO2 | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 4.1.1.15 | GAD | - |
Ctenocephalides felis |
| 4.1.1.15 | GAD | - |
Rhipicephalus microplus |
| 4.1.1.15 | GAD1 | - |
Drosophila melanogaster |
| 4.1.1.15 | Gad56 | - |
Mus musculus |
| 4.1.1.15 | GAD67 | - |
Mus musculus |
| 4.1.1.15 | L-glutamate 1-carboxylyase | - |
Mus musculus |
| 4.1.1.15 | L-glutamate 1-carboxylyase | - |
Ctenocephalides felis |
| 4.1.1.15 | L-glutamate 1-carboxylyase | - |
Rhipicephalus microplus |
| 4.1.1.15 | L-glutamate 1-carboxylyase | - |
Drosophila melanogaster |
Temperature Optimum [°C]
| EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|---|
| 4.1.1.15 | 37 | - |
assay at | Mus musculus |
| 4.1.1.15 | 37 | - |
assay at | Ctenocephalides felis |
| 4.1.1.15 | 37 | - |
assay at | Rhipicephalus microplus |
| 4.1.1.15 | 37 | - |
assay at | Drosophila melanogaster |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 4.1.1.15 | 8 | 8.5 | assay at | Mus musculus |
| 4.1.1.15 | 8 | 8.5 | assay at | Ctenocephalides felis |
| 4.1.1.15 | 8 | 8.5 | assay at | Rhipicephalus microplus |
| 4.1.1.15 | 8 | 8.5 | assay at | Drosophila melanogaster |
IC50 Value
| EC Number | IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
|---|---|---|---|---|---|---|
| 4.1.1.15 | 0.0002 | - |
pH 8.0, 37°C, recombinant enzyme | Mus musculus | 3,3'-(4H-1,2,4-triazole-3,5-diyl)bis(4-nitro-1,2,5-oxadiazole) | |
| 4.1.1.15 | 0.0004 | - |
pH 8.0, 37°C, recombinant enzyme | Drosophila melanogaster | carboxymethoxylamine | |
| 4.1.1.15 | 0.0004 | - |
pH 8.0, 37°C, recombinant enzyme | Mus musculus | 3,3'-(4H-1,2,4-triazole-3,5-diyl)bis(4-nitro-1,2,5-oxadiazole) | |
| 4.1.1.15 | 0.0005 | - |
pH 8.0, 37°C, recombinant enzyme | Mus musculus | carboxymethoxylamine | |
| 4.1.1.15 | 0.001 | - |
pH 8.0, 37°C, recombinant enzyme | Mus musculus | carboxymethoxylamine | |
| 4.1.1.15 | 0.001 | - |
pH 8.0, 37°C, recombinant enzyme | Ctenocephalides felis | carboxymethoxylamine | |
| 4.1.1.15 | 0.001 | - |
pH 8.0, 37°C, recombinant enzyme | Mus musculus | methyl 2-amino-3-oxo-3H-phenothiazine-1-carboxylate | |
| 4.1.1.15 | 0.001 | - |
pH 8.0, 37°C, recombinant enzyme | Drosophila melanogaster | N-[4,7-dioxo-6-(phenylamino)-4,7-dihydro-2,1,3-benzoxadiazol-5-yl]acetamide | |
| 4.1.1.15 | 0.0011 | - |
pH 8.0, 37°C, recombinant enzyme | Ctenocephalides felis | N-[4,7-dioxo-6-(phenylamino)-4,7-dihydro-2,1,3-benzoxadiazol-5-yl]acetamide | |
| 4.1.1.15 | 0.0011 | - |
pH 8.0, 37°C, recombinant enzyme | Rhipicephalus microplus | N-[4,7-dioxo-6-(phenylamino)-4,7-dihydro-2,1,3-benzoxadiazol-5-yl]acetamide | |
| 4.1.1.15 | 0.0012 | - |
pH 8.0, 37°C, recombinant enzyme | Mus musculus | N-[4,7-dioxo-6-(phenylamino)-4,7-dihydro-2,1,3-benzoxadiazol-5-yl]acetamide | |
| 4.1.1.15 | 0.0013 | - |
pH 8.0, 37°C, recombinant enzyme | Drosophila melanogaster | N-[4,7-dioxo-6-(piperidin-1-yl)-4,7-dihydro-2,1,3-benzoxadiazol-5-yl]acetamide | |
| 4.1.1.15 | 0.0014 | - |
pH 8.0, 37°C, recombinant enzyme | Drosophila melanogaster | methyl 2-amino-3-oxo-3H-phenothiazine-1-carboxylate | |
| 4.1.1.15 | 0.0015 | - |
pH 8.0, 37°C, recombinant enzyme | Ctenocephalides felis | methyl 2-amino-3-oxo-3H-phenothiazine-1-carboxylate | |
| 4.1.1.15 | 0.0017 | - |
pH 8.0, 37°C, recombinant enzyme | Rhipicephalus microplus | methyl 2-amino-3-oxo-3H-phenothiazine-1-carboxylate | |
| 4.1.1.15 | 0.0018 | - |
pH 8.0, 37°C, recombinant enzyme | Ctenocephalides felis | N-[4,7-dioxo-6-(piperidin-1-yl)-4,7-dihydro-2,1,3-benzoxadiazol-5-yl]acetamide | |
| 4.1.1.15 | 0.002 | - |
pH 8.0, 37°C, recombinant enzyme | Rhipicephalus microplus | 10H-indeno[2,1-e]tetrazolo[1,5-b][1,2,4]triazin-10-one | |
| 4.1.1.15 | 0.002 | - |
pH 8.0, 37°C, recombinant enzyme | Drosophila melanogaster | 10H-indeno[2,1-e]tetrazolo[1,5-b][1,2,4]triazin-10-one | |
| 4.1.1.15 | 0.002 | - |
pH 8.0, 37°C, recombinant enzyme | Mus musculus | 10H-indeno[2,1-e]tetrazolo[1,5-b][1,2,4]triazin-10-one | |
| 4.1.1.15 | 0.002 | 4 | pH 8.0, 37°C, recombinant enzyme | Ctenocephalides felis | 10H-indeno[2,1-e]tetrazolo[1,5-b][1,2,4]triazin-10-one | |
| 4.1.1.15 | 0.002 | 4 | pH 8.0, 37°C, recombinant enzyme | Mus musculus | methyl 2-amino-3-oxo-3H-phenothiazine-1-carboxylate | |
| 4.1.1.15 | 0.0021 | - |
pH 8.0, 37°C, recombinant enzyme | Rhipicephalus microplus | 6,11-dioxo-5a,6,11,11a-tetrahydronaphtho[2',3':4,5][1,3]thiazolo[3,2-a]pyridin-12-ium | |
| 4.1.1.15 | 0.0022 | - |
pH 8.0, 37°C, recombinant enzyme | Drosophila melanogaster | 6,11-dioxo-5a,6,11,11a-tetrahydronaphtho[2',3':4,5][1,3]thiazolo[3,2-a]pyridin-12-ium | |
| 4.1.1.15 | 0.0022 | - |
pH 8.0, 37°C, recombinant enzyme | Mus musculus | N-[4,7-dioxo-6-(piperidin-1-yl)-4,7-dihydro-2,1,3-benzoxadiazol-5-yl]acetamide | |
| 4.1.1.15 | 0.0022 | - |
pH 8.0, 37°C, recombinant enzyme | Mus musculus | N-[4,7-dioxo-6-(phenylamino)-4,7-dihydro-2,1,3-benzoxadiazol-5-yl]acetamide | |
| 4.1.1.15 | 0.0023 | - |
pH 8.0, 37°C, recombinant enzyme | Mus musculus | 6,11-dioxo-5a,6,11,11a-tetrahydronaphtho[2',3':4,5][1,3]thiazolo[3,2-a]pyridin-12-ium | |
| 4.1.1.15 | 0.0023 | - |
pH 8.0, 37°C, recombinant enzyme | Rhipicephalus microplus | N-[4,7-dioxo-6-(piperidin-1-yl)-4,7-dihydro-2,1,3-benzoxadiazol-5-yl]acetamide | |
| 4.1.1.15 | 0.0026 | - |
pH 8.0, 37°C, recombinant enzyme | Rhipicephalus microplus | 4-[(1,4-dioxo-1,2,3,4-tetrahydronaphthalen-2-yl)sulfanyl]butanoic acid | |
| 4.1.1.15 | 0.0029 | - |
pH 8.0, 37°C, recombinant enzyme | Ctenocephalides felis | 6,11-dioxo-5a,6,11,11a-tetrahydronaphtho[2',3':4,5][1,3]thiazolo[3,2-a]pyridin-12-ium | |
| 4.1.1.15 | 0.0029 | - |
pH 8.0, 37°C, recombinant enzyme | Mus musculus | 4-(morpholin-4-yl)naphthalene-1,2-dione | |
| 4.1.1.15 | 0.003 | - |
pH 8.0, 37°C, recombinant enzyme | Drosophila melanogaster | 4-(piperidin-1-yl)naphthalene-1,2-dione | |
| 4.1.1.15 | 0.003 | - |
pH 8.0, 37°C, recombinant enzyme | Mus musculus | 4-(piperidin-1-yl)naphthalene-1,2-dione | |
| 4.1.1.15 | 0.003 | - |
pH 8.0, 37°C, recombinant enzyme | Drosophila melanogaster | 4-(morpholin-4-yl)naphthalene-1,2-dione | |
| 4.1.1.15 | 0.0033 | - |
pH 8.0, 37°C, recombinant enzyme | Drosophila melanogaster | (5Z)-2-amino-5-(2-nitrobenzylidene)-1,3-thiazol-4(5H)-one | |
| 4.1.1.15 | 0.0033 | - |
pH 8.0, 37°C, recombinant enzyme | Mus musculus | (5Z)-2-amino-5-(2-nitrobenzylidene)-1,3-thiazol-4(5H)-one | |
| 4.1.1.15 | 0.0033 | - |
pH 8.0, 37°C, recombinant enzyme | Mus musculus | 5,6-dichloro-2,1,3-benzothiadiazole-4,7-diol | |
| 4.1.1.15 | 0.0034 | - |
pH 8.0, 37°C, recombinant enzyme | Rhipicephalus microplus | 4-nitro-1,6-dihydrobenzo[1,2-d:3,4-d']bis[1,2,3]triazole | |
| 4.1.1.15 | 0.0034 | - |
pH 8.0, 37°C, recombinant enzyme | Ctenocephalides felis | 4-(morpholin-4-yl)naphthalene-1,2-dione | |
| 4.1.1.15 | 0.0037 | - |
pH 8.0, 37°C, recombinant enzyme | Drosophila melanogaster | naphtho[2',3':4,5]imidazo[1,2-a]pyridine-6,11-dione | |
| 4.1.1.15 | 0.0037 | - |
pH 8.0, 37°C, recombinant enzyme | Ctenocephalides felis | (5Z)-2-amino-5-(2-nitrobenzylidene)-1,3-thiazol-4(5H)-one | |
| 4.1.1.15 | 0.0037 | - |
pH 8.0, 37°C, recombinant enzyme | Drosophila melanogaster | 5,6-dichloro-2,1,3-benzothiadiazole-4,7-diol | |
| 4.1.1.15 | 0.0038 | - |
pH 8.0, 37°C, recombinant enzyme | Drosophila melanogaster | 1,4-dioxo-1,2,3,4-tetrahydronaphthalen-2-yl 2,3,4-tri-O-acetylpentopyranoside | |
| 4.1.1.15 | 0.0038 | - |
pH 8.0, 37°C, recombinant enzyme | Ctenocephalides felis | 4-(piperidin-1-yl)naphthalene-1,2-dione | |
| 4.1.1.15 | 0.0039 | - |
pH 8.0, 37°C, recombinant enzyme | Ctenocephalides felis | naphtho[2',3':4,5]imidazo[1,2-a]pyridine-6,11-dione | |
| 4.1.1.15 | 0.0039 | - |
pH 8.0, 37°C, recombinant enzyme | Rhipicephalus microplus | 4-(morpholin-4-yl)naphthalene-1,2-dione | |
| 4.1.1.15 | 0.004 | - |
pH 8.0, 37°C, recombinant enzyme | Rhipicephalus microplus | 1,4-dioxo-1,2,3,4-tetrahydronaphthalen-2-yl 2,3,4-tri-O-acetylpentopyranoside | |
| 4.1.1.15 | 0.004 | - |
pH 8.0, 37°C, recombinant enzyme | Mus musculus | 1,4-dioxo-1,2,3,4-tetrahydronaphthalen-2-yl 2,3,4-tri-O-acetylpentopyranoside | |
| 4.1.1.15 | 0.0041 | - |
pH 8.0, 37°C, recombinant enzyme | Mus musculus | naphtho[2',3':4,5]imidazo[1,2-a]pyridine-6,11-dione | |
| 4.1.1.15 | 0.0042 | - |
pH 8.0, 37°C, recombinant enzyme | Mus musculus | 2-hydroxy-2-(2-hydroxy-6-oxocyclohex-2-en-1-yl)-1H-indene-1,3(2H)-dione | |
| 4.1.1.15 | 0.0044 | - |
pH 8.0, 37°C, recombinant enzyme | Mus musculus | N-[4,7-dioxo-6-(piperidin-1-yl)-4,7-dihydro-2,1,3-benzoxadiazol-5-yl]acetamide | |
| 4.1.1.15 | 0.0045 | - |
pH 8.0, 37°C, recombinant enzyme | Rhipicephalus microplus | 9H-indeno[1,2-b][1,2,5]oxadiazolo[3,4-e]pyrazin-9-one | |
| 4.1.1.15 | 0.0045 | - |
pH 8.0, 37°C, recombinant enzyme | Mus musculus | 4-(morpholin-4-yl)naphthalene-1,2-dione | |
| 4.1.1.15 | 0.0047 | - |
pH 8.0, 37°C, recombinant enzyme | Drosophila melanogaster | 2-hydroxy-2-(2-hydroxy-6-oxocyclohex-2-en-1-yl)-1H-indene-1,3(2H)-dione | |
| 4.1.1.15 | 0.0047 | - |
pH 8.0, 37°C, recombinant enzyme | Mus musculus | 10H-indeno[2,1-e]tetrazolo[1,5-b][1,2,4]triazin-10-one | |
| 4.1.1.15 | 0.0047 | - |
pH 8.0, 37°C, recombinant enzyme | Mus musculus | 4-(piperidin-1-yl)naphthalene-1,2-dione | |
| 4.1.1.15 | 0.0049 | - |
pH 8.0, 37°C, recombinant enzyme | Mus musculus | biphenyl-3,3'-dicarbaldehyde | |
| 4.1.1.15 | 0.005 | - |
pH 8.0, 37°C, recombinant enzyme | Drosophila melanogaster | methyl 2-[[(2-methylimidazo[1,2-a]pyridin-3-yl)carbonyl]amino]benzoate | |
| 4.1.1.15 | 0.0051 | - |
pH 8.0, 37°C, recombinant enzyme | Rhipicephalus microplus | 2,4-bis[2-(4-hydroxyphenyl)propan-2-yl]phenol | |
| 4.1.1.15 | 0.0052 | - |
pH 8.0, 37°C, recombinant enzyme | Mus musculus | 2-chloro-N-[5-([2-oxo-2-[(4-sulfamoylphenyl)amino]ethyl]sulfanyl)-1,3,4-thiadiazol-2-yl]acetamide | |
| 4.1.1.15 | 0.0053 | - |
pH 8.0, 37°C, recombinant enzyme | Rhipicephalus microplus | biphenyl-3,3'-dicarbaldehyde | |
| 4.1.1.15 | 0.0053 | - |
pH 8.0, 37°C, recombinant enzyme | Ctenocephalides felis | 1,4-dioxo-1,2,3,4-tetrahydronaphthalen-2-yl 2,3,4-tri-O-acetylpentopyranoside | |
| 4.1.1.15 | 0.0053 | - |
pH 8.0, 37°C, recombinant enzyme | Rhipicephalus microplus | 5,6-dichloro-2,1,3-benzothiadiazole-4,7-diol | |
| 4.1.1.15 | 0.0053 | - |
pH 8.0, 37°C, recombinant enzyme | Rhipicephalus microplus | 4-(piperidin-1-yl)naphthalene-1,2-dione | |
| 4.1.1.15 | 0.0055 | - |
pH 8.0, 37°C, recombinant enzyme | Rhipicephalus microplus | 4-nitro-7-[[(1-phenyl-1H-tetrazol-5-yl)sulfanyl]methyl]-2,1,3-benzothiadiazole | |
| 4.1.1.15 | 0.0055 | - |
pH 8.0, 37°C, recombinant enzyme | Ctenocephalides felis | 1-(2-nitrobenzyl)-1H-indole-3-carbaldehyde | |
| 4.1.1.15 | 0.0056 | - |
pH 8.0, 37°C, recombinant enzyme | Ctenocephalides felis | 9H-indeno[1,2-b][1,2,5]oxadiazolo[3,4-e]pyrazin-9-one | |
| 4.1.1.15 | 0.0057 | - |
pH 8.0, 37°C, recombinant enzyme | Mus musculus | 6,11-dioxo-5a,6,11,11a-tetrahydronaphtho[2',3':4,5][1,3]thiazolo[3,2-a]pyridin-12-ium | |
| 4.1.1.15 | 0.0057 | - |
pH 8.0, 37°C, recombinant enzyme | Rhipicephalus microplus | (5Z)-2-amino-5-(2-nitrobenzylidene)-1,3-thiazol-4(5H)-one | |
| 4.1.1.15 | 0.0057 | - |
pH 8.0, 37°C, recombinant enzyme | Ctenocephalides felis | 5,6-dichloro-2,1,3-benzothiadiazole-4,7-diol | |
| 4.1.1.15 | 0.0059 | - |
pH 8.0, 37°C, recombinant enzyme | Ctenocephalides felis | 5-[(E)-[[1-(2-chlorobenzyl)-1H-indol-3-yl]methylidene]amino]-1,3-dihydro-2H-benzimidazol-2-one | |
| 4.1.1.15 | 0.006 | - |
pH 8.0, 37°C, recombinant enzyme | Rhipicephalus microplus | methyl 2-[[(2-methylimidazo[1,2-a]pyridin-3-yl)carbonyl]amino]benzoate | |
| 4.1.1.15 | 0.0062 | - |
pH 8.0, 37°C, recombinant enzyme | Ctenocephalides felis | methyl 2-[[(2-methylimidazo[1,2-a]pyridin-3-yl)carbonyl]amino]benzoate | |
| 4.1.1.15 | 0.0062 | - |
pH 8.0, 37°C, recombinant enzyme | Ctenocephalides felis | biphenyl-3,3'-dicarbaldehyde | |
| 4.1.1.15 | 0.0062 | - |
pH 8.0, 37°C, recombinant enzyme | Ctenocephalides felis | 2-hydroxy-2-(2-hydroxy-6-oxocyclohex-2-en-1-yl)-1H-indene-1,3(2H)-dione | |
| 4.1.1.15 | 0.0063 | - |
pH 8.0, 37°C, recombinant enzyme | Drosophila melanogaster | biphenyl-3,3'-dicarbaldehyde | |
| 4.1.1.15 | 0.0063 | - |
pH 8.0, 37°C, recombinant enzyme | Rhipicephalus microplus | 3-[(E)-(2,6-difluorobenzylidene)amino]-2-thioxo-1,3-thiazolidin-4-one | |
| 4.1.1.15 | 0.0063 | - |
pH 8.0, 37°C, recombinant enzyme | Rhipicephalus microplus | 5-[(E)-[[1-(2-chlorobenzyl)-1H-indol-3-yl]methylidene]amino]-1,3-dihydro-2H-benzimidazol-2-one | |
| 4.1.1.15 | 0.0064 | - |
pH 8.0, 37°C, recombinant enzyme | Mus musculus | 4-[(1,4-dioxo-1,2,3,4-tetrahydronaphthalen-2-yl)sulfanyl]butanoic acid | |
| 4.1.1.15 | 0.0064 | - |
pH 8.0, 37°C, recombinant enzyme | Mus musculus | 3-[(E)-(2,6-difluorobenzylidene)amino]-2-thioxo-1,3-thiazolidin-4-one | |
| 4.1.1.15 | 0.0065 | - |
pH 8.0, 37°C, recombinant enzyme | Mus musculus | methyl 2-[[(2-methylimidazo[1,2-a]pyridin-3-yl)carbonyl]amino]benzoate | |
| 4.1.1.15 | 0.0065 | - |
pH 8.0, 37°C, recombinant enzyme | Mus musculus | 5-[(E)-[[1-(2-chlorobenzyl)-1H-indol-3-yl]methylidene]amino]-1,3-dihydro-2H-benzimidazol-2-one | |
| 4.1.1.15 | 0.0066 | - |
pH 8.0, 37°C, recombinant enzyme | Drosophila melanogaster | 5-[(E)-[[1-(2-chlorobenzyl)-1H-indol-3-yl]methylidene]amino]-1,3-dihydro-2H-benzimidazol-2-one | |
| 4.1.1.15 | 0.0067 | - |
pH 8.0, 37°C, recombinant enzyme | Drosophila melanogaster | 4-[(1,4-dioxo-1,2,3,4-tetrahydronaphthalen-2-yl)sulfanyl]butanoic acid | |
| 4.1.1.15 | 0.0069 | - |
pH 8.0, 37°C, recombinant enzyme | Ctenocephalides felis | 4-[(1,4-dioxo-1,2,3,4-tetrahydronaphthalen-2-yl)sulfanyl]butanoic acid | |
| 4.1.1.15 | 0.0069 | - |
pH 8.0, 37°C, recombinant enzyme | Rhipicephalus microplus | 2-hydroxy-2-(2-hydroxy-6-oxocyclohex-2-en-1-yl)-1H-indene-1,3(2H)-dione | |
| 4.1.1.15 | 0.0069 | - |
pH 8.0, 37°C, recombinant enzyme | Mus musculus | 1-(2-nitrobenzyl)-1H-indole-3-carbaldehyde | |
| 4.1.1.15 | 0.0069 | - |
pH 8.0, 37°C, recombinant enzyme | Mus musculus | 5-[(E)-benzylideneamino]-6-[(2-hydroxyethyl)amino]pyrimidine-2,4(1H,3H)-dione | |
| 4.1.1.15 | 0.0072 | - |
pH 8.0, 37°C, recombinant enzyme | Mus musculus | 4,4'-(phenylmethanediyl)bis[2-(4-chlorophenyl)-5-methyl-2,4-dihydro-3H-pyrazol-3-one] | |
| 4.1.1.15 | 0.0073 | - |
pH 8.0, 37°C, recombinant enzyme | Rhipicephalus microplus | naphtho[2',3':4,5]imidazo[1,2-a]pyridine-6,11-dione | |
| 4.1.1.15 | 0.0073 | - |
pH 8.0, 37°C, recombinant enzyme | Mus musculus | 2-(benzylsulfanyl)-3-(morpholin-4-yl)-2,3-dihydronaphthalene-1,4-dione | |
| 4.1.1.15 | 0.0075 | - |
pH 8.0, 37°C, recombinant enzyme | Rhipicephalus microplus | 2-thioxo-3-[(E)-(3,3,5-trimethylcyclohexylidene)amino]-1,3-thiazolidin-4-one | |
| 4.1.1.15 | 0.0076 | - |
pH 8.0, 37°C, recombinant enzyme | Mus musculus | N-(2-hydroxy-1,3-dioxo-2,3-dihydro-1H-inden-2-yl)benzamide | |
| 4.1.1.15 | 0.0076 | - |
pH 8.0, 37°C, recombinant enzyme | Drosophila melanogaster | 1-(2-nitrobenzyl)-1H-indole-3-carbaldehyde | |
| 4.1.1.15 | 0.0077 | - |
pH 8.0, 37°C, recombinant enzyme | Mus musculus | 4-nitro-1,6-dihydrobenzo[1,2-d:3,4-d']bis[1,2,3]triazole | |
| 4.1.1.15 | 0.0077 | - |
pH 8.0, 37°C, recombinant enzyme | Drosophila melanogaster | 5-[(E)-benzylideneamino]-6-[(2-hydroxyethyl)amino]pyrimidine-2,4(1H,3H)-dione | |
| 4.1.1.15 | 0.0079 | - |
pH 8.0, 37°C, recombinant enzyme | Mus musculus | 3-[(E)-(2,6-difluorobenzylidene)amino]-2-thioxo-1,3-thiazolidin-4-one | |
| 4.1.1.15 | 0.008 | - |
pH 8.0, 37°C, recombinant enzyme | Rhipicephalus microplus | 1-(2-nitrobenzyl)-1H-indole-3-carbaldehyde | |
| 4.1.1.15 | 0.0082 | - |
pH 8.0, 37°C, recombinant enzyme | Rhipicephalus microplus | N-(2-hydroxy-1,3-dioxo-2,3-dihydro-1H-inden-2-yl)benzamide | |
| 4.1.1.15 | 0.0082 | - |
pH 8.0, 37°C, recombinant enzyme | Ctenocephalides felis | 2-[(3-formyl-1H-indol-1-yl)methyl]benzonitrile | |
| 4.1.1.15 | 0.0083 | - |
pH 8.0, 37°C, recombinant enzyme | Mus musculus | 5,6-dichloro-2,1,3-benzothiadiazole-4,7-diol | |
| 4.1.1.15 | 0.0087 | - |
pH 8.0, 37°C, recombinant enzyme | Mus musculus | 2-chloro-N-[5-([2-oxo-2-[(4-sulfamoylphenyl)amino]ethyl]sulfanyl)-1,3,4-thiadiazol-2-yl]acetamide | |
| 4.1.1.15 | 0.0087 | - |
pH 8.0, 37°C, recombinant enzyme | Ctenocephalides felis | 5-[(E)-benzylideneamino]-6-[(2-hydroxyethyl)amino]pyrimidine-2,4(1H,3H)-dione | |
| 4.1.1.15 | 0.0089 | - |
pH 8.0, 37°C, recombinant enzyme | Drosophila melanogaster | 2-(benzylsulfanyl)-3-(morpholin-4-yl)-2,3-dihydronaphthalene-1,4-dione | |
| 4.1.1.15 | 0.0089 | - |
pH 8.0, 37°C, recombinant enzyme | Drosophila melanogaster | 9H-indeno[1,2-b][1,2,5]oxadiazolo[3,4-e]pyrazin-9-one | |
| 4.1.1.15 | 0.0089 | - |
pH 8.0, 37°C, recombinant enzyme | Mus musculus | 2-[(3-formyl-1H-indol-1-yl)methyl]benzonitrile | |
| 4.1.1.15 | 0.0091 | - |
pH 8.0, 37°C, recombinant enzyme | Ctenocephalides felis | N-(2-hydroxy-1,3-dioxo-2,3-dihydro-1H-inden-2-yl)benzamide | |
| 4.1.1.15 | 0.01 | - |
pH 8.0, 37°C, recombinant enzyme | Mus musculus | 2-thioxo-3-[(E)-(3,3,5-trimethylcyclohexylidene)amino]-1,3-thiazolidin-4-one | |
| 4.1.1.15 | 0.0104 | - |
pH 8.0, 37°C, recombinant enzyme | Mus musculus | 5-[(E)-benzylideneamino]-6-[(2-hydroxyethyl)amino]pyrimidine-2,4(1H,3H)-dione | |
| 4.1.1.15 | 0.0104 | - |
pH 8.0, 37°C, recombinant enzyme | Rhipicephalus microplus | 5-[(E)-benzylideneamino]-6-[(2-hydroxyethyl)amino]pyrimidine-2,4(1H,3H)-dione | |
| 4.1.1.15 | 0.0105 | - |
pH 8.0, 37°C, recombinant enzyme | Drosophila melanogaster | N-(2-hydroxy-1,3-dioxo-2,3-dihydro-1H-inden-2-yl)benzamide | |
| 4.1.1.15 | 0.0108 | - |
pH 8.0, 37°C, recombinant enzyme | Mus musculus | 2-hydroxy-2-(2-hydroxy-6-oxocyclohex-2-en-1-yl)-1H-indene-1,3(2H)-dione | |
| 4.1.1.15 | 0.0109 | - |
pH 8.0, 37°C, recombinant enzyme | Drosophila melanogaster | 3-[(E)-(2,6-difluorobenzylidene)amino]-2-thioxo-1,3-thiazolidin-4-one | |
| 4.1.1.15 | 0.0112 | - |
pH 8.0, 37°C, recombinant enzyme | Mus musculus | 4-[(1,4-dioxo-1,2,3,4-tetrahydronaphthalen-2-yl)sulfanyl]butanoic acid | |
| 4.1.1.15 | 0.0112 | - |
pH 8.0, 37°C, recombinant enzyme | Rhipicephalus microplus | 2-(benzylsulfanyl)-3-(morpholin-4-yl)-2,3-dihydronaphthalene-1,4-dione | |
| 4.1.1.15 | 0.0115 | - |
pH 8.0, 37°C, recombinant enzyme | Ctenocephalides felis | 2-(benzylsulfanyl)-3-(morpholin-4-yl)-2,3-dihydronaphthalene-1,4-dione | |
| 4.1.1.15 | 0.012 | - |
pH 8.0, 37°C, recombinant enzyme | Mus musculus | 1,4-dioxo-1,2,3,4-tetrahydronaphthalen-2-yl 2,3,4-tri-O-acetylpentopyranoside | |
| 4.1.1.15 | 0.012 | - |
pH 8.0, 37°C, recombinant enzyme | Mus musculus | 4,4'-(phenylmethanediyl)bis[2-(4-chlorophenyl)-5-methyl-2,4-dihydro-3H-pyrazol-3-one] | |
| 4.1.1.15 | 0.0122 | - |
pH 8.0, 37°C, recombinant enzyme | Ctenocephalides felis | 3-[(E)-(2,6-difluorobenzylidene)amino]-2-thioxo-1,3-thiazolidin-4-one | |
| 4.1.1.15 | 0.0122 | - |
pH 8.0, 37°C, recombinant enzyme | Drosophila melanogaster | 5-[[5-hydroxy-3-methyl-1-(4-methylphenyl)-1H-pyrazol-4-yl]methylidene]-1,3-diphenyl-2-thioxodihydropyrimidine-4,6(1H,5H)-dione | |
| 4.1.1.15 | 0.0123 | - |
pH 8.0, 37°C, recombinant enzyme | Mus musculus | (4Z,7E)-N,N'-dihydroxy-2,2-dimethyl-5,6-dihydro-2H-benzimidazole-4,7-diimine | |
| 4.1.1.15 | 0.0125 | - |
pH 8.0, 37°C, recombinant enzyme | Mus musculus | methyl 2-[[(2-methylimidazo[1,2-a]pyridin-3-yl)carbonyl]amino]benzoate | |
| 4.1.1.15 | 0.0126 | - |
pH 8.0, 37°C, recombinant enzyme | Mus musculus | 2-[(3-formyl-1H-indol-1-yl)methyl]benzonitrile | |
| 4.1.1.15 | 0.0127 | - |
pH 8.0, 37°C, recombinant enzyme | Mus musculus | 2-thioxo-3-[(E)-(3,3,5-trimethylcyclohexylidene)amino]-1,3-thiazolidin-4-one | |
| 4.1.1.15 | 0.0129 | - |
pH 8.0, 37°C, recombinant enzyme | Mus musculus | 5-[(E)-[[1-(2-chlorobenzyl)-1H-indol-3-yl]methylidene]amino]-1,3-dihydro-2H-benzimidazol-2-one | |
| 4.1.1.15 | 0.013 | - |
pH 8.0, 37°C, recombinant enzyme | Mus musculus | 4,4'-[(4-hydroxyphenyl)methanediyl]bis(2-heptyl-5-methyl-2,4-dihydro-3H-pyrazol-3-one) | |
| 4.1.1.15 | 0.0135 | - |
pH 8.0, 37°C, recombinant enzyme | Rhipicephalus microplus | (4Z,7E)-N,N'-dihydroxy-2,2-dimethyl-5,6-dihydro-2H-benzimidazole-4,7-diimine | |
| 4.1.1.15 | 0.0138 | - |
pH 8.0, 37°C, recombinant enzyme | Mus musculus | 4,4'-[(4-hydroxyphenyl)methanediyl]bis(2-heptyl-5-methyl-2,4-dihydro-3H-pyrazol-3-one) | |
| 4.1.1.15 | 0.0138 | - |
pH 8.0, 37°C, recombinant enzyme | Drosophila melanogaster | 2-[(3-formyl-1H-indol-1-yl)methyl]benzonitrile | |
| 4.1.1.15 | 0.0139 | - |
pH 8.0, 37°C, recombinant enzyme | Ctenocephalides felis | 2-thioxo-3-[(E)-(3,3,5-trimethylcyclohexylidene)amino]-1,3-thiazolidin-4-one | |
| 4.1.1.15 | 0.014 | - |
pH 8.0, 37°C, recombinant enzyme | Drosophila melanogaster | 2-thioxo-3-[(E)-(3,3,5-trimethylcyclohexylidene)amino]-1,3-thiazolidin-4-one | |
| 4.1.1.15 | 0.014 | - |
pH 8.0, 37°C, recombinant enzyme | Rhipicephalus microplus | 2-[(3-formyl-1H-indol-1-yl)methyl]benzonitrile | |
| 4.1.1.15 | 0.0142 | - |
pH 8.0, 37°C, recombinant enzyme | Mus musculus | 1-(2-nitrobenzyl)-1H-indole-3-carbaldehyde | |
| 4.1.1.15 | 0.0143 | - |
pH 8.0, 37°C, recombinant enzyme | Mus musculus | 9H-indeno[1,2-b][1,2,5]oxadiazolo[3,4-e]pyrazin-9-one | |
| 4.1.1.15 | 0.0144 | - |
pH 8.0, 37°C, recombinant enzyme | Ctenocephalides felis | 5-[[5-hydroxy-3-methyl-1-(4-methylphenyl)-1H-pyrazol-4-yl]methylidene]-1,3-diphenyl-2-thioxodihydropyrimidine-4,6(1H,5H)-dione | |
| 4.1.1.15 | 0.0148 | - |
pH 8.0, 37°C, recombinant enzyme | Rhipicephalus microplus | 3,3'-(4H-1,2,4-triazole-3,5-diyl)bis(4-nitro-1,2,5-oxadiazole) | |
| 4.1.1.15 | 0.0149 | - |
pH 8.0, 37°C, recombinant enzyme | Rhipicephalus microplus | 5-[[5-hydroxy-3-methyl-1-(4-methylphenyl)-1H-pyrazol-4-yl]methylidene]-1,3-diphenyl-2-thioxodihydropyrimidine-4,6(1H,5H)-dione | |
| 4.1.1.15 | 0.0162 | - |
pH 8.0, 37°C, recombinant enzyme | Ctenocephalides felis | 2-chloro-N-[5-([2-oxo-2-[(4-sulfamoylphenyl)amino]ethyl]sulfanyl)-1,3,4-thiadiazol-2-yl]acetamide | |
| 4.1.1.15 | 0.0164 | - |
pH 8.0, 37°C, recombinant enzyme | Mus musculus | N-(2-hydroxy-1,3-dioxo-2,3-dihydro-1H-inden-2-yl)benzamide | |
| 4.1.1.15 | 0.0165 | - |
pH 8.0, 37°C, recombinant enzyme | Ctenocephalides felis | 2-[(2-chloro-5-nitrobenzoyl)amino]-5-iodobenzoic acid | |
| 4.1.1.15 | 0.0173 | - |
pH 8.0, 37°C, recombinant enzyme | Ctenocephalides felis | 4,4'-[(4-hydroxyphenyl)methanediyl]bis(2-heptyl-5-methyl-2,4-dihydro-3H-pyrazol-3-one) | |
| 4.1.1.15 | 0.0188 | - |
pH 8.0, 37°C, recombinant enzyme | Drosophila melanogaster | 4,4'-[(4-hydroxyphenyl)methanediyl]bis(2-heptyl-5-methyl-2,4-dihydro-3H-pyrazol-3-one) | |
| 4.1.1.15 | 0.0196 | - |
pH 8.0, 37°C, recombinant enzyme | Ctenocephalides felis | 3,3'-(4H-1,2,4-triazole-3,5-diyl)bis(4-nitro-1,2,5-oxadiazole) | |
| 4.1.1.15 | 0.0202 | - |
pH 8.0, 37°C, recombinant enzyme | Rhipicephalus microplus | 3-[(2E)-2-[1-(3,4-dimethoxyphenyl)ethylidene]hydrazinyl]benzoic acid | |
| 4.1.1.15 | 0.0209 | - |
pH 8.0, 37°C, recombinant enzyme | Drosophila melanogaster | 4-nitro-1,6-dihydrobenzo[1,2-d:3,4-d']bis[1,2,3]triazole | |
| 4.1.1.15 | 0.0209 | - |
pH 8.0, 37°C, recombinant enzyme | Mus musculus | 2-(benzylsulfanyl)-3-(morpholin-4-yl)-2,3-dihydronaphthalene-1,4-dione | |
| 4.1.1.15 | 0.0211 | - |
pH 8.0, 37°C, recombinant enzyme | Ctenocephalides felis | 4-nitro-1,6-dihydrobenzo[1,2-d:3,4-d']bis[1,2,3]triazole | |
| 4.1.1.15 | 0.0212 | - |
pH 8.0, 37°C, recombinant enzyme | Drosophila melanogaster | 3,3'-(4H-1,2,4-triazole-3,5-diyl)bis(4-nitro-1,2,5-oxadiazole) | |
| 4.1.1.15 | 0.0218 | - |
pH 8.0, 37°C, recombinant enzyme | Ctenocephalides felis | 4,4'-(phenylmethanediyl)bis[2-(4-chlorophenyl)-5-methyl-2,4-dihydro-3H-pyrazol-3-one] | |
| 4.1.1.15 | 0.0226 | - |
pH 8.0, 37°C, recombinant enzyme | Rhipicephalus microplus | 4,4'-[(4-hydroxyphenyl)methanediyl]bis(2-heptyl-5-methyl-2,4-dihydro-3H-pyrazol-3-one) | |
| 4.1.1.15 | 0.0244 | - |
pH 8.0, 37°C, recombinant enzyme | Drosophila melanogaster | [(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)oxy]acetic acid | |
| 4.1.1.15 | 0.0257 | - |
pH 8.0, 37°C, recombinant enzyme | Ctenocephalides felis | [(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)oxy]acetic acid | |
| 4.1.1.15 | 0.0266 | - |
pH 8.0, 37°C, recombinant enzyme | Mus musculus | (4Z,7E)-N,N'-dihydroxy-2,2-dimethyl-5,6-dihydro-2H-benzimidazole-4,7-diimine | |
| 4.1.1.15 | 0.0269 | - |
pH 8.0, 37°C, recombinant enzyme | Drosophila melanogaster | 4,4'-(phenylmethanediyl)bis[2-(4-chlorophenyl)-5-methyl-2,4-dihydro-3H-pyrazol-3-one] | |
| 4.1.1.15 | 0.0274 | - |
pH 8.0, 37°C, recombinant enzyme | Ctenocephalides felis | (4Z,7E)-N,N'-dihydroxy-2,2-dimethyl-5,6-dihydro-2H-benzimidazole-4,7-diimine | |
| 4.1.1.15 | 0.0284 | - |
pH 8.0, 37°C, recombinant enzyme | Rhipicephalus microplus | [(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)oxy]acetic acid | |
| 4.1.1.15 | 0.0284 | - |
pH 8.0, 37°C, recombinant enzyme | Drosophila melanogaster | 2-chloro-N-[5-([2-oxo-2-[(4-sulfamoylphenyl)amino]ethyl]sulfanyl)-1,3,4-thiadiazol-2-yl]acetamide | |
| 4.1.1.15 | 0.03 | - |
pH 8.0, 37°C, recombinant enzyme | Drosophila melanogaster | (4Z,7E)-N,N'-dihydroxy-2,2-dimethyl-5,6-dihydro-2H-benzimidazole-4,7-diimine | |
| 4.1.1.15 | 0.0418 | - |
pH 8.0, 37°C, recombinant enzyme | Mus musculus | (5Z)-2-amino-5-(2-nitrobenzylidene)-1,3-thiazol-4(5H)-one | |
| 4.1.1.15 | 0.0558 | - |
pH 8.0, 37°C, recombinant enzyme | Mus musculus | 5-[[5-hydroxy-3-methyl-1-(4-methylphenyl)-1H-pyrazol-4-yl]methylidene]-1,3-diphenyl-2-thioxodihydropyrimidine-4,6(1H,5H)-dione | |
| 4.1.1.15 | 0.0591 | - |
pH 8.0, 37°C, recombinant enzyme | Mus musculus | naphtho[2',3':4,5]imidazo[1,2-a]pyridine-6,11-dione | |
| 4.1.1.15 | 0.0593 | - |
pH 8.0, 37°C, recombinant enzyme | Mus musculus | 5-[[5-hydroxy-3-methyl-1-(4-methylphenyl)-1H-pyrazol-4-yl]methylidene]-1,3-diphenyl-2-thioxodihydropyrimidine-4,6(1H,5H)-dione | |
| 4.1.1.15 | 0.065 | - |
pH 8.0, 37°C, recombinant enzyme | Mus musculus | 4-nitro-1,6-dihydrobenzo[1,2-d:3,4-d']bis[1,2,3]triazole | |
| 4.1.1.15 | 0.0714 | - |
pH 8.0, 37°C, recombinant enzyme | Drosophila melanogaster | 2-[(2-chloro-5-nitrobenzoyl)amino]-5-iodobenzoic acid | |
| 4.1.1.15 | 0.0777 | - |
pH 8.0, 37°C, recombinant enzyme | Mus musculus | 2,4-bis[2-(4-hydroxyphenyl)propan-2-yl]phenol | |
| 4.1.1.15 | 0.0845 | - |
pH 8.0, 37°C, recombinant enzyme | Mus musculus | 2-[(2-chloro-5-nitrobenzoyl)amino]-5-iodobenzoic acid | |
| 4.1.1.15 | 0.0912 | - |
pH 8.0, 37°C, recombinant enzyme | Ctenocephalides felis | 4-nitro-7-[[(1-phenyl-1H-tetrazol-5-yl)sulfanyl]methyl]-2,1,3-benzothiadiazole | |
| 4.1.1.15 | 0.0981 | - |
pH 8.0, 37°C, recombinant enzyme | Drosophila melanogaster | 4-nitro-7-[[(1-phenyl-1H-tetrazol-5-yl)sulfanyl]methyl]-2,1,3-benzothiadiazole | |
| 4.1.1.15 | 0.099 | - |
pH 8.0, 37°C, recombinant enzyme | Rhipicephalus microplus | 4,4'-(phenylmethanediyl)bis[2-(4-chlorophenyl)-5-methyl-2,4-dihydro-3H-pyrazol-3-one] | |
| 4.1.1.15 | 0.1 | - |
above, pH 8.0, 37°C, recombinant enzyme | Mus musculus | 4-nitro-7-[[(1-phenyl-1H-tetrazol-5-yl)sulfanyl]methyl]-2,1,3-benzothiadiazole | |
| 4.1.1.15 | 0.1 | - |
above, pH 8.0, 37°C, recombinant enzyme | Mus musculus | 2,4-bis[2-(4-hydroxyphenyl)propan-2-yl]phenol | |
| 4.1.1.15 | 0.1 | - |
above, pH 8.0, 37°C, recombinant enzyme | Ctenocephalides felis | 2,4-bis[2-(4-hydroxyphenyl)propan-2-yl]phenol | |
| 4.1.1.15 | 0.1 | - |
above, pH 8.0, 37°C, recombinant enzyme | Drosophila melanogaster | 2,4-bis[2-(4-hydroxyphenyl)propan-2-yl]phenol | |
| 4.1.1.15 | 0.1 | - |
above, pH 8.0, 37°C, recombinant enzyme | Mus musculus | 3-[(2E)-2-[1-(3,4-dimethoxyphenyl)ethylidene]hydrazinyl]benzoic acid | |
| 4.1.1.15 | 0.1 | - |
above, pH 8.0, 37°C, recombinant enzyme | Ctenocephalides felis | 3-[(2E)-2-[1-(3,4-dimethoxyphenyl)ethylidene]hydrazinyl]benzoic acid | |
| 4.1.1.15 | 0.1 | - |
above, pH 8.0, 37°C, recombinant enzyme | Drosophila melanogaster | 3-[(2E)-2-[1-(3,4-dimethoxyphenyl)ethylidene]hydrazinyl]benzoic acid | |
| 4.1.1.15 | 0.1 | - |
above, pH 8.0, 37°C, recombinant enzyme | Mus musculus | [(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)oxy]acetic acid | |
| 4.1.1.15 | 0.1 | - |
above, pH 8.0, 37°C, recombinant enzyme | Rhipicephalus microplus | 2-chloro-N-[5-([2-oxo-2-[(4-sulfamoylphenyl)amino]ethyl]sulfanyl)-1,3,4-thiadiazol-2-yl]acetamide | |
| 4.1.1.15 | 0.1 | - |
above, pH 8.0, 37°C, recombinant enzyme | Mus musculus | 9H-indeno[1,2-b][1,2,5]oxadiazolo[3,4-e]pyrazin-9-one | |
| 4.1.1.15 | 0.1 | - |
above, pH 8.0, 37°C, recombinant enzyme | Mus musculus | 2-[(2-chloro-5-nitrobenzoyl)amino]-5-iodobenzoic acid | |
| 4.1.1.15 | 0.1 | - |
above, pH 8.0, 37°C, recombinant enzyme | Rhipicephalus microplus | 2-[(2-chloro-5-nitrobenzoyl)amino]-5-iodobenzoic acid | |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
