EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
1.14.15.14 | 0.021 | - |
farnesol | at pH 7.5 and 25°C | Mycobacterium tuberculosis | |
1.14.15.14 | 0.036 | - |
cholest-4-en-3-one | at pH 7.5 and 25°C | Mycobacterium tuberculosis |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.14.15.14 | a methyl-branched lipid + O2 + reduced ferredoxin [iron-sulfur] cluster + H+ | Mycobacterium tuberculosis | the enzyme uses spinach NAD(P)H-dependent ferredoxin reductase and the [2Fe-2S] iron-sulfur protein ferredoxin as an electron transport system | an omega-hydroxy-methyl-branched lipid + H2O + oxidized ferredoxin [iron-sulfur] cluster | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.14.15.14 | Mycobacterium tuberculosis | - |
- |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.14.15.14 | a methyl-branched lipid + O2 + reduced ferredoxin [iron-sulfur] cluster + H+ | the enzyme uses spinach NAD(P)H-dependent ferredoxin reductase and the [2Fe-2S] iron-sulfur protein ferredoxin as an electron transport system | Mycobacterium tuberculosis | an omega-hydroxy-methyl-branched lipid + H2O + oxidized ferredoxin [iron-sulfur] cluster | - |
? | |
1.14.15.14 | cholest-4-en-3-one + O2 + reduced ferredoxin [iron-sulfur] cluster + H+ | - |
Mycobacterium tuberculosis | ? + H2O + oxidized ferredoxin [iron-sulfur] cluster | - |
? | |
1.14.15.14 | farnesol + O2 + reduced ferredoxin [iron-sulfur] cluster + H+ | - |
Mycobacterium tuberculosis | ? + H2O + oxidized ferredoxin [iron-sulfur] cluster | - |
? | |
1.14.15.14 | geranylgeraniol + O2 + reduced ferredoxin [iron-sulfur] cluster + H+ | - |
Mycobacterium tuberculosis | ? + H2O + oxidized ferredoxin [iron-sulfur] cluster | - |
? | |
1.14.15.14 | additional information | the enzyme shows very low activity towards palmitic acid and 15-methyl-palmitic acid | Mycobacterium tuberculosis | ? | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
1.14.15.14 | CYP124 | - |
Mycobacterium tuberculosis |
EC Number | Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
1.14.15.14 | 0.195 | - |
cholest-4-en-3-one | at pH 7.5 and 25°C | Mycobacterium tuberculosis | |
1.14.15.14 | 0.258 | - |
farnesol | at pH 7.5 and 25°C | Mycobacterium tuberculosis |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
1.14.15.14 | NADPH | - |
Mycobacterium tuberculosis |