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Literature summary extracted from

  • Beaupre, B.A.; Roman, J.V.; Hoag, M.R.; Meneely, K.M.; Silvaggi, N.R.; Lamb, A.L.; Moran, G.R.
    Ligand binding phenomena that pertain to the metabolic function of renalase (2016), Arch. Biochem. Biophys., 612, 46-56 .
    View publication on PubMedView publication on EuropePMC

Activating Compound

EC Number Activating Compound Comment Organism Structure
1.6.3.5 ADP
-
 Pseudomonas savastanoi pv. phaseolicola

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.6.3.5 4-dihydronicotinamide mononucleotide
-
 Pseudomonas savastanoi pv. phaseolicola
1.6.3.5 4-dihydronicotinamide riboside
-
 Pseudomonas savastanoi pv. phaseolicola
1.6.3.5 ADP
-
 Pseudomonas savastanoi pv. phaseolicola
1.6.3.5 ADP-ribose
-
 Pseudomonas savastanoi pv. phaseolicola
1.6.3.5 AMP
-
 Pseudomonas savastanoi pv. phaseolicola
1.6.3.5 beta-NADP+
-
 Pseudomonas savastanoi pv. phaseolicola
1.6.3.5 methyl nicotinamide
-
 Pseudomonas savastanoi pv. phaseolicola
1.6.3.5 nicotinamide
-
 Pseudomonas savastanoi pv. phaseolicola
1.6.3.5 nicotinamide mononucleotide
-
 Pseudomonas savastanoi pv. phaseolicola
1.6.3.5 nicotinamide riboside
-
 Pseudomonas savastanoi pv. phaseolicola

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.6.3.5 1,2-dihydro-beta-NADH + H+ + O2 Pseudomonas savastanoi pv. phaseolicola
-
 beta-NAD+ + H2O2
-
 ?
1.6.3.5 1,2-dihydro-beta-NADH + H+ + O2 Pseudomonas savastanoi pv. phaseolicola 1448A
-
 beta-NAD+ + H2O2
-
 ?
1.6.3.5 1,2-dihydro-beta-NADPH + H+ + O2 Pseudomonas savastanoi pv. phaseolicola
-
 beta-NADP+ + H2O2
-
 ?
1.6.3.5 1,2-dihydro-beta-NADPH + H+ + O2 Pseudomonas savastanoi pv. phaseolicola 1448A
-
 beta-NADP+ + H2O2
-
 ?
1.6.3.5 1,6-dihydro-beta-NADH + H+ + O2 Pseudomonas savastanoi pv. phaseolicola
-
 beta-NAD+ + H2O2
-
 ?
1.6.3.5 1,6-dihydro-beta-NADH + H+ + O2 Pseudomonas savastanoi pv. phaseolicola 1448A
-
 beta-NAD+ + H2O2
-
 ?
1.6.3.5 1,6-dihydro-beta-NADPH + H+ + O2 Pseudomonas savastanoi pv. phaseolicola
-
 beta-NADP+ + H2O2
-
 ?
1.6.3.5 1,6-dihydro-beta-NADPH + H+ + O2 Pseudomonas savastanoi pv. phaseolicola 1448A
-
 beta-NADP+ + H2O2
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.6.3.5 Pseudomonas savastanoi pv. phaseolicola Q48MT7
-
-
1.6.3.5 Pseudomonas savastanoi pv. phaseolicola 1448A Q48MT7
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.6.3.5 1,2-dihydro-beta-NADH + H+ + O2
-
 Pseudomonas savastanoi pv. phaseolicola beta-NAD+ + H2O2
-
 ?
1.6.3.5 1,2-dihydro-beta-NADH + H+ + O2
-
 Pseudomonas savastanoi pv. phaseolicola 1448A beta-NAD+ + H2O2
-
 ?
1.6.3.5 1,2-dihydro-beta-NADPH + H+ + O2
-
 Pseudomonas savastanoi pv. phaseolicola beta-NADP+ + H2O2
-
 ?
1.6.3.5 1,2-dihydro-beta-NADPH + H+ + O2
-
 Pseudomonas savastanoi pv. phaseolicola 1448A beta-NADP+ + H2O2
-
 ?
1.6.3.5 1,6-dihydro-beta-NADH + H+ + O2
-
 Pseudomonas savastanoi pv. phaseolicola beta-NAD+ + H2O2
-
 ?
1.6.3.5 1,6-dihydro-beta-NADH + H+ + O2
-
 Pseudomonas savastanoi pv. phaseolicola 1448A beta-NAD+ + H2O2
-
 ?
1.6.3.5 1,6-dihydro-beta-NADPH + H+ + O2
-
 Pseudomonas savastanoi pv. phaseolicola beta-NADP+ + H2O2
-
 ?
1.6.3.5 1,6-dihydro-beta-NADPH + H+ + O2
-
 Pseudomonas savastanoi pv. phaseolicola 1448A beta-NADP+ + H2O2
-
 ?
1.6.3.5 2-dihydronicotinamide adenine dinucleotide phosphate + O2
-
 Pseudomonas savastanoi pv. phaseolicola ?
-
 ?
1.6.3.5 2-dihydronicotinamide riboside + O2
-
 Pseudomonas savastanoi pv. phaseolicola ?
-
 ?
1.6.3.5 6-dihydronicotinamide adenine dinucleotide phosphate + O2
-
 Pseudomonas savastanoi pv. phaseolicola ?
-
 ?
1.6.3.5 6-dihydronicotinamide riboside + O2
-
 Pseudomonas savastanoi pv. phaseolicola ?
-
 ?
1.6.3.5 alpha-NADH + H+ + O2
-
 Pseudomonas savastanoi pv. phaseolicola beta-NAD+ + H2O2
-
 ?
1.6.3.5 alpha-NADPH + H+ + O2
-
 Pseudomonas savastanoi pv. phaseolicola beta-NADP+ + H2O2
-
 ?
1.6.3.5 additional information renalase exhibits a preference for substrates derived from beta-NAD+ over those derived from beta-NADP+ Pseudomonas savastanoi pv. phaseolicola ?
-
 ?
1.6.3.5 additional information renalase exhibits a preference for substrates derived from beta-NAD+ over those derived from beta-NADP+ Pseudomonas savastanoi pv. phaseolicola 1448A ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.6.3.5 REN
-
 Pseudomonas savastanoi pv. phaseolicola

Cofactor

EC Number Cofactor Comment Organism Structure
1.6.3.5 FAD
-
 Pseudomonas savastanoi pv. phaseolicola
1.6.3.5 NADH
-
 Pseudomonas savastanoi pv. phaseolicola
1.6.3.5 NADPH
-
 Pseudomonas savastanoi pv. phaseolicola