Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Bojarova, P.; Williams, S.
    Sulfotransferases, sulfatases and formylglycine-generating enzymes a sulfation fascination (2008), Curr. Opin. Chem. Biol., 12, 573-581 .
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.8.3.7 a [sulfatase]-L-cysteine + O2 + a thiol Homo sapiens
-
 a [sulfatase]-3-oxo-L-alanine + hydrogen sulfide + a disulfide + H2O
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.8.3.7 Homo sapiens
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.8.3.7 a [sulfatase]-L-cysteine + O2 + a thiol
-
 Homo sapiens a [sulfatase]-3-oxo-L-alanine + hydrogen sulfide + a disulfide + H2O
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.8.3.7 FGE
-
 Homo sapiens
1.8.3.7 SUMF1
-
 Homo sapiens

Cofactor

EC Number Cofactor Comment Organism Structure
1.8.3.7 additional information the enzyme is cofactor-independent Homo sapiens

General Information

EC Number General Information Comment Organism
1.8.3.7 malfunction enzyme dysfunction causes a lysosomal storage disorder known as multiple sulfatase deficiency, where all sulfatases either lack or suffer from a severely reduced, catalytic activity caused by incomplete generation of formylglycine Homo sapiens