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Literature summary extracted from

  • Martin, C.; Tjallinks, G.; Trajkovic, M.; Fraaije, M.W.
    Facile stereoselective reduction of prochiral ketones by using an F420-dependent alcohol dehydrogenase (2021), ChemBioChem, 22, 156-159 .
    View publication on PubMed

Organism

EC Number Organism UniProt Comment Textmining
1.1.98.5 Methanoculleus thermophilus O93734
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Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.98.5 1-phenylpropan-1-one + reduced coenzyme F420 the (S)-alcohol is obtained in excellent enantiopurity (above 99% ee) Methanoculleus thermophilus (S)-1-phenylpropan-1-ol + oxidized coenzyme F420
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 ?
1.1.98.5 4-methylpentan-2-one + reduced coenzyme F420 the (S)-alcohol is obtained in excellent enantiopurity (above 99% ee) Methanoculleus thermophilus (S)-4-methylpentan-2-ol + oxidized coenzyme F420
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 ?
1.1.98.5 acetophenone + reduced coenzyme F420 the (S)-alcohol is obtained in excellent enantiopurity (above 99% ee) Methanoculleus thermophilus (S)-1-phenylethanol + oxidized coenzyme F420
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 ?
1.1.98.5 methoxyacetone + reduced coenzyme F420 the (S)-alcohol is obtained in excellent enantiopurity (above 99% ee) Methanoculleus thermophilus (2S)-1-methoxypropan-2-ol + oxidized coenzyme F420
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 ?
1.1.98.5 octan-3-one + reduced coenzyme F420 the (S)-alcohol is obtained in excellent enantiopurity (above 99% ee) Methanoculleus thermophilus (S)-3-octanol + oxidized coenzyme F420
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 ?
1.1.98.5 pentan-2-one + reduced coenzyme F420
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 Methanoculleus thermophilus (S)-2-pentanol + oxidized coenzyme F420
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 ?

Synonyms

EC Number Synonyms Comment Organism
1.1.98.5 ADF
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 Methanoculleus thermophilus
1.1.98.5 F420-dependent alcohol dehydrogenase
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 Methanoculleus thermophilus