EC Number   |
Activating Compound |
Reference |
|---|
   3.1.11.1 | 14-3-3 isoform eta |
- |
750362 |
| 3.1.11.1 | 14-3-3 isoform sigma |
- |
750362 |
| 3.1.11.1 | E. coli single-stranded binding protein |
four molecules bind to exonuclease, carboxy terminus is the recognition site for the exonuclease, binds ssDNA to establish a conformation suitable for replication, recombination and repair |
133942 |
| 3.1.11.1 | more |
ExoI enzymatic activity is stimulated by single-stranded DNA-binding protein, whereby the hydrophobic C-terminal residues play critical roles in ExoI binding |
707503 |
| 3.1.11.1 | more |
human BLM helicase, a member of the RecQ family, stimulates the nucleolytic activity of Exo1. Stimulation of hExo1 by BLM does not require ATP. Stimulation is specific because other RecQ homologs (human WRN, RecQ1, RecQ4 and RecQ5beta and Escherichia coli RecQ) fail to stimulate Exo1. RPA does not affect the nuclease activity of Exo1 alone, nor does it appreciably change substrate utilization by Exo1 in the presence of BLM helicase. BLM helicase physically interacts with Exo1 |
700958 |
| 3.1.11.1 | more |
human EXO1 excision depends on the presence of a G loop, requires a nick and depends on transcription and transcriptional orientation |
700957 |
| 3.1.11.1 | more |
ssDNA-binding protein stimulates ExoI by recruiting the enzyme. ExoI/ssDNA-binding protein complex formation is necessary, but not sufficient for ssDNA-binding protein stimulation of ExoI activity |
700988 |
| 3.1.11.1 | proliferating cell nuclear antigen |
- |
750362 |
