EC Number |
Natural Substrates |
---|
2.4.1.152 | GDP-beta-fucose + alpha2,3-sialyl N-acetyllactosaminyl-R |
FucT-VII and FucT-IV |
2.4.1.152 | GDP-beta-L-fucose + asialo-erythropoietin |
wild-type FUT9 efficiently fucosylates di-, tri- and tetraantennary N-glycans from asialoEPO |
2.4.1.152 | GDP-beta-L-fucose + beta-D-galactosyl-(1->4)-N-acetyl-D-glucosaminyl-R |
- |
2.4.1.152 | GDP-beta-L-fucose + N-acetyllactosamine |
- |
2.4.1.152 | GDP-beta-L-fucose + Neu5Acalpha-(2,3)-Galbeta-(1,4)-GlcNAcbeta-R |
the last step in sLex epitope formation is catalyzed byalpha(1,3)-fucosyltransferase VII, i.e. FucTVII, which transfers a fucosyl moiety from GDP-fucose to the core oligosaccharide structures, overview |
2.4.1.152 | GDP-beta-L-fucose + NeuAcalpha(2,3)-Galbeta(1,4)-GlcNAc-R |
sialyl-Lewisx terminal structure |
2.4.1.152 | GDP-beta-L-fucose + NeuAcalpha(2,3)-Galbeta(1,4)[SO3H-6]-GlcNAc-R |
sialyl-Lewisx terminal structure |
2.4.1.152 | more |
enzyme is involved in the expression of the sialyl-LewisX determinant, a ligand for E- and P-selectin |
2.4.1.152 | more |
the hepatocellular enzyme is involved in the synthesis of sialosyl LeX determinants on cirrhotic alpha1AGP |
2.4.1.152 | more |
the gene is capable of directing expression of the Lewis x Galbeta(1,4)(Fucalpha(1,3))GlcNAc, sialyl Lewis x NeuNAcalpha(2,3)Galbeta(1,4)(Fucalpha(1,3))GlcNAc, and difucosyl sialyl Lewis x NeuNAcalpha(2,3)Galbeta(1,4)(Fucalpha(1,3))GlcNAcbeta(1,3)Galbeta(1,4)(Fucalpha(1,3))GlcNAc epitopes |