EC Number |
Natural Substrates |
---|
3.2.1.31 | curcumin-beta-D-glucuronide + H2O |
curcumin, despite low systemic bioavailability, may be enzymatically activated (deconjugated) within GUSB-enriched bone to exert protective effects, a metabolic process that can also contribute to bone-protective effects of other highly glucuronidated dietary polyphenols |
3.2.1.31 | dermatan sulfate + H2O |
- |
3.2.1.31 | heparan sulfate + H2O |
- |
3.2.1.31 | luteolin triglucuronide + H2O |
- |
3.2.1.31 | more |
- |
3.2.1.31 | more |
role in physiology, in tissues, in body fluids |
3.2.1.31 | more |
activity is inducible by Met-Gly |
3.2.1.31 | more |
activity is not inducible by Met-Gly |
3.2.1.31 | more |
activity is slightly inducible by Met-Gly |
3.2.1.31 | more |
the potent beta-glucuronidase activity caused by the glucuronic acid conjugates from xenobiotics and endogenous compounds is a prime factor in the etiology of colon cancer |