EC Number   |
Posttranslational Modification |
Reference |
|---|
   2.3.1.48 | acetylation |
acetylation and autoacetylation regulates HBO1 activity. This regulation mainly occurs on Lys199 (K199) within the residues HLTGK (ac) HER in humans. In contrast, acetylation occurs at conserve site Lys277 in humans |
756418 |
| 2.3.1.48 | acetylation |
acetylation and autoacetylation regulates HBO1 activity. This regulation mainly occurs on Lys201. In contrast, acetylation occurs at another conserve site Lys279 in RNSGLSK(ac)EQ is downregulated in response to heat or X-ray treatments in mouse testis, indicating its functions in spermatogenesis |
756418 |
| 2.3.1.48 | acetylation |
hARD1/NAA10 undergoes autoacetylation at residue K136, which is critical to stimulate its lysine acetyltransferase (KAT) activity. Recombinant hARD1 has the tendency to lose its lysine acetylation activity in vitro. The autoacetylation is not required for NAT activity of ARD1/Naa10 |
757723 |
| 2.3.1.48 | acetylation |
hARD1/NAA10 undergoes autoacetylation, which is critical to stimulate its KAT activity. In vitro, the autoacetylation activity of purified hARD1 fails to last long. hARD1/NAA10 is known to acetylate its K136 lysine residue, and K136 acetylation is important to stimulate its KAT activity. The enzyme K136R and DN mutants fail to acetylate themselves |
757723 |
| 2.3.1.48 | acetylation |
MYST enzymes have their acetylase activity regulated by autoacetylation. Autoacetylation is an important process in modulating the activity of MYST family members |
756850 |
| 2.3.1.48 | more |
acetyltransferase activity requires active site lysine autoacetylation at a conserved lysine K262 |
719370 |
| 2.3.1.48 | more |
HBO1 can be either ubiquitinated or act as an ubiquitin ligase |
756418 |
| 2.3.1.48 | more |
p300 performs autoacetylation e.g. at Lys1555, Lys1554, Lys1552, and Lys1546, overview |
674735 |
| 2.3.1.48 | more |
the histone acetyltransferase KAT2A/GCN5 binds directly to the autophagosome protein MAP1LC3/LC3 (microtubule associated protein 1 light chain) via a conserved LC3-interacting region (LIR) domain. This interaction is required for KAT2A sequestration in autophagosomes and degradation by lysosomal acid hydrolases. Suppression of autophagy results in KAT2A accumulation. The LIR domain of KAT2A is required for KAT2A degradation |
755921 |
| 2.3.1.48 | more |
YfmK does not acetylate itself |
-, 758249 |
