EC Number   |
General Information |
Reference  |
|---|
   3.1.1.32 | physiological function |
simultaneous purification of plasmalogens and sphingomyelin with PLA1 in human erythrocytes. Relative concentration of the plasmalogens after treatment with PLA1 is 92% of phospholipids in the supernatant fraction, and that of sphingomyelin is 97.7% in the precipitate fraction |
707787 |
| 3.1.1.32 | physiological function |
is capable for activation of human basophils, relevance of Ves v 1 in hymenoptera venom allergy |
708202 |
| 3.1.1.32 | malfunction |
knockdown of intracellular PLA1gamma expression by RNAi does not affect the anterograde transport of ts045 vesicular stomatitis virus protein (VSVGts045) but dramatically delays two types of Golgi-to-endoplasmic reticulum retrograde membrane transport, i.e., transfer of the Golgi membrane into the endoplasmic reticulum in the presence of brefeldin A and delivery of cholera toxin B subunit from the Golgi complex to the endoplasmic reticulum. Knockdown of intracellular PLA1gamma does not impair coat protein complex I- and Rab6-dependent retrograde transports represented by ERGIC-53 recycling and endoplasmic reticulum delivery of Shiga toxin, respectively |
709054 |
| 3.1.1.32 | physiological function |
mediates a specific retrograde membrane transport pathway between the endoplasmic reticulum and the Golgi complex |
709054 |
| 3.1.1.32 | physiological function |
H-Rev107 functions principally as a Ca2+-independent PLA1/2 with a higher PLA1 activity. Transient expression of H-Rev107 in COS-7 cells does not appear to influence cell proliferation |
709425 |
| 3.1.1.32 | evolution |
mechanisms of activation of the ExoU family of PLAs may be evolutionarily conserved |
715386 |
| 3.1.1.32 | physiological function |
the phospholipase A1 activity of lysophospholipase A-I links platelet activation to LPA production during blood coagulation |
715840 |
| 3.1.1.32 | malfunction |
Because orientation of seam cell division is randomized relative to the A-P axis in ipla-1 mutants, ipla-1 mutants exhibit aberrant orientation of seam cell divisions. Acl-8 acl-9 acl-10 triple mutations also cause misorientation of seam cell divisions similar to that observed in ipla-1 mutants |
716165 |
| 3.1.1.32 | metabolism |
intracellular phospholipase A1 and acyltransferase are involved in Caenorhabditis elegans stem cell divisions |
716165 |
| 3.1.1.32 | physiological function |
intracellular phospholipase A1 and acyltransferase, which are involved in Caenorhabditis elegans stem cell divisions, determine the sn-1 fatty acyl chain of phosphatidylinositol |
716165 |
