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EC Number	General Information	Commentary	Reference
1.3.1.22	more	mutations of the SRD5A2 gene, e.g. Leu55Gln, cause 5alpha-reductase type 2 deficiency and masculinization defects of varying degree as a result of a prenatal lack of 5alpha-dihydrotestosterone to predominantly female phenotype newborn patient, detailed overview	712125
1.3.1.22	physiological function	conversion of testosterone to 5alpha-dihydrotestosterone is essential for correct development of genetalia, overview	712125
1.3.1.22	physiological function	SRD5A2 and dihydrotestosterone play important roles in benign prostatic hyperplasia	713595

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Release 2023.1 (January 2023)