EC Number |
General Information |
Reference |
---|
2.3.1.165 | metabolism |
in toxigenic Penicillium expansum strains msas is involved in the biosynthesis of the mycotoxin patulin which is toxic for animals and plants |
703577 |
2.3.1.165 | metabolism |
production of 6-methylsalicylic acid as the first step in biosythesis of isoasperlactone and asperlactone |
703824 |
2.3.1.165 | evolution |
6-methylsalicylic acid synthase belongs to the iterative type I polyketide synthases |
719864 |
2.3.1.165 | physiological function |
6-methylsalicylic acid synthase from Aspergillus terreus is not involved in dehydration of the beta-hydroxytriketide intermediate tethered on the acyl carrier protein but catalyzes thioester hydrolysis to release the product from the acyl carrier protein, via its thioester hydrolase domain, a product-releasing domain that is located in the middle of a multidomain iterative type I polyketide synthase, ATX by itself can synthesize tetraketide and release 6-methylsalicylate as the free acid without involvement of serine protease-type thioesterase, product-releasing mechanism, overview |
719864 |
2.3.1.165 | physiological function |
enzyme is involved in synthesis of yanuthones D and E |
-, 735929 |
2.3.1.165 | physiological function |
in Aspergillus aculeatus, 6-methylsalicylic acid is incorporated into aculinic acid, which further incorporates into three compounds named aculins A and B, and epi-aculin A |
735950 |