EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
1.1.98.4 | menaquinone + reduced coenzyme F420 |
the FqoF protein forms the input device of the protein complex which oxidizes coenzyme F420H2. Thus, this polypeptide replaces the NADH-oxidizing module of NADH dehydrogenases of bacteria which are not found in Archaeoglobus fulgidus. Then the electrons are channeled to the membrane-associated fragment composed of FqoBCDI, which is homologous to the corresponding module of complex I. As the subunits FqoAHJKLMN are highly hydrophobic and are related to polypeptides comprising the membrane fragment of complex I, they may form the membrane-integral module of the F420H2:quinone oxidoreductase that is responsible for the reduction of a special menaquinone found in the cytoplasmic membrane of Archaeoglobus fulgidus |
Archaeoglobus fulgidus |
menaquinol + oxidized coenzyme F420 |
- |
? |
1.1.98.4 | menaquinone + reduced coenzyme F420 |
the physiological electron acceptor of the enzyme complex is most likely the menaquinone found in the membrane fraction of Archaeoglobus fulgidus. The reduction of menaquinone by F420H2 in Archaeoglobus fulgidus is catalyzed by a membrane-bound complex composed of at least seven different subunits. It contains 1-2 mol FAD and8 mol Fe-S/mol complex. The complex subunit composition indicates that the F420H2:quinone oxidoreductase complex from Archaeoglobus fulgidus is functionally analogous to the NADH:quinone oxidoreductase complex from mitochondria and bacteria |
Archaeoglobus fulgidus |
menaquinol + oxidized coenzyme F420 |
- |
? |
1.1.98.4 | more |
the enzyme is involved in the reduction of heterodisulfide |
Methanosarcina mazei Gö1 |
? |
- |
? |
1.1.98.4 | more |
no activity with NADH and NADPH |
Archaeoglobus fulgidus |
? |
- |
? |
1.1.98.4 | more |
no hydrogenase activity. No activity with NAD+ or NADP+ |
Methanosarcina mazei Gö1 |
? |
- |
? |
1.1.98.4 | more |
the enzyme is involved in the reduction of heterodisulfide |
Methanosarcina mazei Gö1 DSM 3647 |
? |
- |
? |
1.1.98.4 | more |
no hydrogenase activity. No activity with NAD+ or NADP+ |
Methanosarcina mazei Gö1 DSM 3647 |
? |
- |
? |
1.1.98.4 | oxidized methyl viologen + reduced coenzyme F420 |
the purified subunit oxidizes reduced cofactor F420 using the electron-acceptor system methyl viologen plus metronidazole |
Archaeoglobus fulgidus |
reduced methyl viologen + oxidized coenzyme F420 |
- |
? |
1.1.98.4 | tetramethyl-4-benzoquinone + reduced coenzyme F420 |
i.e. menadione |
Methanosarcina mazei Gö1 |
tetramethyl-1,4-benzoquinol + oxidized coenzyme F420 |
- |
? |
1.1.98.4 | tetramethyl-4-benzoquinone + reduced coenzyme F420 |
i.e. menadione |
Methanosarcina mazei Gö1 DSM 3647 |
tetramethyl-1,4-benzoquinol + oxidized coenzyme F420 |
- |
? |