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EC Number
Substrates
Commentary Substrates
Organism
Products
Commentary (Products)
Reversibility
1.2.1.95
(S)-2-amino-6-oxohexanoate + NADP+ + AMP + diphosphate
presence of ATP and Mg2+ required
Candida albicans
L-2-aminoadipate + NADPH + H+ + ATP
-
?
1.2.1.95
adipate + NADPH + H+ + ATP
-
Saccharomyces cerevisiae
adipate semialdehyde + NADP+ + AMP + diphosphate
-
?
1.2.1.95
D-2-aminoadipate + NADPH + H+ + ATP
-
Saccharomyces cerevisiae
(R)-2-amino-6-oxohexanoate + NADP+ + AMP + diphosphate
-
?
1.2.1.95
L-2-aminoadipate + NADPH + H+ + ATP
-
Penicillium chrysogenum
(S)-2-amino-6-oxohexanoate + NADP+ + AMP + diphosphate
-
?
1.2.1.95
L-2-aminoadipate + NADPH + H+ + ATP
-
Saccharomyces cerevisiae
(S)-2-amino-6-oxohexanoate + NADP+ + AMP + diphosphate
-
?
1.2.1.95
L-2-aminoadipate + NADPH + H+ + ATP
-
Acremonium chrysogenum
(S)-2-amino-6-oxohexanoate + NADP+ + AMP + diphosphate
-
?
1.2.1.95
L-2-aminoadipate + NADPH + H+ + ATP
-
Gelatoporia subvermispora
(S)-2-amino-6-oxohexanoate + NADP+ + AMP + diphosphate
-
?
1.2.1.95
L-2-aminoadipate + NADPH + H+ + ATP
-
Acremonium chrysogenum ATCC 48272
(S)-2-amino-6-oxohexanoate + NADP+ + AMP + diphosphate
-
?
1.2.1.95
more
in strains Q176, D6/1014/A, and P2, the enzyme exhibits decreasing affinity for alpha-aminoadipate with increasing capacity of the respective strain to produce penicillin
Penicillium chrysogenum
?
-
?
1.2.1.95
more
no substrates: adipic acid, DL-diaminopimelic acid, L-glutamate
Penicillium chrysogenum
?
-
?
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