EC Number   |
Substrates |
Organism |
Products |
Reversibility |
|---|
   4.2.1.141 | 2-dehydro-3-deoxy-D-arabinonate |
- |
Saccharolobus solfataricus |
2,5-dioxopentanoate + H2O |
- |
? |
| 4.2.1.141 | 2-dehydro-3-deoxy-D-arabinonate |
- |
Sulfolobus acidocaldarius |
2,5-dioxopentanoate + H2O |
- |
? |
| 4.2.1.141 | 2-dehydro-3-deoxy-D-arabinonate |
key enzyme in degradation of D-arabinose |
Saccharolobus solfataricus |
2,5-dioxopentanoate + H2O |
- |
? |
| 4.2.1.141 | 2-dehydro-3-deoxy-D-arabinonate |
the enzyme is involved in the conversion of D-arabinose into the tricarboxylic acid cycle intermediate 2-oxoglutarate via the pentose oxidation pathway |
Saccharolobus solfataricus |
2,5-dioxopentanoate + H2O |
- |
? |
| 4.2.1.141 | 2-dehydro-3-deoxy-D-arabinonate |
the catalytic activity of the protein is investigated by performing indirect enzyme assays using arabinonate dehydratase with D-arabinonate as a substrate. A 50% decrease in the yield of 2-dehydro-3-deoxy-D-arabinonate is observed when both enzymes are co-incubated in the presence of Mg2+. Given the fact that D-arabinonate is converted to 2-oxoglutarate in D-arabinose cell-free extract, this enzyme is anticipated to be responsible for the dehydration of 2-dehydro-3-deoxy-D-arabinonate to the aldehyde 2,5-dioxopentanoate. Due to the unavailability of 2-dehydro-3-deoxy-D-arabinonate, it is not possible to show this in a direct enzyme assay. 2-Oxoglutarate is produced in an indirect assay using arabinonate dehydratase, the putative 2-dehydro-3-deoxy-D-arabinonate dehydratase and the predicted aldehyde dehydrogenase |
Saccharolobus solfataricus |
2,5-dioxopentanoate + H2O |
- |
? |
| 4.2.1.141 | 2-dehydro-3-deoxy-D-arabinonate |
- |
Sulfolobus acidocaldarius ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770 |
2,5-dioxopentanoate + H2O |
- |
? |
| 4.2.1.141 | 2-dehydro-3-deoxy-D-arabinonate |
- |
Saccharolobus solfataricus P2 |
2,5-dioxopentanoate + H2O |
- |
? |
| 4.2.1.141 | 2-dehydro-3-deoxy-D-arabinonate |
key enzyme in degradation of D-arabinose |
Saccharolobus solfataricus P2 |
2,5-dioxopentanoate + H2O |
- |
? |
| 4.2.1.141 | 2-dehydro-3-deoxy-D-arabinonate |
the enzyme is involved in the conversion of D-arabinose into the tricarboxylic acid cycle intermediate 2-oxoglutarate via the pentose oxidation pathway |
Saccharolobus solfataricus P2 |
2,5-dioxopentanoate + H2O |
- |
? |
| 4.2.1.141 | 2-dehydro-3-deoxy-D-arabinonate |
the catalytic activity of the protein is investigated by performing indirect enzyme assays using arabinonate dehydratase with D-arabinonate as a substrate. A 50% decrease in the yield of 2-dehydro-3-deoxy-D-arabinonate is observed when both enzymes are co-incubated in the presence of Mg2+. Given the fact that D-arabinonate is converted to 2-oxoglutarate in D-arabinose cell-free extract, this enzyme is anticipated to be responsible for the dehydration of 2-dehydro-3-deoxy-D-arabinonate to the aldehyde 2,5-dioxopentanoate. Due to the unavailability of 2-dehydro-3-deoxy-D-arabinonate, it is not possible to show this in a direct enzyme assay. 2-Oxoglutarate is produced in an indirect assay using arabinonate dehydratase, the putative 2-dehydro-3-deoxy-D-arabinonate dehydratase and the predicted aldehyde dehydrogenase |
Saccharolobus solfataricus P2 |
2,5-dioxopentanoate + H2O |
- |
? |
