EC Number |
Cofactor |
Reference |
---|
1.1.1.22 | 3-acetylpyridine adenine dinucleotide |
can replace NAD+ |
286293, 286297, 286300 |
1.1.1.22 | beta-NAD+ |
- |
286296 |
1.1.1.22 | more |
no activity with NADP+ |
741372 |
1.1.1.22 | more |
no constantly bound chromophoric cofactors, i.e. NAD+, required |
286301 |
1.1.1.22 | NAD+ |
- |
654351, 655477, 656220, 656240, 657082, 657189, 666609, 667513, 667848, 669522, 684611, 687474, 710750, 710762, 710889, 711665, 721871, 725478, 725729, 739891, 739967, 739981, 740128, 740710, 740715, 740935, 760612 |
1.1.1.22 | NAD+ |
activity with NADP+ is about 20% of that with NAD+ |
688084 |
1.1.1.22 | NAD+ |
cofactor binding triggers the formation of the 32 symmetry enzyme hexamer, which is the catalytically relevant state |
724364 |
1.1.1.22 | NAD+ |
specific for |
286294, 741372 |
1.1.1.22 | NADH |
- |
666609, 684611, 687474 |
1.1.1.22 | NADP+ |
about 5-12% of the activity with NAD+ |
725729 |