EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category  |
Confidence Level |
|---|
   1.14.14.73 | Breast Neoplasms |
27720933 |
Activation of the pro-migratory bone morphogenetic protein receptor 1B gene in human MDA-MB-468 triple-negative breast cancer cells that over-express CYP2J2. |
causal interaction
ongoing research
therapeutic application
unassigned |
4
3
1
0 |
| 1.14.14.73 | Carcinoma |
29655687 |
The inhibitory potential of Broussochalcone A for the human cytochrome P450 2J2 isoform and its anti-cancer effects via FOXO3 activation. |
causal interaction
ongoing research
unassigned |
1
3
0 |
| 1.14.14.73 | Colitis, Ulcerative |
29580941 |
Increased epoxyeicosatrienoic acids may be part of a protective mechanism in human ulcerative colitis, with increased CYP2J2 and reduced soluble epoxide hydrolase expression. |
causal interaction
diagnostic usage
ongoing research
unassigned |
3
1
3
0 |
| 1.14.14.73 | Colitis, Ulcerative |
31249444 |
Role of cytochrome P450 polymorphisms and functions in development of ulcerative colitis. |
causal interaction
ongoing research
unassigned |
3
3
0 |
| 1.14.14.73 | Coronary Disease |
17429317 |
CYP2J2 and CYP2C8 polymorphisms and coronary heart disease risk: the Atherosclerosis Risk in Communities (ARIC) study. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
3
2
1 |
| 1.14.14.73 | Heart Failure |
32210298 |
CYP2J2 Modulates Diverse Transcriptional Programs in Adult Human Cardiomyocytes. |
causal interaction
unassigned |
4
0 |
| 1.14.14.73 | Hypertension |
23647230 |
Structural basis for the mutation-induced dysfunction of human CYP2J2: a computational study. |
causal interaction
unassigned |
3
0 |
| 1.14.14.73 | Neoplasms |
16495056 |
Design and synthesis of selective, high-affinity inhibitors of human cytochrome P450 2J2. |
causal interaction
therapeutic application
unassigned |
4
3
0 |
| 1.14.14.73 | Neoplasms |
17908963 |
Comparative Analysis of Peritoneum and Tumor Eicosanoids and Pathways in Advanced Ovarian Cancer. |
causal interaction
unassigned |
1
0 |
| 1.14.14.73 | Neoplasms |
21477627 |
The roles of CYP450 epoxygenases and metabolites, epoxyeicosatrienoic acids, in cardiovascular and malignant diseases. |
causal interaction
therapeutic application
unassigned |
3
4
0 |
