EC Number |
Protein Variants |
Reference |
---|
1.13.11.47 | C69S/H251A |
inactive mutant |
713426 |
1.13.11.47 | D120A |
site-directed mutagenesism the mutant shows altered kinetics and reduced catalytic efficiency compared to the wild-type enzyme |
-, 713426 |
1.13.11.47 | D126A |
mutation in the active site His-251/Asp-126 dyad, 9fold decrease in kcat/Km |
742869 |
1.13.11.47 | D126A |
site-directed mutagenesis, the mutant shows altered kinetics and reduced catalytic efficiency compared to the wild-type enzyme |
-, 713426 |
1.13.11.47 | H102L |
site-directed mutagenesis, the mutant shows altered kinetics and reduced catalytic efficiency compared to the wild-type enzyme |
-, 713426 |
1.13.11.47 | H251A |
mutation in the active site His-251/Asp-126 dyad, 5500fold decrease in kcat/Km |
742869 |
1.13.11.47 | H251A |
site-directed mutagenesis, the mutant shows altered kinetics and reduced catalytic efficiency compared to the wild-type enzyme |
-, 713426 |
1.13.11.47 | H38A |
site-directed mutagenesis, the mutant shows altered kinetics and reduced catalytic efficiency compared to the wild-type enzyme |
-, 713426 |
1.13.11.47 | S101A |
site-directed mutagenesis, the mutant shows altered kinetics and reduced catalytic efficiency compared to the wild-type enzyme |
-, 713426 |