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EC Number
Protein Variants
Commentary
Reference
3.4.22.28
A133S
processed enzyme, polydispersity of 35%
667051
3.4.22.28
A133S/C142S
processed enzyme, polydispersity of 29%
667051
3.4.22.28
C142A
active mutant
732414
3.4.22.28
C142A
mutant shows reduced activity
-
,
681679
3.4.22.28
C142L
active mutant
732414
3.4.22.28
C142L
introduction of the C142L mutation into a type O1K FMDV has no significant effect on the infectivity of the virus in tissue culture
709535
3.4.22.28
C142L
mutant shows increased activity
-
,
681679
3.4.22.28
C142S
active mutant
732414
3.4.22.28
C142S
enhanced solubility
-
,
669311
3.4.22.28
C142S
mutation has no effect onsubstrate specificity but drastically reduces the proteolytic activity of the enzyme to less than 1% of the wild type activity
-
,
681679
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