Sequence of NSAR_AMYSP
EC Number:4.2.1.113
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
(1R,6R)-6-hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate = 2-succinylbenzoate + H2O
Other sequences found for EC No. 4.2.1.113
General information:
Sequence
0 MKLSGVELRR VQMPLVAPFR TSFGTQSVRE LLLLRAVTPA GEGWGECVTM AGPLYSSEYN
60 DGAEHVLRHY LIPALLAAED ITAAKVTPLL AKFKGHRMAK GALEMAVLDA ELRAHERSFA
120 AELGSVRDSV PCGVSVGIMD TIPQLLDVVG GYLDEGYVRI KLKIEPGWDV EPVRAVRERF
180 GDDVLLQVDA NTAYTLGDAP QLARLDPFGL LLIEQPLEEE DVLGHAELAR RIQTPICLDE
240 SIVSARAAAD AIKLGAVQIV NIKPGRVGGY LEARRVHDVC AAHGIPVWCG GMIETGLGRA
300 ANVALASLPN FTLPGDTSAS DRFYKTDITE PFVLSGGHLP VPTGPGLGVA PIPELLDEVT
360 TAKVWIGS
Download this sequence
in fasta formatDownload all sequences for 4.2.1.113
in fasta format
in csv (Excel, OpenOffice) formatSequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
197000
Tokuyama S.,Hatano K.
Cloning, DNA sequencing and heterologous expression of the gene for thermostable N-acylamino acid racemase from Amycolatopsis sp. TS-1-60 in Escherichia coli.
Appl. Microbiol. Biotechnol.
42
884-889
1995
197001
Tokuyama S.,Hatano K.
Purification and properties of thermostable N-acylamino acid racemase from Amycolatopsis sp. TS-1-60.
Appl. Microbiol. Biotechnol.
42
853-859
1995
197002
Palmer D.R.,Garrett J.B.,Sharma V.,Meganathan R.,Babbitt P.C.,Gerlt J.A.
Unexpected divergence of enzyme function and sequence: 'N-acylamino acid racemase' is o-succinylbenzoate synthase.
Biochemistry
38
4252-4258
1999
197003
Taylor Ringia E.A.,Garrett J.B.,Thoden J.B.,Holden H.M.,Rayment I.,Gerlt J.A.
Evolution of enzymatic activity in the enolase superfamily: functional studies of the promiscuous o-succinylbenzoate synthase from Amycolatopsis.
Biochemistry
43
224-229
2004
197004
Glasner M.E.,Fayazmanesh N.,Chiang R.A.,Sakai A.,Jacobson M.P.,Gerlt J.A.,Babbitt P.C.
Evolution of structure and function in the o-succinylbenzoate synthase/N-acylamino acid racemase family of the enolase superfamily.
J. Mol. Biol.
360
228-250
2006
197005
McMillan A.W.,Lopez M.S.,Zhu M.,Morse B.C.,Yeo I.C.,Amos J.,Hull K.,Romo D.,Glasner M.E.
Role of an active site loop in the promiscuous activities of Amycolatopsis sp. T-1-60 NSAR/OSBS.
Biochemistry
53
4434-4444
2014
197006
Thoden J.B.,Taylor Ringia E.A.,Garrett J.B.,Gerlt J.A.,Holden H.M.,Rayment I.
Evolution of enzymatic activity in the enolase superfamily: structural studies of the promiscuous o-succinylbenzoate synthase from Amycolatopsis.
Biochemistry
43
5716-5727
2004
197007
Baxter S.,Royer S.,Grogan G.,Brown F.,Holt-Tiffin K.E.,Taylor I.N.,Fotheringham I.G.,Campopiano D.J.
An improved racemase/acylase biotransformation for the preparation of enantiomerically pure amino acids.
J. Am. Chem. Soc.
134
19310-19313
2012
