Sequence of DHOM_CORGL
EC Number:1.1.1.3
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
homoserine dehydrogenase
P08499
Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025)
445
46438
Reaction
L-homoserine + NAD(P)+ = L-aspartate 4-semialdehyde + NAD(P)H + H+
Other sequences found for EC No. 1.1.1.3
General information:
Sequence
0 MTSASAPSFN PGKGPGSAVG IALLGFGTVG TEVMRLMTEY GDELAHRIGG PLEVRGIAVS
60 DISKPREGVA PELLTEDAFA LIEREDVDIV VEVIGGIEYP REVVLAALKA GKSVVTANKA
120 LVAAHSAELA DAAEAANVDL YFEAAVAGAI PVVGPLRRSL AGDQIQSVMG IVNGTTNFIL
180 DAMDSTGADY ADSLAEATRL GYAEADPTAD VEGHDAASKA AILASIAFHT RVTADDVYCE
240 GISNISAADI EAAQQAGHTI KLLAICEKFT NKEGKSAISA RVHPTLLPVS HPLASVNKSF
300 NAIFVEAEAA GRLMFYGNGA GGAPTASAVL GDVVGAARNK VHGGRAPGES TYANLPIADF
360 GETTTRYHLD MDVEDRVGVL AELASLFSEQ GISLRTIRQE ERDDDARLIV VTHSALESDL
420 SRTVELLKAK PVVKAINSVI RLERD
Download this sequence
in fasta formatDownload all sequences for 1.1.1.3
in fasta format
in csv (Excel, OpenOffice) formatSequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
25363
Peoples O.P.,Liebl W.,Bodis M.,Maeng P.J.,Follettie M.T.,Archer J.A.C.,Sinskey A.J.
Nucleotide sequence and fine structural analysis of the Corynebacterium glutamicum hom-thrB operon.
Mol. Microbiol.
2
63-72
1988
25364
Mateos L.M.,del Real G.,Aguilar A.,Martin J.F.
Nucleotide sequence of the homoserine dehydrogenase (thr A) gene of Brevibacterium lactofermentum.
Nucleic Acids Res.
15
10598-10598
1987
25365
Sugimoto M.,Tanaka A.,Suzuki T.,Matsui H.,Nakamori S.,Takagi H.
Sequence analysis of functional regions of homoserine dehydrogenase genes from L-lysine and L-threonine-producing mutants of Brevibacterium lactofermentum.
Biosci. Biotechnol. Biochem.
61
1760-1762
1997
25366
Ikeda M.,Nakagawa S.
The Corynebacterium glutamicum genome: features and impacts on biotechnological processes.
Appl. Microbiol. Biotechnol.
62
99-109
2003
25367
Kalinowski J.,Bathe B.,Bartels D.,Bischoff N.,Bott M.,Burkovski A.,Dusch N.,Eggeling L.,Eikmanns B.J.,Gaigalat L.,Goesmann A.,Hartmann M.,Huthmacher K.,Kraemer R.,Linke B.,McHardy A.C.,Meyer F.,Moeckel B.,Pfefferle W.,Puehler A.,Rey D.A.,Rueckert C.,Rupp O.,Sahm H.,Wendisch V.F.,Wiegraebe I.,Tauch A.
The complete Corynebacterium glutamicum ATCC 13032 genome sequence and its impact on the production of L-aspartate-derived amino acids and vitamins.
J. Biotechnol.
104
5-25
2003
25368
Miyajima R.,Shiio I.
Regulation of aspartate family amino acid biosynthesis in Brevibacterium flavum. 3. Properties of homoserine dehydrogenase.
J. Biochem.
68
311-319
1970
25369
Archer J.A.,Solow-Cordero D.E.,Sinskey A.J.
A C-terminal deletion in Corynebacterium glutamicum homoserine dehydrogenase abolishes allosteric inhibition by L-threonine.
Gene
107
53-59
1991
25370
Reinscheid D.J.,Eikmanns B.J.,Sahm H.
Analysis of a Corynebacterium glutamicum hom gene coding for a feedback-resistant homoserine dehydrogenase.
J. Bacteriol.
173
3228-3230
1991
