Sequence of LPIN1_MOUSE

phosphatidate phosphatase

Q91ZP3

924

102002

438274

Huffman T.A.,Mothe-Satney I.,Lawrence J.C. Jr.

Insulin-stimulated phosphorylation of lipin mediated by the mammalian target of rapamycin.

Proc. Natl. Acad. Sci. U.S.A.

99

1047-1052

2002

438275

Peterfy M.,Phan J.,Xu P.,Reue K.

Lipodystrophy in the fld mouse results from mutation of a new gene encoding a nuclear protein, lipin.

Nat. Genet.

27

121-124

2001

438276

Carninci P.,Kasukawa T.,Katayama S.,Gough J.,Frith M.C.,Maeda N.,Oyama R.,Ravasi T.,Lenhard B.,Wells C.,Kodzius R.,Shimokawa K.,Bajic V.B.,Brenner S.E.,Batalov S.,Forrest A.R.,Zavolan M.,Davis M.J.,Wilming L.G.,Aidinis V.,Allen J.E.,Ambesi-Impiombato A.,Apweiler R.,Aturaliya R.N.,Bailey T.L.,Bansal M.,Baxter L.,Beisel K.W.,Bersano T.,Bono H.,Chalk A.M.,Chiu K.P.,Choudhary V.,Christoffels A.,Clutterbuck D.R.,Crowe M.L.,Dalla E.,Dalrymple B.P.,de Bono B.,Della Gatta G.,di Bernardo D.,Down T.,Engstrom P.,Fagiolini M.,Faulkner G.,Fletcher C.F.,Fukushima T.,Furuno M.,Futaki S.,Gariboldi M.,Georgii-Hemming P.,Gingeras T.R.,Gojobori T.,Green R.E.,Gustincich S.,Harbers M.,Hayashi Y.,Hensch T.K.,Hirokawa N.,Hill D.,Huminiecki L.,Iacono M.,Ikeo K.,Iwama A.,Ishikawa T.,Jakt M.,Kanapin A.,Katoh M.,Kawasawa Y.,Kelso J.,Kitamura H.,Kitano H.,Kollias G.,Krishnan S.P.,Kruger A.,Kummerfeld S.K.,Kurochkin I.V.,Lareau L.F.,Lazarevic D.,Lipovich L.,Liu J.,Liuni S.,McWilliam S.,Madan Babu M.,Madera M.,Marchionni L.,Matsuda H.,Matsuzawa S.,Miki H.,Mignone F.,Miyake S.,Morris K.,Mottagui-Tabar S.,Mulder N.,Nakano N.,Nakauchi H.,Ng P.,Nilsson R.,Nishiguchi S.,Nishikawa S.,Nori F.,Ohara O.,Okazaki Y.,Orlando V.,Pang K.C.,Pavan W.J.,Pavesi G.,Pesole G.,Petrovsky N.,Piazza S.,Reed J.,Reid J.F.,Ring B.Z.,Ringwald M.,Rost B.,Ruan Y.,Salzberg S.L.,Sandelin A.,Schneider C.,Schoenbach C.,Sekiguchi K.,Semple C.A.,Seno S.,Sessa L.,Sheng Y.,Shibata Y.,Shimada H.,Shimada K.,Silva D.,Sinclair B.,Sperling S.,Stupka E.,Sugiura K.,Sultana R.,Takenaka Y.,Taki K.,Tammoja K.,Tan S.L.,Tang S.,Taylor M.S.,Tegner J.,Teichmann S.A.,Ueda H.R.,van Nimwegen E.,Verardo R.,Wei C.L.,Yagi K.,Yamanishi H.,Zabarovsky E.,Zhu S.,Zimmer A.,Hide W.,Bult C.,Grimmond S.M.,Teasdale R.D.,Liu E.T.,Brusic V.,Quackenbush J.,Wahlestedt C.,Mattick J.S.,Hume D.A.,Kai C.,Sasaki D.,Tomaru Y.,Fukuda S.,Kanamori-Katayama M.,Suzuki M.,Aoki J.,Arakawa T.,Iida J.,Imamura K.,Itoh M.,Kato T.,Kawaji H.,Kawagashira N.,Kawashima T.,Kojima M.,Kondo S.,Konno H.,Nakano K.,Ninomiya N.,Nishio T.,Okada M.,Plessy C.,Shibata K.,Shiraki T.,Suzuki S.,Tagami M.,Waki K.,Watahiki A.,Okamura-Oho Y.,Suzuki H.,Kawai J.,Hayashizaki Y.

The transcriptional landscape of the mammalian genome.

Science

309

1559-1563

2005

438277

Peterfy M.,Phan J.,Reue K.

Alternatively spliced lipin isoforms exhibit distinct expression pattern, subcellular localization, and role in adipogenesis.

J. Biol. Chem.

280

32883-32889

2005

438278

Finck B.N.,Gropler M.C.,Chen Z.,Leone T.C.,Croce M.A.,Harris T.E.,Lawrence J.C. Jr.,Kelly D.P.

Lipin 1 is an inducible amplifier of the hepatic PGC-1alpha/PPARalpha regulatory pathway.

Cell Metab.

4

199-210

2006

438279

Harris T.E.,Huffman T.A.,Chi A.,Shabanowitz J.,Hunt D.F.,Kumar A.,Lawrence J.C. Jr.

Insulin controls subcellular localization and multisite phosphorylation of the phosphatidic acid phosphatase, lipin 1.

J. Biol. Chem.

282

277-286

2007

438280

Donkor J.,Sariahmetoglu M.,Dewald J.,Brindley D.N.,Reue K.

Three mammalian lipins act as phosphatidate phosphatases with distinct tissue expression patterns.

J. Biol. Chem.

282

3450-3457

2007

438281

Donkor J.,Zhang P.,Wong S.,O'Loughlin L.,Dewald J.,Kok B.P.,Brindley D.N.,Reue K.

A conserved serine residue is required for the phosphatidate phosphatase activity but not the transcriptional coactivator functions of lipin-1 and lipin-2.

J. Biol. Chem.

284

29968-29978

2009

438282

Liu G.H.,Gerace L.

Sumoylation regulates nuclear localization of lipin-1alpha in neuronal cells.

PLoS ONE

4

0-0

2009

438283

Huttlin E.L.,Jedrychowski M.P.,Elias J.E.,Goswami T.,Rad R.,Beausoleil S.A.,Villen J.,Haas W.,Sowa M.E.,Gygi S.P.

A tissue-specific atlas of mouse protein phosphorylation and expression.

Cell

143

1174-1189

2010

438284

Huang H.,Gao Q.,Peng X.,Choi S.Y.,Sarma K.,Ren H.,Morris A.J.,Frohman M.A.

piRNA-associated germline nuage formation and spermatogenesis require MitoPLD profusogenic mitochondrial-surface lipid signaling.

Dev. Cell

20

376-387

2011

438285

Han S.,Bahmanyar S.,Zhang P.,Grishin N.,Oegema K.,Crooke R.,Graham M.,Reue K.,Dixon J.E.,Goodman J.M.

Nuclear envelope phosphatase-regulatory subunit 1 (formerly TMEM188) is the metazoan SPO7 ortholog and functions in the lipin activation pathway.

J. Biol. Chem.

287

3123-3137

2012