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1.17.1.3: leucoanthocyanidin reductase

This is an abbreviated version!
For detailed information about leucoanthocyanidin reductase, go to the full flat file.

Word Map on EC 1.17.1.3

Reaction

(2R,3S)-catechin
+
NADP+
 +
H2O
=
2,3-trans-3,4-cis-leucocyanidin
 +
NADPH
 +
H+

Synonyms

ANR, anthocyanidin reductase, BAN, CsLAR, FeLAR1, FeLAR2, FeLAR3, LAR, LAR1, lar2, LARa, LarB, LarC, leucoanthocyanidin 4-reductase, leucoanthocyanidin reductase, leucocyanidin reductase, MdLAR1, MdLAR2, More, MtLAR, PaLAR3, PtrLAR1, PtrLAR3, reductase, leucoanthocyanidin, TcLAR, Vv lar1, Vv lar2

ECTree

     1 Oxidoreductases
         1.17 Acting on CH or CH2 groups
             1.17.1 With NAD+ or NADP+ as acceptor
                1.17.1.3 leucoanthocyanidin reductase

Inhibitors

Inhibitors on EC 1.17.1.3 - leucoanthocyanidin reductase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
(+)-catechin
-
-
2,3-cis-flavan-3,4-diol
slight inhibition
2,3-cis-flavan-3-ol
product inhibition
2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxychromenium
48% inhibition at 0.006 mM
3,4-trans-leucocyanidin
50% inhibition at 0.12 mM
3,4-trans-leucopelargonidin
50% inhibition at 0.46 mM
afzelechin
50% inhibition at 0.014 mM
catechin
50% inhibition at 0.012 mM
cyanidin
-
substrate inhibition at high concentration
delphinidin
97% inhibition at 0.06 mM
dihydroquercetin
epi-gallocatechin
50% inhibition at 1.4 mM
eriodictyol
53% inhibition at 0.01 mM
gallocatechin
50% inhibition at 0.28 mM
Na+
-
above 200 mM
NADP+
50% inhibition at 0.5 mM; slight inhibition
pelargonidin
quercetin
additional information
-