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1.21.1.1: iodotyrosine deiodinase

This is an abbreviated version!
For detailed information about iodotyrosine deiodinase, go to the full flat file.

Word Map on EC 1.21.1.1

Reaction

3-iodo-L-tyrosine
+
NADP+
 +
Iodide
=
3,5-diiodo-L-tyrosine
 +
NADPH
 +
H+

Synonyms

DEHAL1, Dehal1 protein, DEHAL1B, EC 1.22.1.1, iodotyrosine dehalogenase 1, iodotyrosine deiodinase, IYD, lyd, NADH oxidase/flavin reductase, SUP-18, SUP-18 IYD, TDH

ECTree

     1 Oxidoreductases
         1.21 Catalysing the reaction X-H + Y-H = X-Y
             1.21.1 With NAD+ or NADP+ as acceptor
                1.21.1.1 iodotyrosine deiodinase

Inhibitors

Inhibitors on EC 1.21.1.1 - iodotyrosine deiodinase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
2',3,4',5,6'-pentachlorobiphenyl-4-ol
-
2',3,4',6'-tetrachlorobiphenyl-4-ol
-
2,2',5,5'-tetrachlorobiphenyl-4-ol
-
2,2'-dipyridyl
-
-
2,3,6-tribromo-4-(2,4-dibromophenoxy)phenol
-
2,3-dibromo-4-(2,4-dibromophenoxy)phenol
-
2,5-dibromo-4-(2,4-dibromophenoxy)phenol
-
3,5-diiodo-L-tyrosine
-
pronounced substrate inhibition above 5 microM
3-bromo-4-(2,4-dibromophenoxy)phenol
-
3-hydroxy-2,2',5,5'-tetrachlorobiphenyl
-
4'-hydroxy-2,2',4,5'-tetrabromodiphenyl ether
-
-
4'-hydroxy-2,2',4-tribromodiphenyl ether
-
-
4,4'-dihydroxy-3,3',5,5'-tetrachlorobiphenyl
-
4-hydroxy-2',3,4',5,6'-pentachlorobiphenyl
-
-
4-hydroxy-2,2',3,4',5-pentabromodiphenyl ether
-
-
4-hydroxy-2,3,3',4'-tetrabromodiphenyl ether
-
-
5-bromo-2-(2,4-dibromophenoxy)phenol
-
5-bromo-2-(4-bromophenoxy)phenol
-
benzbromarone
bithionol
-
bromoxynil
-
closantel
-
erythrosine B
N-ethylmaleimide
-
-
nitroxynil
-
o-phenanthroline
-
-
oxyclozanide
-
phloxine B
Rose bengal
tribromsalan
-
triclosan
additional information
-