2.1.1.254: erythromycin 3''-O-methyltransferase
This is an abbreviated version!
For detailed information about erythromycin 3''-O-methyltransferase, go to the full flat file.
Reaction
Synonyms
EryG
ECTree
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Systematic Name
Systematic Name on EC 2.1.1.254 - erythromycin 3''-O-methyltransferase
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S-adenosyl-L-methionine:erythromycin C 3''-O-methyltransferase
The enzyme methylates the 3 position of the mycarosyl moiety of erythromycin C, forming the most active form of the antibiotic, erythromycin A. It can also methylate the precursor erythromycin D, forming erythromycin B, which is then converted to erythromycin A by EC 1.14.13.154, erythromycin 12 hydroxylase.