2.1.1.28: phenylethanolamine N-methyltransferase
This is an abbreviated version!
For detailed information about phenylethanolamine N-methyltransferase, go to the full flat file.
Word Map on EC 2.1.1.28
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2.1.1.28
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catecholamine
-
medulla
-
hydroxylase
-
adrenergic
-
dopamine
-
chromaffin
-
beta-hydroxylase
-
glucocorticoid
-
sympathetic
-
rostrally
-
catecholaminergic
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noradrenergic
-
innervation
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ventrolateral
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hypothalamic
-
corticosterone
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catecholamine-synthesizing
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oblongata
-
dopamine-beta-hydroxylase
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pnmt-immunoreactive
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perikarya
-
tractus
-
adrenomedullary
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proenkephalin
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dorsomedial
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sympathoadrenal
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intermediolateral
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alpha2-adrenoceptor
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1,2,3,4-tetrahydroisoquinoline
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coeruleus
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phenylethanolamine-n-methyltransferase
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postrema
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pnmt-ir
-
medicine
-
bulbospinal
-
normetanephrine
-
solitarii
-
analysis
- 2.1.1.28
- catecholamine
- medulla
- hydroxylase
-
adrenergic
- dopamine
-
chromaffin
- beta-hydroxylase
- glucocorticoid
-
sympathetic
-
rostrally
-
catecholaminergic
-
noradrenergic
-
innervation
-
ventrolateral
- hypothalamic
- corticosterone
-
catecholamine-synthesizing
- oblongata
- dopamine-beta-hydroxylase
-
pnmt-immunoreactive
- perikarya
-
tractus
-
adrenomedullary
- proenkephalin
-
dorsomedial
-
sympathoadrenal
-
intermediolateral
-
alpha2-adrenoceptor
- 1,2,3,4-tetrahydroisoquinoline
-
coeruleus
-
phenylethanolamine-n-methyltransferase
-
postrema
-
pnmt-ir
- medicine
-
bulbospinal
- normetanephrine
-
solitarii
- analysis
Reaction
Synonyms
hPNMT, methyltransferase, noradrenaline N-, NMT, noradrenalin methyltransferase, noradrenalin N-methyltransferase, noradrenaline N-methyltransferase, norepinephrin N-methyltransferase, norepinephrine methyltransferase, norepinephrine N-methyltransferase, phenethanolamine methyltransferase, phenethanolamine N-methyltransferase, PNMT
ECTree
2.1.1.28 phenylethanolamine N-methyltransferaseAdvanced search results
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results (Turnover Number
Turnover Number on EC 2.1.1.28 - phenylethanolamine N-methyltransferase
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TURNOVER NUMBER [1/s] 
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
IMAGE
0.0048
cis-(1R,2S)-2-amino-1-tetralol
wild type enzyme, assay mixture consists of 25 microl of 0.5 M phosphate buffer (pH 8.0), 5 microl of [methyl-3H]S-adenosyl-L-methionine containing approximately 2.5 X 10 00000 dpm, varying amounts of phenylethanolamine and unlabeled S-adenosyl-L-methionine, 20 microl enzyme and water at 30°C.
0.02
octopamine
wild type enzyme, assay mixture consists of 25 microl of 0.5 M phosphate buffer (pH 8.0), 5 microl of [methyl-3H]S-adenosyl-L-methionine containing approximately 2.5 X 10 00000 dpm, varying amounts of phenylethanolamine and unlabeled S-adenosyl-L-methionine, 20 microl enzyme and water at 30°C.
0.00017
phenylethanolamine
mutant E185Q, assay mixture consists of 25 microl of 0.5 M phosphate buffer (pH 8.0), 5 microl of [methyl-3H]S-adenosyl-L-methionine containing approximately 2.5 X 10 00000 dpm, varying amounts of phenylethanolamine and unlabeled S-adenosyl-L-methionine, 20 microl enzyme and water at 30°C.
0.0028
phenylethanolamine
mutant E185A, assay mixture consists of 25 microl of 0.5 M phosphate buffer (pH 8.0), 5 microl of [methyl-3H]S-adenosyl-L-methionine containing approximately 2.5 X 10 00000 dpm, varying amounts of phenylethanolamine and unlabeled S-adenosyl-L-methionine, 20 microl enzyme and water at 30°C.
0.0142
phenylethanolamine
mutant E185D, assay mixture consists of 25 microl of 0.5 M phosphate buffer (pH 8.0), 5 microl of [methyl-3H]S-adenosyl-L-methionine containing approximately 2.5 X 10 00000 dpm, varying amounts of phenylethanolamine and unlabeled S-adenosyl-L-methionine, 20 microl enzyme and water at 30°C.
0.0175
phenylethanolamine
mutant Y35F, assay mixture consists of 25 microl of 0.5 M phosphate buffer (pH 8.0), 5 microl of [methyl-3H]S-adenosyl-L-methionine containing approximately 2.5 X 10 00000 dpm, varying amounts of phenylethanolamine and unlabeled S-adenosyl-L-methionine, 20 microl enzyme and water at 30°C.
0.043
phenylethanolamine
wild type enzyme, assay mixture consists of 25 microl of 0.5 M phosphate buffer (pH 8.0), 5 microl of [methyl-3H]S-adenosyl-L-methionine containing approximately 2.5 X 10 00000 dpm, varying amounts of phenylethanolamine and unlabeled S-adenosyl-L-methionine, 20 microl enzyme and water at 30°C.
0.045
phenylethanolamine
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purified in the absence of reducing agent, dimer, His-tagged
0.0483
phenylethanolamine
mutant D267A, assay mixture consists of 25 microl of 0.5 M phosphate buffer (pH 8.0), 5 microl of [methyl-3H]S-adenosyl-L-methionine containing approximately 2.5 X 10 00000 dpm, varying amounts of phenylethanolamine and unlabeled S-adenosyl-L-methionine, 20 microl enzyme and water at 30°C.
