2.1.1.320: type II protein arginine methyltransferase

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For detailed information about type II protein arginine methyltransferase, go to the full flat file.

Reaction

2 S-adenosyl-L-methionine +

Synonyms

At4g31120, EC 2.1.1.124, EC 2.1.1.125, EC 2.1.1.126, EC 2.1.1.23, Hsl7, Jak-binding protein 1, Janus kinase-binding protein 1, JBP1, PRMT-5, PRMT-9, PRMT15, PRMT5, PRMT7, PRMT9, protein arginine methyltransferase 5, Skb1

ECTree

     2 Transferases

         2.1 Transferring one-carbon groups

             2.1.1 Methyltransferases

                2.1.1.320 type II protein arginine methyltransferase

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1	Activating Compound
5693	AA Sequence
4	Application
4	Cloned(Commentary)
5	Crystallization (Commentary)
1867	Disease/ Diagnostics
6	Expression
38	General Information
58	IC50 Value
59	Inhibitors
4	KM Value [mM]
19	Localization
6	Molecular Weight [Da]
15	Natural Substrates/ Products (Substrates)
48	Organism
58	PDB ID
4	Protein Variants
1	Purification (Commentary)
3	Reaction
48	Reference
54	Source Tissue
66	Substrates and Products (Substrate)
4	Subunits
53	Synonyms
1	Systematic Name

Reaction

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Reaction on EC 2.1.1.320 - type II protein arginine methyltransferase

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REACTION

REACTION DIAGRAM

COMMENTARY

ORGANISM

UNIPROT

LITERATURE

2 S-adenosyl-L-methionine + [protein]-L-arginine = 2 S-adenosyl-L-homocysteine + [protein]-Nomega,Nomega'-dimethyl-L-arginine

overall reaction

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S-adenosyl-L-methionine + [protein]-L-arginine = S-adenosyl-L-homocysteine + [protein]-Nomega-methyl-L-arginine

(1a)

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S-adenosyl-L-methionine + [protein]-Nomega-methyl-L-arginine = S-adenosyl-L-homocysteine + [protein]-Nomega,Nomega'-dimethyl-L-arginine

(1b)

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