2.1.1.321: type III protein arginine methyltransferase

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For detailed information about type III protein arginine methyltransferase, go to the full flat file.

Reaction

Synonyms

EC 2.1.1.124, EC 2.1.1.125, EC 2.1.1.126, EC 2.1.1.23, PRMT-7, PRMT7, protein arginine methyltransferase 7

ECTree

     2 Transferases

         2.1 Transferring one-carbon groups

             2.1.1 Methyltransferases

                2.1.1.321 type III protein arginine methyltransferase

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Results	in table
1008	AA Sequence
1	Application
4	Cloned(Commentary)
3	Crystallization (Commentary)
24	Disease/ Diagnostics
1	Expression
21	General Information
2	Inhibitors
1	kcat/KM [mM/s]
1	KM Value [mM]
2	Localization
1	Metals/Ions
3	Molecular Weight [Da]
8	Natural Substrates/ Products (Substrates)
26	Organism
1	PDB ID
8	Protein Variants
3	Purification (Commentary)
1	Reaction
24	Reference
27	Source Tissue
37	Substrates and Products (Substrate)
2	Subunits
27	Synonyms
1	Systematic Name
3	Temperature Optimum [°C]
3	Temperature Range [°C]
1	Turnover Number [1/s]

Systematic Name

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Systematic Name on EC 2.1.1.321 - type III protein arginine methyltransferase

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SYSTEMATIC NAME

IUBMB Comments

S-adenosyl-L-methionine:[protein]-L-arginine N-methyltransferase ([protein]-Nomega-methyl-L-arginine-forming)

Type III protein arginine methyltransferases catalyse the single methylation of one of the terminal nitrogen atoms of the guanidino group in an L-arginine residue within a protein. Unlike type I and type II protein arginine methyltransferases, which also catalyse this reaction, type III enzymes do not methylate the substrate any further. cf. EC 2.1.1.319, type I protein arginine methyltransferase, EC 2.1.1.320, type II protein arginine methyltransferase, and EC 2.1.1.322, type IV protein arginine methyltransferase.