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2.1.1.34: tRNA (guanosine18-2'-O)-methyltransferase

This is an abbreviated version!
For detailed information about tRNA (guanosine18-2'-O)-methyltransferase, go to the full flat file.

Word Map on EC 2.1.1.34

Reaction

S-adenosyl-L-methionine
+
guanosine18 in tRNA
=
S-adenosyl-L-homocysteine
+
2'-O-methylguanosine18 in tRNA

Synonyms

methyltransferase, transfer ribonucleate guanosine 2'-, S-adenosyl-L-methionine:tRNA (guanosine-2'-O-)-methyltransferase, SpoU, TARBP1, transfer ribonucleate guanosine 2'-methyltransferase, transfer RNA (Gm18) methyltransferase, TrmH, tRNA (Gm18) 2'-O-methyltransferase, tRNA (Gm18) methyltransferase, tRNA (guanosine-2'-O-)-methyltransferase, tRNA Gm18 methyltransferase, tRNA guanosine 2'-methyltransferase

ECTree

     2 Transferases
         2.1 Transferring one-carbon groups
             2.1.1 Methyltransferases
                2.1.1.34 tRNA (guanosine18-2'-O)-methyltransferase

KM Value

KM Value on EC 2.1.1.34 - tRNA (guanosine18-2'-O)-methyltransferase

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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.000006
Escherichia coli tRNA-Ile
-
-
-
0.000005
guanosine18 in Escherichia coli tRNA-Met
-
-
-
0.00001
guanosine18 in Escherichia coli tRNA-Phe
-
-
-
0.021 - 0.27
guanosine18 in tRNATyr
-
0.000005 - 0.00001
guanosine18 in yeast tRNA-Phe
-
0.00011 - 0.0013
guanosine18 in yeast tRNAPhe
-
0.000082
guanosine18 in yeast tRNAPhe mutant transcript
-
pH and temperature not specified in the publication, Vmax: 3.1 micromol/mg/h
-
0.0125
guanosine18 in yeast tRNAPhe-AGA mutant transcript
-
pH and temperature not specified in the publication, Vmax: 0.00675 micromol/mg/h
-
0.00082
guanosine18 in yeast tRNAPhe-dG18 mutant transcript
-
pH and temperature not specified in the publication, Vmax: 0.1 micromol/mg/h
-
0.0002
guanosine18 in yeast tRNAPhe-GAA mutant transcript
-
pH and temperature not specified in the publication, Vmax: 0.135 micromol/mg/h
-
0.000245
guanosine18 in yeast tRNAPhe-GGA mutant transcript
-
pH and temperature not specified in the publication, Vmax: 1.2 micromol/mg/h
-
0.0003
guanosine18 in yeast tRNAPhe-GUA mutant transcript
-
pH and temperature not specified in the publication, Vmax: 0.18 micromol/mg/h
-
0.00047 - 28
S-adenosyl-L-methionine
additional information
additional information
-