2.1.1.57: methyltransferase cap1

This is an abbreviated version!
For detailed information about methyltransferase cap1, go to the full flat file.

Word Map on EC 2.1.1.57

2.1.1.57

sars-cov-2

coronaviruses

2'-o-methylation

non-structural

flaviviruses

sinefungin

coronaviridae

2'-o-ribose

adomet-dependent

nsp8

n7-mtase

3clpro

replication-transcription

guanine-n7

guanine-n7-methyltransferase

analysis

medicine

Reaction

a 5'-(N7-methyl 5'-triphosphoguanosine)-(ribonucleotide)-[mRNA]

a 5'-(N7-methyl 5'-triphosphoguanosine)-(2'-O-methyl-ribonucleotide)-[mRNA]

Synonyms

(nucleoside-2'-O-)-methyltransferase, (nucleoside-2'O)-methyltransferase, 2'-O methyltransferase, 2'-O MTase, 2'-O-methyltransferase, 2'-O-MTase, 2'O methyltransferase, 2'O-MTase, 2'OMTases, cap-specific 2'-O-methyltransferase, cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1, cap1 2-O'-ribose methyltransferase, CMTr1, EC 2.1.1.58, FtsJ methyltransferase domain-containing 2, FTSJD2, ISG95, KIAA0082, L protein domain VI, large polymerase protein domain VI, messenger ribonucleate nucleoside 2'-methyltransferase, messenger RNA (nucleoside-2'-)-methyltransferase, methyltransferase, messenger ribonucleate nucleoside 2'-, mRNA (nucleoside-2'-O)-methyltransferase, mRNA 5' cap-specific (nucleoside-2'-O)-methyltransferase, mRNA cap (nucleoside-2'-O)-methyltransferase, mRNA cap methyltransferase, mRNA cap-specific 2'-O-methyltransferase, MT57, Mtr1, nonstructural protein 16, nonstructural protein 16 methyltransferase, nonstructural protein 5 methyltransferase, NS5, NS5 MTase, NS5MTase, nsp10/16 complex, nsp10/nsp16 complex, nsp16, nsp16 protein, nsp16/nsp10 protein complex, ribose 2'-O methyltransferase, RNA (nucleoside-2'O)-methyltransferase, RNA cap 2'-O-methyltransferase, RNA cap 2'-O-MTase, RNA cap 2'O-MTase, RNA cap1 methyltransferase, RNA capping enzyme domain in protein A, S-adenosyl-L-methionine-dependent mRNA cap MTase, TbMT48, TbMT57, VP39, VP4

ECTree

2 Transferases

2.1 Transferring one-carbon groups

2.1.1 Methyltransferases

2.1.1.57 methyltransferase cap1

Advanced search results

Do not include text mining results

Include

results (more...)

Include

results (more...)

Results	in table
13	Activating Compound
2719	AA Sequence
7	Application
1	CAS Registry Number
17	Cloned(Commentary)
6	Crystallization (Commentary)
143	Disease/ Diagnostics
3	General Information
2	General Stability
5	IC50 Value
49	Inhibitors
15	Ki Value [mM]
12	KM Value [mM]
13	Localization
6	Metals/Ions
11	Molecular Weight [Da]
13	Natural Substrates/ Products (Substrates)
97	Organism
1	Pathway
164	PDB ID
9	pH Optimum
5	pH Range
3	pH Stability
111	Protein Variants
20	Purification (Commentary)
6	Reaction
1	Reaction Type
42	Reference
5	Source Tissue
3	Specific Activity [micromol/min/mg]
2	Storage Stability
83	Substrates and Products (Substrate)
8	Subunits
81	Synonyms
1	Systematic Name
5	Temperature Optimum [°C]
4	Temperature Stability [°C]

Natural Substrates Products

print visible entries

print all entries

Go back to the abbreviated version
of the Enzyme Summary Page.

Natural Substrates Products on EC 2.1.1.57 - methyltransferase cap1

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

top print hide

Go to Natural Substrate Search

S-adenosyl-L-methionine + 7Me-GpppA-C5

S-adenosyl-L-homocysteine + 7Me-GpppA-2'OMe-C5

2 entries

S-adenosyl-L-methionine + 7Me-GpppA-Cn

S-adenosyl-L-homocysteine + 7Me-GpppA-2'OMe-Cn

Dengue virus

exclusive methylation at the 2'O position

704920

S-adenosyl-L-methionine + a 5'-(N7-methyl 5'-triphosphoguanosine)-(purine-ribonucleotide)-[mRNA]

S-adenosyl-L-homocysteine + a 5'-(N7-methyl 5'-triphosphoguanosine)-(2'-O-methyl-purine-ribonucleotide)-[mRNA]

2 entries

S-adenosyl-L-methionine + GpppA-Cn

S-adenosyl-L-homocysteine + GpppA-2'OMe-Cn

Dengue virus

exclusive methylation at the 2'O position

704920

S-adenosyl-L-methionine + m7G(5')pppR-RNA

S-adenosyl-L-homocysteine + m7G(5')pppRm-RNA

4 entries

additional information

2 entries