2.1.1.85: protein-histidine N-methyltransferase
This is an abbreviated version!
For detailed information about protein-histidine N-methyltransferase, go to the full flat file.
Reaction
Synonyms
actin His73 nmethyltransferase, actin histidine methyltransferase, actin histidine-N3 methyltransferase, actin-specific histidine methyltransferase, actin-specific histidine N-methyltransferase, actin-specific methyltransferase, methyltransferase, protein (histidine), protein (actin) histidine MTase, protein methylase IV, S-adenosyl methionine:protein-histidine N-methyltransferase, SET domain protein 3, setd3
ECTree
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General Information
General Information on EC 2.1.1.85 - protein-histidine N-methyltransferase
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malfunction
physiological function
the enzyme plays important roles in hypoxic pulmonary hypertension, muscle differentiation, and carcinogenesis
enzyme depletion impairs signal-induced contraction in primary uterine smooth muscle cells
malfunction
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enzyme-deficient female mice have severely decreased litter sizes owing to primary maternal dystocia that is refractory to ecbolic induction agents