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2.3.1.206: 3,5,7-trioxododecanoyl-CoA synthase

This is an abbreviated version!
For detailed information about 3,5,7-trioxododecanoyl-CoA synthase, go to the full flat file.

Word Map on EC 2.3.1.206

Reaction

3 malonyl-CoA +

hexanoyl-CoA
= 3 CoA +
3,5,7-trioxododecanoyl-CoA
 + 3 CO2

Synonyms

OLA synthase, olivetol synthase, olivetol-forming PKS, OLS, PKS, polyketide synthase, tetraketide synthase, TKS, type III PKS, type III polyketide synthase

ECTree

     2 Transferases
         2.3 Acyltransferases
             2.3.1 Transferring groups other than aminoacyl groups
                2.3.1.206 3,5,7-trioxododecanoyl-CoA synthase

Crystallization

Crystallization on EC 2.3.1.206 - 3,5,7-trioxododecanoyl-CoA synthase

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CRYSTALLIZATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
cocrystallization of the enzyme with CoA (2 mM) is performed in 0.2 M potassium nitrate containing 20% w/v PEG 3350 for 72 h at 4 °C using the sitting drop vapour diffusion technique. Crystals are cryo-protected in the mother liquor containing 20% glycerol, followed by flash freezing in liquid nitrogen