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2.3.1.24: sphingosine N-acyltransferase

This is an abbreviated version!
For detailed information about sphingosine N-acyltransferase, go to the full flat file.

Word Map on EC 2.3.1.24

Reaction

an acyl-CoA
+
sphingosine
=
CoA
 +
a ceramide

Synonyms

(dihydro)ceramide synthase, acyl-CoA : sphingosine N-acyltramferase, acyl-CoA : sphingosine N-acyltransferase, acyltransferase, sphingosine, C16:0-CerS, CER2, Cer3, ceramide synthase, ceramide synthase 4, ceramide synthase 5, ceramide synthase 6, ceramide synthetase, CerS, CerS4, CerS45, CerS5, CerS6, CNAG_02086, CNAG_02087, CNAG_06717, DLag1, Drosophila longevitiy assurance gene-1 homologue, fatty acyl-CoA:sphingosine acyltransferase, LAC1, LAG1, LAG1 longevity assurance homolog 2, LAG1 longevity assurance homolog 5, LAG12, LASS5, Lass6, LOH2, longevity assurance homolog 5, longevity assurance homolog 6, longevity assurance homologue 5, longevity assurance homologue 6, More, schlank, SpAT, sphinganine N-acyl transferase synthase, sphinganine N-acyltransferase, sphingosine acyltransferase, sphingosine N-acyltransferase, sphingosine/sphinganine acyltransferase, TcCerS, TcCERS1, TRAM homolog 4, translocating chain-associating membrane protein homolog 4, trh1-like, trh4

ECTree

     2 Transferases
         2.3 Acyltransferases
             2.3.1 Transferring groups other than aminoacyl groups
                2.3.1.24 sphingosine N-acyltransferase

Natural Substrates Products

Natural Substrates Products on EC 2.3.1.24 - sphingosine N-acyltransferase

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NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
acyl-CoA + sphingosine
?
show the reaction diagram
LASS5 is the major ceramide synthase gene product involved in sphingolipid production that may also regulate PtdCho metabolism in pulmonary epithelia
-
-
?
D-sphingosine + palmitoyl-CoA
N-palmitoyl-D-sphingosine + CoA
show the reaction diagram
-
-
-
?
dihydrosphingosine + myristoyl-CoA
N-myristoyldihydrosphingosine + CoA
show the reaction diagram
-
-
-
?
dihydrosphingosine + palmitoyl-CoA
N-palmitoyldihydrosphingosine + CoA
show the reaction diagram
dihydrosphingosine + stearoyl-CoA
N-stearoyldihydrosphingosine + CoA
show the reaction diagram
-
-
-
?
palmitoyl-CoA + sphinganine
CoA + N-palmitoylsphinganine
show the reaction diagram
-
-
-
?
palmitoyl-CoA + sphingosine
CoA + N-palmitoylsphingosine
show the reaction diagram
-
-
-
?
sphinganine + arachidoyl-CoA
N-arachidoylsphinganine + CoA
show the reaction diagram
-
-
-
?
sphinganine + palmitoyl-CoA
N-palmitoyl-DL-dihydrosphingosine + CoA
show the reaction diagram
-
-
-
-
?
sphinganine + palmitoyl-CoA
N-palmitoyldihydrosphingosine + CoA
show the reaction diagram
-
-
-
-
?
sphinganine + palmitoyl-CoA
N-palmitoylsphinganine + CoA
show the reaction diagram
sphinganine + stearoyl-CoA
N-stearoylsphinganine + CoA
show the reaction diagram
sphingosine + behenoyl-CoA
N-behenoylsphingosine + CoA
show the reaction diagram
-
-
-
?
sphingosine + eicosanoyl-CoA
N-eicosanoylsphingosine + CoA
show the reaction diagram
-
-
-
?
sphingosine + palmitoyl-CoA
N-palmitoylsphingosine + CoA
show the reaction diagram
sphingosine + stearoyl-CoA
N-stearoylsphingosine + CoA
show the reaction diagram
additional information
?
-