2.4.1.217: mannosyl-3-phosphoglycerate synthase

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For detailed information about mannosyl-3-phosphoglycerate synthase, go to the full flat file.

Reaction

Synonyms

mannosyl-3-P-glycerate synthase, mannosyl-3-phosphoglycerate phosphatase, mannosyl-3-phosphoglycerate synthase, mannosyl-3-phosphoglycerate synthase/phosphatase, mannosylglycerate synthase, MGSD, MPG synthase, MPGP, MPGS, MPGS/GPGS, MpgS/P, synthase, mannosyl-3-phosphoglycerate

ECTree

     2 Transferases

         2.4 Glycosyltransferases

             2.4.1 Hexosyltransferases

                2.4.1.217 mannosyl-3-phosphoglycerate synthase

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Results	in table
1	Activating Compound
217	AA Sequence
1	CAS Registry Number
16	Cloned(Commentary)
5	Crystallization (Commentary)
23	General Information
1	General Stability
12	Inhibitors
21	KM Value [mM]
36	Metals/Ions
11	Molecular Weight [Da]
32	Natural Substrates/ Products (Substrates)
112	Organism
5	Pathway
30	PDB ID
13	pH Optimum
5	pH Range
1	Posttranslational Modification
3	Protein Variants
9	Purification (Commentary)
5	Reaction
3	Reaction Type
27	Reference
5	Specific Activity [micromol/min/mg]
52	Substrates and Products (Substrate)
18	Subunits
41	Synonyms
1	Systematic Name
13	Temperature Optimum [°C]
7	Temperature Range [°C]
18	Temperature Stability [°C]
2	Turnover Number [1/s]

Specific Activity

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Specific Activity on EC 2.4.1.217 - mannosyl-3-phosphoglycerate synthase

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SPECIFIC ACTIVITY [µmol/min/mg]

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

0.0232

Rubrobacter xylanophilus

B7SY86

with GDP-mannose as a substrate

710004

0.4

Thermus thermophilus HB27

Q84B24

with Zn2+ as a cofactor

709105

156

Rhodothermus marinus

Q6WSQ4

purified enzyme lacking the 30 amino acids of the C-terminus

659444

45

Thermus thermophilus HB27

Q84B24

with Mg2+ as a cofactor

709105

5.3

Thermus thermophilus HB27

Q84B24

when 20 mM Mg2+ is added in combination with Zn2+ (300 microM), the MpgS specific activity recovered substantially

709105