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2.4.2.21: nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase

This is an abbreviated version!
For detailed information about nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, go to the full flat file.

Word Map on EC 2.4.2.21

Reaction

beta-nicotinate D-ribonucleotide
+
5,6-Dimethylbenzimidazole
=
nicotinate
+
alpha-ribazole 5'-phosphate
+
H+

Synonyms

5,6-dimethylbenzimidazole phosphoribosyltransferase, ArsAB, CblT, CobT, CobT2, N(1)-alpha-phosphoribosyltransferase, N1-alpha-phosphoribosyltransferase, NaMN:DMB phosphoribosyltransferase, nicotinate mononucleotide-dimethylbenzimidazole phosphoribosyltransferase, nicotinate mononucleotide:5,6-dimethylbenzimidazolyl phosphoribosyltransferase, nicotinate ribonucleotide:benzimidazole (adenine) phosphoribosyltransferase, NN:DBI PRT, phosphoribosyltransferase, nicotinate mononucleotide-dimethylbenzimidazole, SoArsAB

ECTree

     2 Transferases
         2.4 Glycosyltransferases
             2.4.2 Pentosyltransferases
                2.4.2.21 nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase

Cloned

Cloned on EC 2.4.2.21 - nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase

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CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
expressed as fusion protein BluB/CobT2 in Escherichia coli KRX cells
expressed in Escherichia coli
expressed in Salmonella enterica lacking the CobT enzyme
-
gene cobT, comparison with homologues
-
wild-type and mutants cloned into vector pSU18 or vector pT7-5. Plasmids carrying wild-type or mutant cobT alleles introduced into strain JE2607 (cobT cobB recA) or strain JE2423 (cobT recA). Plasmids encoding mutant cobT alleles under the control of the T7 promoter of vector pT7-5 transformed into strain JE2017 and overexpressed