2.5.1.68: (2Z,6E)-farnesyl diphosphate synthase

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For detailed information about (2Z,6E)-farnesyl diphosphate synthase, go to the full flat file.

Word Map on EC 2.5.1.68

2.5.1.68

tuberculosis

synthases

decaprenyl

allylic

lipoarabinomannan

neryl

chain-length

isoprene

mycolyl-arabinogalactan-peptidoglycan

cis-prenyltransferase

Reaction

Synonyms

cis-farnesyl diphosphate synthase, cis-FPS, Mvan 4662, omega,E,Z-FPP, Rv1086, short (C15) chain Z-isoprenyl diphosphate synthase, Z,E-FPP synthase, Z-farnesyl diphosphate synthase, Z-FPP synthase, ZPT1

ECTree

2 Transferases

2.5 Transferring alkyl or aryl groups, other than methyl groups

2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)

2.5.1.68 (2Z,6E)-farnesyl diphosphate synthase

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Results	in table
42	AA Sequence
1	CAS Registry Number
10	Cloned(Commentary)
2	Crystallization (Commentary)
7	Inhibitors
8	kcat/KM [mM/s]
15	KM Value [mM]
6	Localization
7	Metals/Ions
3	Molecular Weight [Da]
8	Natural Substrates/ Products (Substrates)
593	Organism
3	Pathway
6	PDB ID
8	pH Optimum
1	pH Range
13	Protein Variants
7	Purification (Commentary)
1	Reaction
21	Reference
5	Specific Activity [micromol/min/mg]
32	Substrates and Products (Substrate)
7	Subunits
28	Synonyms
1	Systematic Name
7	Temperature Optimum [°C]
8	Turnover Number [1/s]

Cloned

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Cloned on EC 2.5.1.68 - (2Z,6E)-farnesyl diphosphate synthase

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2 entries

expressed in Escherichia coli BL21(DE3) cells

3 entries

expressed in Escherichia coli SN-IRv cells

Mycobacterium tuberculosis

P9WFF5

738977

expression in Escherichia coli

3 entries

Rv1086, DNA and amino acid sequence determination and anaylsis, overexpression in Mycobacterium smegmatis cytosol and membranes, the transformed cells show a 5fold increased enzyme activity

Mycobacterium tuberculosis

669190