2.5.1.68: (2Z,6E)-farnesyl diphosphate synthase

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For detailed information about (2Z,6E)-farnesyl diphosphate synthase, go to the full flat file.

Reaction

Synonyms

cis-farnesyl diphosphate synthase, cis-FPS, Mvan 4662, omega,E,Z-FPP, Rv1086, short (C15) chain Z-isoprenyl diphosphate synthase, Z,E-FPP synthase, Z-farnesyl diphosphate synthase, Z-FPP synthase, ZPT1

ECTree

     2 Transferases

         2.5 Transferring alkyl or aryl groups, other than methyl groups

             2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)

                2.5.1.68 (2Z,6E)-farnesyl diphosphate synthase

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Results	in table
42	AA Sequence
1	CAS Registry Number
10	Cloned(Commentary)
2	Crystallization (Commentary)
7	Inhibitors
8	kcat/KM [mM/s]
15	KM Value [mM]
6	Localization
7	Metals/Ions
3	Molecular Weight [Da]
8	Natural Substrates/ Products (Substrates)
593	Organism
3	Pathway
6	PDB ID
8	pH Optimum
1	pH Range
13	Protein Variants
7	Purification (Commentary)
1	Reaction
21	Reference
5	Specific Activity [micromol/min/mg]
32	Substrates and Products (Substrate)
7	Subunits
28	Synonyms
1	Systematic Name
7	Temperature Optimum [°C]
8	Turnover Number [1/s]

KM Value

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KM Value on EC 2.5.1.68 - (2Z,6E)-farnesyl diphosphate synthase

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KM VALUE [mM]

SUBSTRATE

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

0.038

(E)-geranyl diphosphate

Mycobacterium tuberculosis

-

pH 7.9, 37°C

669192

0.016

(E)-neryl diphosphate

Mycobacterium tuberculosis

-

pH 7.9, 37°C

669192

0.0023 - 0.15

geranyl diphosphate

7 entries

0.0012 - 0.124

isopentenyl diphosphate

6 entries

0.0023

geranyl diphosphate

Thermobifida fusca

-

pH 7.5, 37°C

690753

0.0041

geranyl diphosphate

Corynebacterium efficiens

-

pH 7.5, 37°C

690753

0.0068

geranyl diphosphate

Corynebacterium glutamicum

-

pH 7.5, 37°C

690753

0.0078

geranyl diphosphate

Mycobacterium tuberculosis

-

pH 7.5, 37°C

690753

0.0078

geranyl diphosphate

Mycobacterium tuberculosis

P9WFF5

pH and temperature not specified in the publication

738977

0.15

geranyl diphosphate

Mycobacterium tuberculosis

P9WFF5

mutant L84A/L85F

705121

0.15

geranyl diphosphate

Mycobacterium tuberculosis

P9WFF5

pH 7.9, 37°C, mutant enzyme L84A/L85F

705121

0.0012

isopentenyl diphosphate

Thermobifida fusca

-

pH 7.5, 37°C

690753

0.0027

isopentenyl diphosphate

Corynebacterium efficiens

-

pH 7.5, 37°C

690753

0.0045

isopentenyl diphosphate

Mycobacterium tuberculosis

-

pH 7.5, 37°C

690753

0.0045

isopentenyl diphosphate

Mycobacterium tuberculosis

P9WFF5

pH and temperature not specified in the publication

738977

0.0067

isopentenyl diphosphate

Corynebacterium glutamicum

-

pH 7.5, 37°C

690753

0.124

isopentenyl diphosphate

Mycobacterium tuberculosis

-

pH 7.9, 37°C

669192