2.5.1.83: hexaprenyl diphosphate synthase [(2E,6E)-farnesyl-diphosphate specific]
This is an abbreviated version!
For detailed information about hexaprenyl diphosphate synthase [(2E,6E)-farnesyl-diphosphate specific], go to the full flat file.
Reaction
+ 3 isopentenyl diphosphate = 3 diphosphate +
Synonyms
C30PP synthase, COQ1, Coq1p, EC 2.5.1.33, hexaprenyl pyrophosphate synthetase, hexaprenyl-diphosphate synthase [(2E,6E)-farnesyl-diphosphate specific], HexPP synthase, HexPPs, HexPS
ECTree
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Substrates Products
Substrates Products on EC 2.5.1.83 - hexaprenyl diphosphate synthase [(2E,6E)-farnesyl-diphosphate specific]
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REACTION DIAGRAM
(2E,6E)-farnesyl diphosphate + 1 but-3-enyl diphosphate
diphosphate + (E)-norgeranylgeranyl diphosphate
(2E,6E)-farnesyl diphosphate + 3 isopentenyl diphosphate
3 diphosphate + all-trans-hexaprenyl diphosphate
(2E,6E)-farnesyl diphosphate + 3-ethylbut-3-enyl diphosphate
diphosphate + (all-E)-3-ethyl-7,11,15-trimethylhexadeca-2,6,10,14-tetraenyl diphosphate + (all-E)-3,7-diethyl-11,15,19-trimethyleicosa-2,6,10,14,18-pentaenyl diphosphate
(2E,6E)-farnesyl diphosphate + 3-ethylbut-3-enyl diphosphate
diphosphate + (all-E)-3-ethyl-7,11,15-trimethylhexadeca-2,6,10,14-tetraenyl diphosphate + (all-E)-3,7-diethyl-11,15,19-trimethylicosa-2,6,10,14,18-pentaenyl diphosphate
(2E,6E)-farnesyl diphosphate + but-3-enyl diphosphate
diphosphate + (E)-norgeranylgeranyl diphosphate
(2E,6E)-farnesyl diphosphate + isopentenyl diphosphate
diphosphate + all-trans-hexaprenyl diphosphate + heptaprenyl diphosphate
-
-
-
-
?
geranyl diphosphate + 4 isopentenyl diphosphate
4 diphosphate + all-trans-hexaprenyl diphosphate
geranylgeranyl diphosphate + 2 isopentenyl diphosphate
2 diphosphate + all-trans-hexaprenyl diphosphate
diphosphate + (E)-norgeranylgeranyl diphosphate
-
-
-
?
(2E,6E)-farnesyl diphosphate + 1 but-3-enyl diphosphate
diphosphate + (E)-norgeranylgeranyl diphosphate
-
-
-
?
3 diphosphate + all-trans-hexaprenyl diphosphate
-
-
-
?
(2E,6E)-farnesyl diphosphate + 3 isopentenyl diphosphate
3 diphosphate + all-trans-hexaprenyl diphosphate
the enzyme prefers farnesyl diphosphate to geranylgeranyl diphosphate (activity is 3fold higher) as an allylic substrate and does not show activity for geranyl diphosphate and dimethylallyl diphosphate
-
-
?
(2E,6E)-farnesyl diphosphate + 3 isopentenyl diphosphate
3 diphosphate + all-trans-hexaprenyl diphosphate
the enzyme prefers farnesyl diphosphate to geranylgeranyl diphosphate (activity is 3fold higher) as an allylic substrate and does not show activity for geranyl diphosphate and dimethylallyl diphosphate
-
-
?
(2E,6E)-farnesyl diphosphate + 3 isopentenyl diphosphate
3 diphosphate + all-trans-hexaprenyl diphosphate
-
-
-
?
(2E,6E)-farnesyl diphosphate + 3 isopentenyl diphosphate
3 diphosphate + all-trans-hexaprenyl diphosphate
-
-
-
-
?
(2E,6E)-farnesyl diphosphate + 3 isopentenyl diphosphate
3 diphosphate + all-trans-hexaprenyl diphosphate
-
-
-
-
?
diphosphate + (all-E)-3-ethyl-7,11,15-trimethylhexadeca-2,6,10,14-tetraenyl diphosphate + (all-E)-3,7-diethyl-11,15,19-trimethyleicosa-2,6,10,14,18-pentaenyl diphosphate
-
-
-
?
(2E,6E)-farnesyl diphosphate + 3-ethylbut-3-enyl diphosphate
diphosphate + (all-E)-3-ethyl-7,11,15-trimethylhexadeca-2,6,10,14-tetraenyl diphosphate + (all-E)-3,7-diethyl-11,15,19-trimethyleicosa-2,6,10,14,18-pentaenyl diphosphate
-
-
-
?
diphosphate + (all-E)-3-ethyl-7,11,15-trimethylhexadeca-2,6,10,14-tetraenyl diphosphate + (all-E)-3,7-diethyl-11,15,19-trimethylicosa-2,6,10,14,18-pentaenyl diphosphate
-
-
-
?
(2E,6E)-farnesyl diphosphate + 3-ethylbut-3-enyl diphosphate
diphosphate + (all-E)-3-ethyl-7,11,15-trimethylhexadeca-2,6,10,14-tetraenyl diphosphate + (all-E)-3,7-diethyl-11,15,19-trimethylicosa-2,6,10,14,18-pentaenyl diphosphate
-
-
-
?
?
-
-
-
?
(2E,6E)-farnesyl diphosphate + 3-propylbut-3-enyl diphosphate
?
-
-
-
?
diphosphate + (E)-norgeranylgeranyl diphosphate
-
-
-
?
(2E,6E)-farnesyl diphosphate + but-3-enyl diphosphate
diphosphate + (E)-norgeranylgeranyl diphosphate
-
-
-
?
4 diphosphate + all-trans-hexaprenyl diphosphate
geranyl diphosphate is a poor substrate
-
-
?
geranyl diphosphate + 4 isopentenyl diphosphate
4 diphosphate + all-trans-hexaprenyl diphosphate
geranyl diphosphate is a poor substrate
-
-
?
2 diphosphate + all-trans-hexaprenyl diphosphate
-
-
-
?
geranylgeranyl diphosphate + 2 isopentenyl diphosphate
2 diphosphate + all-trans-hexaprenyl diphosphate
the enzyme prefers farnesyl diphosphate to geranylgeranyl diphosphate (activity is 3fold higher) as an allylic substrate and does not show activity for geranyl diphosphate and dimethylallyl diphosphate
-
-
?
geranylgeranyl diphosphate + 2 isopentenyl diphosphate
2 diphosphate + all-trans-hexaprenyl diphosphate
the enzyme prefers farnesyl diphosphate to geranylgeranyl diphosphate (activity is 3fold higher) as an allylic substrate and does not show activity for geranyl diphosphate and dimethylallyl diphosphate
-
-
?
geranylgeranyl diphosphate + 2 isopentenyl diphosphate
2 diphosphate + all-trans-hexaprenyl diphosphate
-
-
-
?
?
-
no activity with 3-butylbut-3-enyl diphosphate, norfarnesyl diphosphate or norgeranylgeranyl diphosphate
-
-
?
additional information
?
-
norfarnesyl diphosphate is not accepted as substrate
-
-
?
additional information
?
-
norfarnesyl diphosphate is not accepted as substrate
-
-
?
additional information
?
-
no activity with 3-butylbut-3-enyl diphosphate, norfarnesyl diphosphate or norgeranylgeranyl diphosphate
-
-
?