2.7.1.108: dolichol kinase

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For detailed information about dolichol kinase, go to the full flat file.

Reaction

Synonyms

At3g45040, AtDOK1, cytidine-5-triphosphate (CTP) dependent dolichol kinase, DK, DK1, DOK1, dolichol kinase, dolichol kinase 1, dolichol phosphokinase, dolichol-specific kinase, DOLK, SEC59, Sec59p

ECTree

     2 Transferases

         2.7 Transferring phosphorus-containing groups

             2.7.1 Phosphotransferases with an alcohol group as acceptor

                2.7.1.108 dolichol kinase

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Results	in table
17	Activating Compound
2592	AA Sequence
1	CAS Registry Number
7	Cloned(Commentary)
7	Cofactor
32	Disease/ Diagnostics
18	General Information
24	Inhibitors
1	Ki Value [mM]
18	KM Value [mM]
38	Localization
40	Metals/Ions
2	Molecular Weight [Da]
23	Natural Substrates/ Products (Substrates)
693	Organism
5	Pathway
12	pH Optimum
4	pH Range
34	Protein Variants
2	Purification (Commentary)
1	Reaction
6	Reaction Type
37	Reference
40	Source Tissue
5	Specific Activity [micromol/min/mg]
5	Storage Stability
48	Substrates and Products (Substrate)
24	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]

pH Range

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pH Range on EC 2.7.1.108 - dolichol kinase

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pH RANGE

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

4 - 10

Rattus norvegicus

-

about half-maximal activity at pH 6.0 and 8.0

640391

4 - 11

Glycine max

-

no second optimum with Tris-HCl, activity increases fairly linearly between pH 8.0 and 10.0, activity decreases about 25% between pH 9.5 and 10.0 in Chaps buffer

640398

6.6 - 10.2

Bos taurus

-

broad pH-activity profile with good activity observed from pH 7.0-10.0, about half-maximal activity at pH 6.6 and 10.2

640392

6.6 - 9.6

Tetrahymena pyriformis

-

2 optima, about half-maximal activity at pH 6.6, pH 8.5 and pH 9.6

640394