2.7.7.24: glucose-1-phosphate thymidylyltransferase

This is an abbreviated version!
For detailed information about glucose-1-phosphate thymidylyltransferase, go to the full flat file.

Reaction

Synonyms

Cps23FL, Cps2L, D-glucose-1-phosphate thymidylyltransferase, DnmL, dTDP-alpha-D-glucose pyrophosphorylase, dTDP-D-glucose synthase, dTDP-glucose synthase, dTDP-glucose-pyrophosphorylase, dTDPglucose pyrophosphorylase, Glc-1-P thymidylyltransferase, Glc-1-P TTase, Glc-1-P-TT, Glc1P-thymidylyltransferase, glucose 1-phosphate thymidylyltransferase, glucose-1-phosphate thymidylyltransferase, RfbA, rml-1, RmlA, RmlA protein, SchS6, SgcA1, ST0452, sugar-1-phosphate nucleotidyltransferase, TDP-glucose pyrophosphorylase, thymidine diphosphate glucose pyrophosphorylase, thymidine diphosphoglucose pyrophosphorylase, thymidylyltransferase, glucose 1-phosphate, ugpG, UgpG protein, UTP/dTTP-glucose-1-phosphate uridylyl/thymidylyl transferase

ECTree

     2 Transferases

         2.7 Transferring phosphorus-containing groups

             2.7.7 Nucleotidyltransferases

                2.7.7.24 glucose-1-phosphate thymidylyltransferase

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Results	in table
35934	AA Sequence
4	Application
1	CAS Registry Number
28	Cloned(Commentary)
7	Crystallization (Commentary)
11	General Information
3	IC50 Value
17	Inhibitors
16	kcat/KM [mM/s]
3	Ki Value [mM]
77	KM Value [mM]
40	Metals/Ions
11	Molecular Weight [Da]
35	Natural Substrates/ Products (Substrates)
101	Organism
30	Pathway
188	PDB ID
13	pH Optimum
4	pH Range
42	Protein Variants
29	Purification (Commentary)
2	Reaction
1	Reaction Type
56	Reference
3	Source Tissue
14	Specific Activity [micromol/min/mg]
4	Storage Stability
149	Substrates and Products (Substrate)
14	Subunits
73	Synonyms
1	Systematic Name
12	Temperature Optimum [°C]
3	Temperature Range [°C]
6	Temperature Stability [°C]
57	Turnover Number [1/s]

Storage Stability

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Storage Stability on EC 2.7.7.24 - glucose-1-phosphate thymidylyltransferase

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STORAGE STABILITY

ORGANISM

UNIPROT

LITERATURE

-20°C at concentrations higher than 5 mg/ml stable for up to three months

Escherichia coli

-

643081

-80 °C, 50 mM potassium phosphate buffer, pH 7.0, containing 1 mM DTT and 20% glycerol, purified SgcA1 is stable for several months with minimal loss of activity

Streptomyces globisporus

-

662671

4°C, stable for weeks

Pyrococcus horikoshii

-

761065

stable for several weeks at any step of purification if kept frozen

Pseudomonas aeruginosa

-

643079