1.1.1.303: diacetyl reductase [(R)-acetoin forming]
This is an abbreviated version!
For detailed information about diacetyl reductase [(R)-acetoin forming], go to the full flat file.
Reaction
Synonyms
(R,R)-BDH, (R,R)-butane-2,3-diol dehydrogenase, (R,R)-butanediol dehydrogenase/diacetyl reductase, acetoin/diacetyl reductase, BdhA, DAR, dudA, EC 1.1.1.5, gutB, More
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Engineering
Engineering on EC 1.1.1.303 - diacetyl reductase [(R)-acetoin forming]
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additional information
knockout of diacetyl reductase (DAR) gene dudA in Paenibacillus polymyxa strain ZJ-9 via homologous recombination between the genome and the previously constructed targeting vector pRN5101-L'C in a process based on homologous single-crossover. Disruption mutant Paenibacillus polymyxa ZJ-9-DELTAdudA is used for production of (R,R)-2,3-butanediol of ultra-high optical purity, and without parts of meso-2,3-butanediol, through (R,R)-butanediol dehydrogenase (EC 1.1.1.4). Paenibacillus polymyxa is a microorganism with a reported potential for the industrial production of (R,R)-2,3-butanediol. Gene dudA, the gene encoding DAR, is the key factor responsible for the formation of meso-2,3-butanediol, thus reducing the purity of (R,R)-2,3-butanediol
additional information
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knockout of diacetyl reductase (DAR) gene dudA in Paenibacillus polymyxa strain ZJ-9 via homologous recombination between the genome and the previously constructed targeting vector pRN5101-L'C in a process based on homologous single-crossover. Disruption mutant Paenibacillus polymyxa ZJ-9-DELTAdudA is used for production of (R,R)-2,3-butanediol of ultra-high optical purity, and without parts of meso-2,3-butanediol, through (R,R)-butanediol dehydrogenase (EC 1.1.1.4). Paenibacillus polymyxa is a microorganism with a reported potential for the industrial production of (R,R)-2,3-butanediol. Gene dudA, the gene encoding DAR, is the key factor responsible for the formation of meso-2,3-butanediol, thus reducing the purity of (R,R)-2,3-butanediol
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