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1.1.1.418: plant 3beta-hydroxysteroid-4alpha-carboxylate 3-dehydrogenase (decarboxylating)

This is an abbreviated version!
For detailed information about plant 3beta-hydroxysteroid-4alpha-carboxylate 3-dehydrogenase (decarboxylating), go to the full flat file.

Reaction

a 3beta-hydroxysteroid-4alpha-carboxylate
+
NAD+
=
a 3-oxosteroid
 +
CO2
 +
NADH

Synonyms

3beta-HSD/D1, 3beta-HSD/D2, 3beta-hydroxysteroid dehydrogenase/C-4 decarboxylase, 3beta-hydroxysteroid dehydrogenases/C-4 decarboxylase, 3beta-hydroxysteroid-dehydrogenase/C4-decarboxylase, 3betaHSD/D, 3betaHSD/D1, 3betaHSD/D2, 4alpha-carboxysterol-C3-dehydrogenase/C4-decarboxylase, 4alpha-CD

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.418 plant 3beta-hydroxysteroid-4alpha-carboxylate 3-dehydrogenase (decarboxylating)

Substrates Products

Substrates Products on EC 1.1.1.418 - plant 3beta-hydroxysteroid-4alpha-carboxylate 3-dehydrogenase (decarboxylating)

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
3alpha-deutero-4alpha-carboxy-cholest-7-en-3beta-ol + NAD+
? + CO2 + NADH + H+
show the reaction diagram
-
-
-
?
3beta-hydroxy,4alpha-carboxy-4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-sterol + NAD+
4alpha,14-dimethyl-5alpha,9beta-9,19-cycloergost-24(28)-en-3beta-ol + CO2 + NADH + H+
show the reaction diagram
-
-
-
-
?
4alpha-carboxy-4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-cholest-24-en-3beta-ol + NAD+
cholest-7-en-3-one + CO2 + NADH + H+
show the reaction diagram
-
-
-
-
?
4alpha-carboxy-4beta,14alpha-dimethyl-9beta,19-cycloergost-24(241)-en-3beta-ol + NAD+
4alpha,14alpha-dimethyl-9beta,19-cyclo-ergost-24(241)-en-3-one + CO2 + NADH + H+
show the reaction diagram
-
-
-
?
4alpha-carboxy-4beta-methyl-cholest-8,24-dien-3beta-ol + NAD+
4alpha-methyl-cholest-8,24-dien-3-one + CO2 + NADH + H+
show the reaction diagram
-
-
-
?
4alpha-carboxy-4beta-methyl-cholest-8,24-dien-3beta-ol + NAD+
? + CO2 + NADH + H+
show the reaction diagram
-
-
-
-
?
4alpha-carboxy-5alpha-stigmastane-3beta-ol + NAD+
stigmastane-3-one + CO2 + NADH + H+
show the reaction diagram
-
-
-
-
?
4alpha-carboxy-cholest-7-en-3alpha-ol + NAD+
cholest-7-en-3-one + CO2 + NADH + H+
show the reaction diagram
-
-
-
?
4alpha-carboxy-cholest-7-en-3beta-ol + NAD+
? + CO2 + NADH + H+
show the reaction diagram
-
-
-
-
?
4alpha-carboxy-cholest-7-en-3beta-ol + NAD+
cholest-7-en-3-one + CO2 + NADH + H+
show the reaction diagram
4alpha-carboxy-stigmasta-7,24(241)-dien-3beta-ol + NAD+
stigmasta-7,24(241)-dien-3-one + CO2 + NADH + H+
show the reaction diagram
-
-
-
?
4alpha-methyl-cholest-8,24-dien-3-one + NAD+
? + CO2 + NADH + H+
show the reaction diagram
-
-
-
-
?
4alpha-[242-3H]carboxy-5alpha-stigmasta-7,24(241)-dien-3beta-ol + NAD+
? + CO2 + NADH + H+
show the reaction diagram
-
-
-
-
?
4beta,14alpha-[241-3H]dimethyl-4alpha-carboxy-5alpha-ergosta-9beta,19-cyclo-24(241)-en-3beta-ol + NAD+
? + CO2 + NADH + H+
show the reaction diagram
-
-
-
-
?
a 3beta-hydroxysteroid-4alpa-carboxylate + NAD+
a 3-oxosteroid + CO2 + NADH + H+
show the reaction diagram
-
-
-
?
a 3beta-hydroxysteroid-4alpha-carboxylate + NAD+
a 3-oxosteroid + CO2 + NADH + H+
show the reaction diagram
-
-
-
-
?
additional information
?
-
-
the decarboxylation reaction is independent of molecular oxygen
-
-
?