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1.1.99.B9: (S)-2-hydroxycarboxylate dehydrogenase

This is an abbreviated version!
For detailed information about (S)-2-hydroxycarboxylate dehydrogenase, go to the full flat file.

Reaction

a (S)-2-hydroxycarboxylate
+
acceptor
=
a 2-oxocarboxylate
+
reduced acceptor

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.99 With unknown physiological acceptors
                1.1.99.B9 (S)-2-hydroxycarboxylate dehydrogenase

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Resultsin table
4Application
3Cofactor
2Expression
12KM Value [mM]
6Organism
1Reaction
6Reference
33Substrates and Products (Substrate)
1Systematic Name

KM Value

KM Value on EC 1.1.99.B9 - (S)-2-hydroxycarboxylate dehydrogenase

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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
81.2
(2S)-(2-chlorophenyl)(hydroxy)acetic acid
-
pH 8.0, 30°C
11.5
(2S)-(2-fluorophenyl)(hydroxy)acetic acid
-
pH 8.0, 30°C
4.9
(2S)-(3-chlorophenyl)(hydroxy)acetic acid
-
pH 8.0, 30°C
3.6
(2S)-(4-bromophenyl)(hydroxy)acetic acid
-
pH 8.0, 30°C
3.7
(2S)-(4-chlorophenyl)(hydroxy)acetic acid
-
pH 8.0, 30°C
66.5
(2S)-(4-fluorophenyl)(hydroxy)acetic acid
-
pH 8.0, 30°C
15.2
(2S)-hydroxy(2,4-difluorophenyl)acetic acid
-
pH 8.0, 30°C
8.6
(2S)-hydroxy(3,5-difluorophenyl)acetic acid
-
pH 8.0, 30°C
73.5
(2S)-hydroxy(4-hydroxyphenyl)acetic acid
-
pH 8.0, 30°C
65.6
(2S)-hydroxy(4-methylphenyl)acetic acid
-
pH 8.0, 30°C
64.9
(2S)-hydroxy(phenyl)acetic acid
-
pH 8.0, 30°C
68.5
(2S)-hydroxy-3-phenylpropanoic acid
-
pH 8.0, 30°C