1.12.1.5: hydrogen dehydrogenase [NAD(P)+]

This is an abbreviated version!
For detailed information about hydrogen dehydrogenase [NAD(P)+], go to the full flat file.

Reaction

H2
+
NAD(P)+
=
H+
+
NAD(P)H

Synonyms

H-II, hydrogenase II, SHI

ECTree

     1 Oxidoreductases
         1.12 Acting on hydrogen as donor
             1.12.1 With NAD+ or NADP+ as acceptor
                1.12.1.5 hydrogen dehydrogenase [NAD(P)+]

Systematic Name

Systematic Name on EC 1.12.1.5 - hydrogen dehydrogenase [NAD(P)+]

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SYSTEMATIC NAME
IUBMB Comments
hydrogen:NAD(P)+ oxidoreductase
A nickel, iron, iron-sulfur protein. The enzyme from the archaeon Pyrococcus furiosus is part of a heterotetrameric complex where the alpha and delta subunits function as a hydrogenase while the beta and gamma subunits function as sulfur reductase (EC 1.12.98.4, sulfhydrogenase). Different from EC 1.12.1.3, hydrogen dehydrogenase (NADP+).