1.14.11.B17: S-(L-glutamyl)-[peptidyl-carrier protein]-3-hydroxylase (3-hydroxylating, S-(threo-3-hydroxy-L-glutamyl)-[peptidyl-carrier-protein]-forming)

This is an abbreviated version, for detailed information about S-(L-glutamyl)-[peptidyl-carrier protein]-3-hydroxylase (3-hydroxylating, S-(threo-3-hydroxy-L-glutamyl)-[peptidyl-carrier-protein]-forming), go to the full flat file.

Reaction

S-(L-glutamyl)-[peptidyl-carrier protein of nonribosomal peptide synthetase KtzH]
+
2-oxoglutarate
+
O2
=
S-(threo-3-hydroxy-L-glutamyl)-[peptidyl-carrier-protein of nonribosomal peptide synthetase KtzH]
+
succinate
+
CO2

Synonyms

KtzO

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.11 With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor
                1.14.11.B17 S-(L-glutamyl)-[peptidyl-carrier protein]-3-hydroxylase (3-hydroxylating, S-(threo-3-hydroxy-L-glutamyl)-[peptidyl-carrier-protein]-forming)

Natural Substrates Products

Natural Substrates Products on EC 1.14.11.B17 - S-(L-glutamyl)-[peptidyl-carrier protein]-3-hydroxylase (3-hydroxylating, S-(threo-3-hydroxy-L-glutamyl)-[peptidyl-carrier-protein]-forming)

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NATURAL SUBSTRATES
NATURAL PRODUCTS
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
S-(L-glutamyl)-[peptidyl-carrier protein of nonribosomal peptide synthetase KtzH] + 2-oxoglutarate + O2
S-(threo-3-hydroxy-L-glutamyl)-[peptidyl-carrier-protein of nonribosomal peptide synthetase KtzH] + succinate + CO2
show the reaction diagram
A8CF77
the enzyme is involved in the biosynthesis of L-threo-3-hydroxy-glutamate, prior to incorporation into kutznerides (antifungal nonribosomal hexadepsipeptides)
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-
?