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1.14.13.244: phenol 2-monooxygenase (NADH)

This is an abbreviated version!
For detailed information about phenol 2-monooxygenase (NADH), go to the full flat file.

Reaction

phenol
+
NADH
+
H+
+
O2
=
catechol
+
NAD+
+
H2O

Synonyms

dmpLMNOP, DmpM, PheA

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.13.244 phenol 2-monooxygenase (NADH)

Inhibitors

Inhibitors on EC 1.14.13.244 - phenol 2-monooxygenase (NADH)

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
Co2+
1 mM, 80% residual activity
EDTA
0.1 mM, 77% inhibition
Fe3+
0.1 mM, 77% residual activity
Hg2+
0.1 mM, 87% inhibition
N-ethylmaleimide
0.1 mM, 62% residual activity
NaCl
0.1 mM, 48% inhibition
Ni2+
0.1 mM, 21% residual activity
o-phenanthroline
0.1 mM, 100% inhibition
p-chloromercuribenzoate
0.1 mM, 87% inhibition
p-hydroxymercuribenzoate
0.02 mM, no residual activity
Zn2+
1 mM, 23% residual activity
additional information
not inhibitory: phenol at 0.5 mM
-