1.14.19.79: 3beta,22alpha-dihydroxysteroid 3-dehydrogenase
This is an abbreviated version!
For detailed information about 3beta,22alpha-dihydroxysteroid 3-dehydrogenase, go to the full flat file.
Reaction
Synonyms
3beta,22-dihydroxysteroid 3-dehydrogenase, CPD, CPD/CYP90A1, CYP90A1, CYP90A1/CPD
ECTree
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Substrates Products
Substrates Products on EC 1.14.19.79 - 3beta,22alpha-dihydroxysteroid 3-dehydrogenase
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REACTION DIAGRAM
(22R,23R)-22,23-dihydroxycampesterol + [reduced NADPH-hemoprotein reductase] + O2
(22R,23R)-22,23-dihydroxycampest-4-en-3-one + [oxidized NADPH-hemoprotein reductase] + 2 H2O
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?
(22S)-22-hydroxycampesterol + [reduced NADPH-hemoprotein reductase] + O2
(22S)-22-hydroxycampest-4-en-3-one + [oxidized NADPH-hemoprotein reductase] + 2 H2O
preferred reaction
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?
6-deoxocathasterone + [reduced NADPH-hemoprotein reductase] + O2
(22S)-22-hydroxy-5alpha-campestan-3-one + [oxidized NADPH-hemoprotein reductase] + 2 H2O
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?
6-deoxocathasterone + [reduced NADPH-hemoprotein reductase] + O2
6-deoxoteasterone + [oxidized NADPH-hemoprotein reductase] + 2 H2O
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?
6-deoxoteasterone + [reduced NADPH-hemoprotein reductase] + O2
3-dehydro-6-deoxoteasterone + [oxidized NADPH-hemoprotein reductase] + 2 H2O
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?
additional information
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no activity with cathasterone, campestanol, campesterol, (22S)-22-hydroxycampest-4-en-3-one, (22S)-22-hydroxy-5alpha-campestan-3-one, 3-epi-6-deoxocathasterone, 3-dehydro-6-deoxoteasterone, 6-deoxotyphasterol, 6-deoxocastasterone, castasterone, and brassinolide
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