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1.14.19.79: 3beta,22alpha-dihydroxysteroid 3-dehydrogenase

This is an abbreviated version!
For detailed information about 3beta,22alpha-dihydroxysteroid 3-dehydrogenase, go to the full flat file.

Reaction

(22S)-22-hydroxycampesterol
+
[reduced NADPH-hemoprotein reductase]
+
O2
=
(22S)-22-hydroxycampest-4-en-3-one
+
[oxidized NADPH-hemoprotein reductase]
+ 2 H2O

Synonyms

3beta,22-dihydroxysteroid 3-dehydrogenase, CPD, CPD/CYP90A1, CYP90A1, CYP90A1/CPD

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.19 With oxidation of a pair of donors resulting in the reduction of O2 to two molecules of water
                1.14.19.79 3beta,22alpha-dihydroxysteroid 3-dehydrogenase

Substrates Products

Substrates Products on EC 1.14.19.79 - 3beta,22alpha-dihydroxysteroid 3-dehydrogenase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
(22R,23R)-22,23-dihydroxycampesterol + [reduced NADPH-hemoprotein reductase] + O2
(22R,23R)-22,23-dihydroxycampest-4-en-3-one + [oxidized NADPH-hemoprotein reductase] + 2 H2O
show the reaction diagram
-
-
-
?
(22S)-22-hydroxycampesterol + [reduced NADPH-hemoprotein reductase] + O2
(22S)-22-hydroxycampest-4-en-3-one + [oxidized NADPH-hemoprotein reductase] + 2 H2O
show the reaction diagram
preferred reaction
-
-
?
6-deoxocathasterone + [reduced NADPH-hemoprotein reductase] + O2
(22S)-22-hydroxy-5alpha-campestan-3-one + [oxidized NADPH-hemoprotein reductase] + 2 H2O
show the reaction diagram
-
-
-
?
6-deoxocathasterone + [reduced NADPH-hemoprotein reductase] + O2
6-deoxoteasterone + [oxidized NADPH-hemoprotein reductase] + 2 H2O
show the reaction diagram
-
-
-
?
6-deoxoteasterone + [reduced NADPH-hemoprotein reductase] + O2
3-dehydro-6-deoxoteasterone + [oxidized NADPH-hemoprotein reductase] + 2 H2O
show the reaction diagram
-
-
-
?
additional information
?
-
no activity with cathasterone, campestanol, campesterol, (22S)-22-hydroxycampest-4-en-3-one, (22S)-22-hydroxy-5alpha-campestan-3-one, 3-epi-6-deoxocathasterone, 3-dehydro-6-deoxoteasterone, 6-deoxotyphasterol, 6-deoxocastasterone, castasterone, and brassinolide
-
-
-