2.1.1.181: 23S rRNA (adenine1618-N6)-methyltransferase

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For detailed information about 23S rRNA (adenine1618-N6)-methyltransferase, go to the full flat file.

Reaction

Synonyms

EC 2.1.1.48, m6A1618 methyltransferase, rlmF, rRNA large subunit methyltransferase F, ybiN, YbiN protein

ECTree

     2 Transferases

         2.1 Transferring one-carbon groups

             2.1.1 Methyltransferases

                2.1.1.181 23S rRNA (adenine1618-N6)-methyltransferase

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Results	in table
5696	AA Sequence
1	Cloned(Commentary)
2	General Information
1	Molecular Weight [Da]
1	Natural Substrates/ Products (Substrates)
1	Organism
1	pH Optimum
1	Purification (Commentary)
1	Reaction
1	Reference
2	Substrates and Products (Substrate)
1	Subunits
6	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]

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General Information on EC 2.1.1.181 - 23S rRNA (adenine1618-N6)-methyltransferase

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GENERAL INFORMATION

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

malfunction

Escherichia coli

P75782

knockout of the ybiN gene leads to loss of modification at adenine1618. The modification is restored if ybiN knock-out strain has been co-transformed with a plasmid expressing the ybiN gene. Both lack of the ybiN gene and it's overexpression leads to growth retardation and loss of cell fitness comparative to the parental strain

705116

physiological function

Escherichia coli

P75782

A1618 modification could be necessary for the exit tunnel interaction with some unknown regulatory peptides

705116