2.4.2.62: xylosyl alpha-1,3-xylosyltransferase
This is an abbreviated version!
For detailed information about xylosyl alpha-1,3-xylosyltransferase, go to the full flat file.
Word Map on EC 2.4.2.62
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2.4.2.62
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notch
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glycosyltransferases
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o-glucosylation
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factor-like
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glycans
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glucoside
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o-glucosyltransferase
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trisaccharide
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renamed
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nsclc
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anomeric
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udp-glucose
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o-glucose
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o-linked
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sni-like
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musculus
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korean
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nominal
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non-small
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ethnic
- 2.4.2.62
- notch
- glycosyltransferases
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o-glucosylation
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factor-like
- glycans
- glucoside
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o-glucosyltransferase
- trisaccharide
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renamed
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nsclc
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anomeric
- udp-glucose
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o-glucose
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o-linked
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sni-like
- musculus
-
korean
-
nominal
-
non-small
-
ethnic
Reaction
Synonyms
C3ORF21, UDP-xylose:alpha-xyloside alpha1,3-xylosyltransferase, XXYLT1, xyloside alpha-1,3-xylosyltransferase, xyloside alpha1-3 xylosyltransferase, xyloside xylosyltransferase 1
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Substrates Products
Substrates Products on EC 2.4.2.62 - xylosyl alpha-1,3-xylosyltransferase
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REACTION DIAGRAM
UDP-alpha-D-xylose + Xyl-Glc-O-[protein with EGF-like domain 16]
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UDP-alpha-D-xylose + Xylalpha(1->3)Xylalpha(1->3)Glcbeta-O-(CH2)3NHCOC7H15
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UDP-alpha-D-xylose + [protein with EGF-like domain]-3-O-[alpha-D-xylosyl-(1->3)-beta-D-glucosyl]-L-serine
UDP + [protein with EGF-like domain]-3-O-[alpha-D-xylosyl-(1->3)-alpha-D-xylosyl-(1->3)-beta-D-glucosyl]-L-serine
UDP-D-xylose + N-pyridin-2-yl-3-O-alpha-D-xylopyranosyl-beta-D-glucopyranosylamine
UDP + alpha-D-xylopyranosyl-(1-3)-alpha-D-xylopyranosyl-(1-3)-N-pyridin-2-yl-beta-D-glucopyranosylamine
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the structure of the transfer product isolated is confirmed by Smith degradation, mass spectrometry, and a- and y9-xylosidase digestions
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UDP-alpha-D-xylose + [protein with EGF-like domain]-3-O-[alpha-D-xylosyl-(1->3)-beta-D-glucosyl]-L-serine
UDP + [protein with EGF-like domain]-3-O-[alpha-D-xylosyl-(1->3)-alpha-D-xylosyl-(1->3)-beta-D-glucosyl]-L-serine
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UDP-alpha-D-xylose + [protein with EGF-like domain]-3-O-[alpha-D-xylosyl-(1->3)-beta-D-glucosyl]-L-serine
UDP + [protein with EGF-like domain]-3-O-[alpha-D-xylosyl-(1->3)-alpha-D-xylosyl-(1->3)-beta-D-glucosyl]-L-serine
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UDP-alpha-D-xylose + [protein with EGF-like domain]-3-O-[alpha-D-xylosyl-(1->3)-beta-D-glucosyl]-L-serine
UDP + [protein with EGF-like domain]-3-O-[alpha-D-xylosyl-(1->3)-alpha-D-xylosyl-(1->3)-beta-D-glucosyl]-L-serine
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the enzyme participates in the biosynthesis of the Glc-O-Ser-type sugar chains
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additional information
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the enzyme cannot act on a synthetic acceptor containing an alpha-linked xylose alone and has no activity with 4-nitrophenyl-alpha-D-xylose and Xyl-O-[protein with EGF-like domain]
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additional information
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the enzyme cannot act on a synthetic acceptor containing an alpha-linked xylose alone and has no activity with 4-nitrophenyl-alpha-D-xylose and Xyl-O-[protein with EGF-like domain]
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